Important Notice

Important Notice

This is the old and inactive website of Acta Medica Iranica & is NO longer used for issues publishing and manuscripts submission. To gain access to the new published issues and also submitting new manuscripts, go to journal new website at: 



COPE Member

This journal is a member of, and subscribes to the principles of, the
Committee on Publication Ethics (COPE).



to my email:
Acta Medica Iranica
2009;47(1) : 51-56
Original Report
The Effect of Ginger Biscuit on Nausea and Vomiting in Early Pregnancy

Zahra Basirat*1, Ali A. Moghadamnia2, Mehrdad Kashifard3, Atena Sarifi-Razavi1
1 Department of Obstetric and Gynecology, School of Medicine, Babol University of Medical Sciences, Babol, Iran
2 Department of Pharmacology, School of Medicine, Babol University of Medical Sciences, Babol, Iran
3 Department of Gastroentrology, School of Medicine, Babol University of Medical Sciences, Babol, Iran

Corresponding Author:
Zahra Basirat

Department of Gynecology, Fatemeh Zahra Fertility and Infertility Research Center, Babol University of Medical Sciences, Babol Postal. Code: 4719173716 Iran.

Tel: +98 911111-2979, Fax: +98 111 2274880, E-mail:

Received:October 15,2006
Accepted: September 21,2007

Nausea and vomiting of pregnancy (NVP) are often alleviated by eating dried biscuits or foods. Natural products such as ginger have been suggested as herbal remedies for its treatment. The purpose of this study was to determine the effectiveness of ginger in biscuit form for the treatment. Sixty-five women with NVP at or before 17 weeks of gestation, who attended the antenatal clinic of Yahyanejad hospital in Babol town, Northern Iran, during 2005-2006 were included in the study. The subjects were randomized in a double-blind design and divided into two groups to take biscuits. 0.5g of ginger as fine powder was incorporated in each biscuit. Subjects received 5 ginger biscuits per day or an identical placebo biscuit for 4 days. They graded their severity of nausea using visual analog scales (VAS) and recorded the number of vomiting episodes in the previous 24 hours and again during 4 consecutive days. Five-item Likert scales were used to assess the severity of their symptoms. The average VAS scores of day 1 to 4 of post-therapy minus baseline nausea was decreased significantly in ginger (2.6±1.77) compared with the placebo group (1.4±1.62) (P=0.01). The number of vomiting episodes was also decreased in ginger (0.96±0.21) and placebo (0.62±0.19), the difference being insignificant. A significant difference was seen in inter-group variations per day in both groups. Likert scale showed an improvement in symptoms in both groups (P=0.43). Therefore, ginger in biscuit form is effective for relieving the severity of nausea and, to some extent, of vomiting in pregnancy.

Nausea ،  vomiting ،  pregnancy ،  ginger ،  biscuit
Permanent Link:
    179 KB
Home | About Us 2004-2012
Best view with Internet Explorer 6 or Later at 1024*768 Resolutions