Send
to my email:
Journal of Diabetes and Metabolic Disorders (Formerly: Iranian Journal of Diabetes and Lipid Disorders)
2008;7:3
 
Effect of processed Berberis vulgaris in apple vinegar on blood pressure and inflammatory markers in type 2 diabetic patients

Golzarand M*1, Ebrahimi-Mamaghani M2, Arefhosseini SR3, Ali Asgarzadeh A4

1- Faculty of Health and Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.

2- Nutritional Research Center , Tabriz University of Medical Sciences, Tabriz, Iran.

3- Department of Nutrition and Biochemistry, Faculty of Health and Nutrition, Tabriz University of Medical Sciences, Tabriz,  Iran.

4- Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

 

Corresponding Author:
 

Golzarand, Mahdieh
Number 14 , Mozafari alley,  Shahid kazemi St. , Sina Av. ,  Navab High way, Tehran- Iran, Tel: + 98 9122305384, E-mail: mahdieh_golzarand@yahoo.com

Received:February 16,2008
Accepted: May 31,2008
Available online:November 1,2008
Abstract:

Background: Hypertension and increased inflammatory markers in type 2 diabetic patients are two major risk factors of cardiovascular diseases. Therefore, management of these two cardiovascular diseases risk factors is of the first magnitude in type 2 diabetic patients. This study was aimed to determine effect of processed Berberis vulgaris on blood pressure and inflammatory markers in type 2 diabetic patients.

Methods: Type 2 diabetic patients were recruited into a clinical trial (n =57) and randomly assigned into 3 groups: 1) processed B. vulgaris (n =19), daily consumption of 1 Tsp processed B.vulgaris in apple vinegar, 2) apple vinegar group (n =19), daily consumption of 2 Tsp apple vinegar and 3) control group with no intervention. Nutritional intake, anthropometric indices, inflammatory markers and systolic- and diastolic blood pressure were measured at the baseline and the end of 8th  week.

Results: At the end of 8 weeks, mean of nutritional intake, anthropometric indices, hs CRP concentration, systolic- and diastolic blood pressure did not change in processed B.vulgaris, apple vinegar and control groups significantly.  Interleukin-6 concentration did not shift in processed B.vulgaris and control groups but in apple vinegar group decreased significantly.

Conclusion: These findings had shown processed B.vulgaris had no effect on systolic- and diastolic blood pressure but apple vinegar had positive effect on interleukin-6. Nevertheless, further investigations about B.vulgaris effect on blood pressure and inflammatory markers are necessary.

Keywords:
Berberis ،  Systolic Pressure ،  Diastolic Pressure ،  Interleukine 6
Permanent Link: http://journals.tums.ac.ir/abs/12025
    142 KB
 
 
 
 
Home | About Us

IRJournals.com 2004-2012
 
Best view with Internet Explorer 6 or Later at 1024*768 Resolutions