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Survey of saccadic parameters using videonystagmography in patients with idiopathic Parkinson's disease and normal subjects
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Reza Hosseinabadi1   , Abdorreza Sheibanizadeh * 2, Gholamali Shahidi3 , Arash Gholamipur3 , Mohammad Kamali4 |
1- MSc. in Audiology, Faculty of Rehabilitation Sciences, Iran University of Medical Sciences, Iran.
2- Audiology Department, Faculty of Rehabilitation Sciences, Iran University of Medical Sciences, Ira
3- Neurology Department, School of Medicine, Iran University of Medical Sciences, Iran
4- Management of Rehabilitation Department, Faculty of Rehabilitation Sciences, Iran University of Med |
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Abstract: (8165 Views) |
Background and Aim: Patients with Parkinson&aposs disease manifest oculomotor abnormalities. This is the consequence of basal ganglia impairment. The most common abnormalities include increased saccade latency, hypometric saccades and decreased saccade velocity. The purpose of this study was comparison of saccadic parameters using videonystagmography in patients with idiopathic Parkinson&aposs disease and normal subjects.
Materials and Methods: In this cross sectional study, saccadic movements were investigated in thirty patients with idiopathic Parkinson&aposs disease and thirty age matched subjects were 35-70 years old. Saccade latency, velocity and accuracy were quantitatively analyzed.
Results: Results of this study indicated increased saccade latency, reduction of saccade velocity and accuracy in patients with Parkinson&aposs disease(P<0.001).
Conclusion: This study showed that patients with Parkinson&aposs disease manifest saccadic deficits. This suggests dopaminergic control of these ocular movements. |
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| Keywords: Oculomotor, Saccade, Basal ganglia disorders |
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Full-Text [PDF 168 kb]
(3511 Downloads)
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Type of Study: Research |
Received: 2008/04/12 | Accepted: 2008/07/8 | Published: 2013/10/9
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