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Showing 1 results for Saccade
Reza Hosseinabadi, Abdorreza Sheibanizadeh, Gholamali Shahidi, Arash Gholamipur, Mohammad Kamali, Volume 17, Issue 1 (11-2008)
Abstract
Background and Aim: Patients with Parkinson&aposs disease manifest oculomotor abnormalities. This is the consequence of basal ganglia impairment. The most common abnormalities include increased saccade latency, hypometric saccades and decreased saccade velocity. The purpose of this study was comparison of saccadic parameters using videonystagmography in patients with idiopathic Parkinson&aposs disease and normal subjects. Materials and Methods: In this cross sectional study, saccadic movements were investigated in thirty patients with idiopathic Parkinson&aposs disease and thirty age matched subjects were 35-70 years old. Saccade latency, velocity and accuracy were quantitatively analyzed. Results: Results of this study indicated increased saccade latency, reduction of saccade velocity and accuracy in patients with Parkinson&aposs disease(P<0.001). Conclusion: This study showed that patients with Parkinson&aposs disease manifest saccadic deficits. This suggests dopaminergic control of these ocular movements.
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