Masking is a necessary part in ABR test the same as other Audiological experiments to obtain the real responses without the intrusion of the other ear. In the current research we are aimed at studying the effect of the masking noise on the pure latency of wave V and interwave latencies of I-III, III-V and I-V. Noise was delivered to the non test ear with intensities of 0, 30, 50 and 70 dB in four different sessions while the intensity level of the stimulus was fixed in all four sessions.

Objectives: Introducing an approach for diagnosing the normal ABR independently or supplementary used to confirm the results of the other approaches.
Materials and Methods: This study was carried out in a descriptive manner on 31 male students of audiology in the Rehabilitation Faculty which were not chosen randomly. All of the samples aged between 18 to 25 years old with normal hearing and with no history of hearing disorder. They were tested in the winter of 1377 by ABR. The resulted of their ABR tests (62 curves) were in accordance with the convenient latency norms. After the preparation stage, the frequency analysis of the curves was considered through the Fast Fourier Transform function.
Results: considering the power and phase spectrum, three components are recognized, and phase for their frequency, amplitude and phase are determined.The normative values of the obtained amounts of the frequency, amplitude and phase for the frequency analysis results of the normal ABR curves are as follows:* First Component: Frequency: 340-530 Hz, Amplitude: 23-31 dB, Phase: 0-3 radian * Second Component: Frequency: 540-370 Hz, Amplitude: 20-30 dB, Phase: 0.3-2.7 radian * Third Component: Frequency: 750-1024 Hz, Amplitude: 19-30dB, Phase: 0-3.3 radian
onclusion: The results of the present study are exclusively valid for the society being considered, and their generalization requires more researches.

Methods and Materials: Investigation of electrically evoked auditory brain stem response (EABR) is a new issue, especially in implanted patients. Experiments were performed in C.I Center of Iranian Institute for Science and research expansion,1996 on 30 implanted patients with 22 spectra and MSP cochlear implant system and 30 normal subjects with the range of 3-33 years.Findings:1- EABR was obtained in the implanted patients.2- Absolute latency of EABR waves is 1-1.5 ms shorter than ABR waves ‘P<0.05).3-Absolute latency of wave V decreases as a function of electric stimulus magnitude (P<0.05).4- No significant difference was observed in IPL Ill-V between ABR and EABR.

Objective: Comparison of Air conduction (AC) and Bone conduction (BC) auditory brain stem response (ABR) latencies.
Materials and Methods: In this cross-sectional study, 34 (17 males, 17 females) normal-hearing young subjects tested with AC- and BC-ABR .Wave V latencies of both procedures were compared
Results: BC- wave V latency significantly prolonged about 0.5 ms. That prolongation was less with decreasing intensity. Females&apos AC-and BC - ABR latencies were less than males&apos.
Conclusion: AC- and BC- ABR appeared to be useful to determine sensory-neural acuity in children with atresia or difficult to test subjects specially newborns.

Background and Aim: Learning disability(LD) is one of the most prevalent problems among elementary school children. Approximately 10 percent of all elementary school children suffer from this problem. It has been determined that learning disability is predominantly accompanied with subtle impairment in central auditory nervous system. The main idea of this study was to evaluate middle latency auditory evoked potential (MLAEPs) in learning disabled children.

Materials and Method: This cross-sectional study investigated middle latency auditory evoked potential in children with learning disability (n = 31) compared to normal children (n = 31). Latencies and amplitudes of MLAEPs results with different stimulus intensity and binaural stimulation were compared between two groups.

Results: Compared to control group, learning disabled children exhibited smaller amplitudes for all the components except the right ear Na and Pa. There is no significant difference between two groups for latencies of the components.

Conclusion: It seems that middle latency auditory evoked potential may be useful in diagnosis and evaluation of learning disabled children although more investigation is required.

Background and Aim: Middle latency auditory evoked potentials (MLAEPs) development takes longer time than the auditory brainstem response (ABR) development does, which makes them difficult to record in some children. The purpose of this study was to investigate the age effect on characteristics and detection of MLAEPs in children and adults.
Materials and Methods: This cross sectional study was conducted on 15 children aged   7-12 yr and 31 adults aged 20-50 yr with normal peripheral hearing. To investigate precisely, children were divided in two subgroups of older and younger than 10 years old, as well. The MLAEPs amplitudes and latencies were recorded by conventional protocol and compared.
Results: Adult Na mean latency, 20.86 ms, was less than that of children, 22.86 ms, (p=0.0025).  In contrast, the adult Nb mean latency, 44.93 ms, was longer (p=0.0001). Children Nb mean latency was 42.02 ms. There was no significant difference in MLAEP amplitudes and latencies between two children subgroups, although variance was more in younger children.
Conclusion: MLAEPs are reliably recorded after 7 years old. Characteristics of MLAEPs are different in adults and children so that the primary MLAEPs generators have a course of development extending beyond the first decade of life. As those potentials were recorded in all children, it is suggested to be used in their test batteries for hearing evaluation.

Background and Aim: Blocking of the adenosine receptor in central nervous system by caffeine can lead to increasing the level of neurotransmitters like glutamate. As the adenosine receptors are present in almost all brain areas like central auditory pathway, it seems caffeine can change conduction in this way. The purpose of this study was to evaluate the effects of caffeine on latency and amplitude of auditory brainstem response(ABR).
Materials and Methods: In this clinical trial study 43 normal 18-25 years old male students were participated. The subjects consumed 0, 2 and 3 mg/kg BW caffeine in three different sessions. Auditory brainstem responses were recorded before and 30 minute after caffeine consumption. The results were analyzed by Friedman and Wilcoxone test to assess the effects of caffeine on auditory brainstem response.
Results: Compared to control group the latencies of waves III,V and I-V interpeak interval of the cases decreased significantly after 2 and 3mg/kg BW caffeine consumption. Wave I latency significantly decreased after 3mg/kg BW caffeine consumption(p<0.01).
Conclusion: Increasing of the glutamate level resulted from the adenosine receptor blocking brings about changes in conduction in the central auditory pathway.

Background and Aim: Tinnitus is an unpleasant sound which can cause some behavioral disorders. According to evidence the origin of tinnitus is not only in peripheral but also in central auditory system. So evaluation of central auditory system function is necessary. In this study Auditory brainstem responses (ABR) were compared in noise induced tinnitus and non-tinnitus control subjects.
Materials and Methods: This cross-sectional, descriptive and analytic study is conducted in 60 cases in two groups including of 30 noise induced tinnitus and 30 non-tinnitus control subjects. ABRs were recorded ipsilateraly and contralateraly and their latencies and amplitudes were analyzed.
Results: Mean interpeak latencies of III-V (p= 0.022), I-V (p=0.033) in ipsilatral electrode array and mean absolute latencies of IV (p=0.015) and V (p=0.048) in contralatral electrode array were significantly increased in noise induced tinnitus group relative to control group.
Conclusion: It can be concluded from that there are some decrease in neural transmission time in brainstem and there are some sign of involvement of medial nuclei in olivery complex in addition to lateral lemniscus.

Background and Aim: Vestibular evoked myogenic potentials and acoustically evoked short latency negative response are two non-cochlear responses with probably saccular origin. The present study was conducted to determine the percentage of presence and the relation between these two responses in children with hearing loss.
Methods: Thirty children with profound congenital sensorineural hearing loss were studied.  Vestibular evoked myogenic potentials ellicitedby tone burst stimuli and acoustically evoked short latency negative response ellicited by click stimuli were recorded. Both responses were recorded at air conduction threshold level monaurally via an internal receiver.
Results: Vestibular evoked myogenic potentials in 53.3% of children and acoustically evoked short latency negative response in 40.0% of cases were recorded. There was a significant correlation between the percentage of recording these two responses (p=0.005). Gender and the stimulated ear had no effect on the results.
Conclusion: In almost half of these disabled children, both vestibular evoked myogenic potentials and acoustically evoked short latency negative response were recoreded. This finding may both indicate that hearing loss has no effect on the function of otolith organs in some children and vestibular deficits probably exist along with hearing impairment in others. This findng reiterates the importance of evaluation of vestibular system as part of standard auditory evaluations.

Background and Aim: A negative deflection with a 3-4 ms latency period has been reported to exist within the auditory brainstem response of some patients with profound hearing loss following a strong acoustic stimulus. This deflection, namingly the n3 or the acoustically evoked short latency negative response is assumed to be a vestibular-evoked potential, especially of saccular origin. Since the myogenic potential is also saccular in origin, the purpose of the present study was to investigate the relationship between these two tests in adults with profound hearing loss.
Methods: The present cross sectional study was performed on 20 profoundly deaf volunteers(39 ears) who aged between 18-40 years old, randomly selected from available deaf adults in Tehran. The auditory brainstem response of all subjects was recorded following a 1000 Hz tone burst in 70-100dB nHL. Subjects were also tested for vestibular evoked myogenic potential.
Results: Only 34 of 39 ears recorded myogenic potential that negative response was recorded in 27 of 34 ears with normal p13 and n23. In seven ears with normal p13 and n23, the negative response was absent. In 3 ears with no p13 and n23, the negative response was observed, and two none.
Conclusion: In view of the high prevalance of the negative response in profoundly deaf ears with normal p13 and n23, it could be concluded that the negative response can be used when for any reason, it is not possible to record myogenic potential and be considered as a new test in vestibular test battery.

Background and Aim: Preterm birth is one of the risk factors need comprehensive audiological assessment. In this study, the effect of sex and rate of stimulation on response of children with history of preterm birth was investigated by auditory brainstem response (ABR).

Methods: This cross-sectional study was conducted using convinience sampling. Click-evoked a uditory brainstem response test with both low (21.1 c/s) and high (51.1 c/s) stimulus rates was recorded in 30 children with a history of preterm birth and 30 ones with history of term labor, as controls.

Results: Significant differences were observed in inter-peak latencies of I-III in both rates, III-V in the low rate, I-V in the high rate, and absolute latency of III wave between high and low stimulus rates (p<0.05 for all). Rate of stimulus affect on auditory brainstem response of preterm birth group was more than controls. Sex also affected on some parameters of auditory brainstem response test.

Conclusion: Preterm birth group showed longer latencies than normal group in both rates. Rate of stimulus had significant effect on results of children with history of preterm birth compared normal group. These findings may reflect the negative effect of preterm birth on neural synchronization function in response to transient stimuli.