Background and Aim: The purpose of the present study was to investigate the effect of vestibulo-proprioceptive stimulations of sensory integration theory on the development of gross and fine motor, language and personal-social functions in a child with agenesis of the corpus callosum.

Case: We report a 10.5 month old boy with agenesis of the corpus callosum. The intervention was administered based on sensory integration theory an hour a week for 20 weeks. The exercise intervention consisted of proprioceptive and linear, sustained and low frequency vestibular stimulations on suspension device and physio roll. A Denver Developmental Screening- II and milestones skill testing was completed pre-intervention and monthly. Post-intervention, age of gross motor, fine motor adaptive, language, and personal-social functions significantly improved. Based on milestones skills, maintenance of gross motor functions (e.g. sitting and quadruped position) improved. The child could roll from side to side and released objects voluntarily. The reaction time to auditory stimulations became less than 2 seconds.

Conclusion: vestibulo-proprioceptive stimulations using the neuroplasticity ability of the central nervous system is effective for development of gross and fine motor, language, and personal-social functions. These exercises can be administered for a child with agenesis of the corpus callosum.

Background and Aim: Previous studies suggest that auditory stimulus frequency in normal subjects contribute to both P300 amplitude and latency measures. As occipital cortex devotes to other modalities including auditory inputs, the purpose of this study was to determine the effects of stimulus frequency in early blind subjects.
Methods: fifteen early blind subjects (8 males and 7 females) with mean age of 25.13±4.27 years were tested. Cognitive potential P300 was recorded in response to high (1000/2000 Hz ) and low (250/500 Hz) frequencies auditory stimuli using an oddball task in 70 dB nHL. While participants answered to target stimulus, amplitude and latency of P300 was recorded.
Results: With high frequency stimuli, mean amplitude in early onset blind subjects obtained 14.13 ±5.53µv and was 17.59±8.17µv with low frequency. With high and low frequency, mean latency of P300 obtained 295.60±31.33ms and 317.38±21.71ms respectively.
Comparison of results between two stimuli showed that there were statistically significant differences between amplitudes (p=0.008) and latencies (p=0.001) of cognitive potential P300.
Conclusion: Changing low frequency to high frequency results in decreasing both amplitude and latency. It seems that auditory stimuli frequency affect the P300 parameters in blind subjects.

Background and Aims: Main feature of auditory processing abilities is temporal processing including temporal resolution, temporal ordering, temporal integration and temporal masking. Many studies have shown the superiority of blinds in temporal discrimination over sighted subjects. In this study, temporal processing was compared in congenital blind subjects with sighted controls via gap in noise test (GIN).
Methods: This analytic-prescriptive non-invasive cohort study was conducted on 22 congenital blinds (11 males and 11 females) with a mean age of 26.22 years and 22 sighted control subjects (11 males and 11 females) with a mean age of 24.04 years with normal hearing in faculty of Rehabilitation Tehran University of Medical Sciences. Gap in noise test results, approximate threshold and percent of corrected answers, were obtained and then, were analyzed by Mann-Whitney non-parametric statistical test.
Results: There was a significant difference in the approximate threshold and the percent of corrected answers between congenital blinds and sighted control subjects (p<0.05). However, there was no significant difference between males and females in this regard (p>0.05).
Conclusion: Auditory temporal resolution ability, the lower approximate threshold and the more corrected answers in gap in noise, in blind subjects is better than the sighted control group and it might be related to the compensative neuroplasticity after visual deprivation.