Journal of Hayat
حیات
Hayat
Medical Sciences
http://hayat.tums.ac.ir
1
admin
1735-2215
2008-188X
fa
jalali
1404
10
1
gregorian
2026
1
1
31
4
online
1
fulltext
fa
بررسی تأثیر بهکارگیری محلول دیالیز سرد بر کیفیت خواب و تغییرات فشارخون حین همودیالیز در بیماران مبتلا به مرحله آخر نارسایی کلیه: یک مطالعه کارآزمایی بالینی
Studying the effect of using cold dialysis solution on sleep quality and blood pressure changes during hemodialysis in patients with end-stage renal failure: A clinical trial study
مراقبتهاي پرستاري
Nursing Care
پژوهشي
Research
<span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">زمینه و هدف: </span></span></span></span></i></b><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">نارسایی کلیه مرحله آخر، نیازمند برنامهریزی دقیق و مؤثر در فرآیند همودیالیز است تا کیفیت زندگی بیماران بهبود یابد و عوارض مرتبط کاهش یابد. </span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">لذا، مطالعه حاضر با هدف تعیین تأثیر بهکارگیری محلول دیالیز سرد بر کیفیت خواب و تغییرات میانگین فشارخون حین همودیالیز در بیماران مبتلا به مرحله آخر نارسایی کلیه انجام گرفته است</span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">.</span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span style="color:black"><span style="letter-spacing:-.2pt"></span></span></span></i></span></span></span></span></span><br>
<span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">روش بررسی:</span></span></span></span></i></b><i> </i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">در این مطالعه کارآزمایی بالینی تصادفی کورسازی شده، 82 فرد مبتلا به مرحله آخر نارسایی کلیه تحت همودیالیز در بیمارستانهای بقیهالله و میلاد تهران در سال 1402 بهصورت تصادفی در گروه مداخله (41 نفر) و کنترل (41 نفر) اختصاص یافته و ارزیابی شدند. گروه مداخله با </span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">محلول همودیالیز سرد (</span></span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">۳۵</span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt"> درجه سانتیگراد) </span></span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">و گروه کنترل </span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">با محلول همودیالیز استاندارد (</span></span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">۳۷</span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt"> درجه سانتیگراد)</span></span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt"> به مدت 4 هفته همودیالیز شدند. ابزار جمعآوری دادهها </span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">فرم مشخصات جمعیتشناختی و بیماری، </span></span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">پرسشنامه کیفیت خواب ریچاردکمپل (</span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"><span style="letter-spacing:-.2pt">RCSQ</span></span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">) و دستگاه فشارخون سنج جیوهای بود. </span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">تجزیه و تحلیل </span></span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">د</span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">ادهها در نرمافزار </span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"><span style="letter-spacing:-.2pt">SPSS</span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt"> نسخه 26 با استفاده از آزمونهای آماری </span></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"><span style="letter-spacing:-.2pt">Mann-Whitney</span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">، </span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">تیمستقل، کایاسکوئر </span></span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">و </span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">تیزوجی انجام گرفت</span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:-.2pt">.</span></span></span></span></i></span></span></span></span></span><br>
<span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="tab-stops:163.05pt"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:.1pt">یافتهها</span></span></span></span></i></b><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:.1pt">: </span></span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">میانگین نمره کیفیت خواب در گروه همودیالیز سرد (</span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">۳۵</span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"> درجه) پس از دیالیز بهطور معناداری بالاتر از گروه استاندارد (</span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">۳۷</span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"> درجه) بود</span></span></span></i><i> </i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">(004</span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">/0=</span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">p</span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">).</span></span></span></i><i> </i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">قبل از دیالیز تفاوت معناداری بین دو گروه مشاهده نشد</span></span></span></i><i> </i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">( 759</span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">/0=</span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">p</span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">).</span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"> میانگین نمره <strong><span b="" style="font-family:" yagut="">فشارخون سیستولیک و دیاستولیک</span></strong></span></span></span></i><i> </i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">قبل از دیالیز تفاوت معناداری بین دو گروه وجود نداشت. اما پس از دیالیز، کاهش فشارخون (سیستولیک و دیاستولیک) در گروه همودیالیز سرد بهطور معناداری کمتر از گروه استاندارد بود (</span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">001/0></span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">p</span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">)</span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black"><span style="letter-spacing:.1pt">.</span></span></span></span></i></span></span></span></span></span></span><br>
<span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">نتیجهگیری: </span></span></span></i></b><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">نتایج این کارآزمایی بالینی نشان داد که استفاده از محلول دیالیز سرد در حین همودیالیز، به طور معنادار کیفیت خواب بیماران مبتلا به مرحله آخر نارسایی کلیه را بهبود بخشیده و تغییرات فشارخون حین درمان را کاهش داده است. </span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">این یافتهها</span></span></span></i><i> </i><i><span lang="AR-SA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">میتواند در راستای بهبود فرآیند درمان و ارتقای کیفیت زندگی این بیماران به کار گرفته شود</span></span></span></i><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">.</span></span></span></i><i><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black"></span></span></span></i></span></span></span></span></span><br>
<span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><i><span lang="FA" style="font-size:10.0pt"><span b="" style="font-family:" yagut=""><span style="color:black">ثبت کارآزمایی بالینی:</span></span></span></i></b><i> </i><i><span dir="LTR" style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="color:black">IRCT20230521058244N1</span></span></span></i><i><span lang="AR-SA" style="font-size:10.0pt"><span style="font-family:"B Yagut""></span></span></i></span></span></span></span></span><br>
<span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="direction:rtl"><span style="unicode-bidi:embed"><i><span dir="LTR" style="font-size:10.0pt"></span></i></span></span></span></span></span><br>
<span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="vertical-align:top"><b><span style="font-size:10pt"><span new="" roman="" style="font-family:" times=""><span style="letter-spacing:-0.1pt">Background & Aim:</span></span></span></b> <span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">End-stage renal failure requires careful and effective planning in the hemodialysis process to improve patients' quality of life and reduce complications. Therefore, this study aimed to investigate the impact of using cold dialysis solution on sleep quality and blood pressure changes during hemodialysis in patients with end-stage renal failure<span style="letter-spacing:-0.1pt">.</span></span></span></span></span></span></span><br>
<span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="vertical-align:top"><b><span style="font-size:10pt"><span new="" roman="" style="font-family:" times=""><span style="letter-spacing:-0.1pt">Methods & Materials:</span></span></span></b> <span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times=""><span style="letter-spacing:-.1pt">This blinded randomized clinical trial included 82 patients undergoing hemodialysis in Baqiyatallah and Milad hospitals in Tehran in 2023. Patients were randomly assigned to either the intervention group (41 individuals) or the control group (41 individuals). The intervention group received hemodialysis with cold dialysis solution (35°C), while the control group received standard dialysis solution (37°C) for 4 weeks. Data was collected using a demographic and disease characteristics form, Richard Campbell Sleep Quality Questionnaire (RCSQ), and a mercury sphygmomanometer. Data analysis was conducted using SPSS version 26 software, utilizing Mann-Whitney, independent <i>t</i>-test, chi-square, and paired <i>t</i>-test.</span></span></span></span></span></span></span><br>
<span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><span style="vertical-align:top"><b><span style="font-size:10pt"><span new="" roman="" style="font-family:" times=""><span style="letter-spacing:-0.1pt">Results:</span></span></span></b> <span style="font-size:10pt"><span new="" roman="" style="font-family:" times="">The mean sleep quality score in the cold hemodialysis group (35°) after dialysis was significantly higher than the standard group (37°) (<i>P</i>=0.004). No significant difference was observed between the two groups before dialysis (<i>P</i>=0.759). There was no significant difference between the mean systolic and diastolic blood pressure scores before dialysis in the two groups. However, after dialysis, the reduction in blood pressure (systolic and diastolic) in the cold hemodialysis group was significantly less than in the standard group (<i>P</i><0.001)</span></span><span style="font-size:10pt"><span new="" roman="" style="font-family:" times=""><span style="letter-spacing:-0.1pt">.</span></span></span></span></span></span></span><br>
<span style="text-justify:kashida"><span style="text-kashida:0%"><span style="line-height:normal"><b><span style="font-size:10pt"><span new="" roman="" style="font-family:" times=""><span style="letter-spacing:-0.3pt">Conclusion:</span></span></span></b> <span style="font-size:10pt"><span new="" roman="" style="font-family:" times="">The results of this clinical trial showed that the use of cold dialysis solution during hemodialysis significantly improved the sleep quality of patients with end-stage renal failure and reduced blood pressure changes during treatment. These findings can be used to improve the treatment process and enhance the quality of life of these patients</span></span><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">.</span></span></span></span></span><br>
<b><span style="font-size:10.0pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">Clinical trial registry: </span></span></span></b><span style="font-size:10pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times="">IRCT20230521058244N1</span></span></span>
نارسایی کلیه, همودیالیز سرد, کیفیت خواب, فشارخون
renal failure, cold hemodialysis, sleep quality, blood pressure
409
422
http://hayat.tums.ac.ir/browse.php?a_code=A-10-2322-5&slc_lang=fa&sid=1
Ali
Hosseinzadeh
علی
حسینزاده