Journal of Dental Medicine

Growth factors and new periodontology

Growth factors are biological mediators that have a key roll in proliferation, chemotaxy and differentiation by acting on specific receptors on the surface of cells and regulating events in wound healing.They can be considered hormones that are not released in to the blood stream but have one a local action. Some of these factors can regulate premature change in GO to Gl phase in cell devesion cycle and even may stimulate synthesis of DNA in suitable cells, Growth substances, primarily secreted by fibroblasts, endothelia! cells, macrophages and platelet, include platelet derived growth factor (PDGF), insulin like growth factor (IGF) transforming growth factor (TGF)a and (3 and bone morphogenetic proteins BMPs that approximately are the most important of them. (BMP)s could be used to control events during periodontal, craniofacial and implant wound healing through favoring bone formation According toLynch, combination of PGDF and IGF1 would be effective in promoting growth of all the components of the periodontium.The aim of this study was to characterize growth factor and review the literature to determine the mechanism of their function, classification and application in implant and periodontal treatment.

Evaluating and comparison between wear behavior of dental Amalgam

MH. Fathi

Wear characteristics of dental amalgams were investigated by in vivo and in vitro tests. Wear of dental amalgam was studied and evaluated using a three - body abrasion test and Pin-On-Disk method. Porcelain was used for preparing disk and materials such as toothpaste, artificial saliva and naturally saliva were used as the third material that was contributed in tribologic system The results showed that effects of various toothpastes on the wear of dental amalgam are considerably different and size, shape and chemical composition of amalgam are important too.

Evaluation of Knowledge, Attitude and practice of private practioner in urmieh in 1376 (KAP.Study regard to O.H.I).

Y. Soleymani-e-Shayestheh

:.In the result of first world investigations, it has recommended that most oral and dental disease (over 80%) can be prevented by oral hygiene Instruction and sanitary methods.In our investigation, we have wanted to estimate the rate of knowledge, attitude and practice of dentists in urmieh. Our results exhibited that the rate of dentist's knowledge about sanitary and preventive methods and their etiologic relations of oral disease is 95%.But in spite of this high rate of knowledge the dentists attitude rate is %55.48 and more strange is that the practice of these dentist in relation with sanitary and preventive methods for patients has evaluated about 66.17% that ,this rate is 13% more than their attitude rate. The cause of this strange result, may be is dentists un honestly answer or because of their high theoretical knowledge of our dentist. May be we thinking that this recent factor in spite of insufficient attitude has effected on their practice.

Evaluation of different finish line designs in base metal alloys

This investigation was performed according to the widespread application of base metal alloys and few articles published about the marginal integrity of restorations fabricated by these metals.Three standard dies of a maxillary first premolar were prepared with a flat shoulder finish line in buccal aspect and chamfer in palatal. One of them left with no change. On the buccal aspect of the second and third dies 135?and 1607 bevel were added respectively Using dual wax technique, nine wax patterns were formed on each die and casting procedure of selected non precious alloy was performed by centrifugal method. Marginal gaps of each copping seated on dies were measured by scanning electron microscope (SEM) with X500 magnification. Measurements were done on three areas of marked dies on buccal aspect. Measurement son palatal aspect was done on marked midpalatal point as control.Results and statistical analysis showed no significant difference among marginal gaps in lingual aspect.But on the buccal aspect there were statistically significant differences among the groups (P<0.001). Flat shoulder had the best marginal integrity (mean 4 micron). Shoulder with 160' bevel had the most marginal gap (mean 26.5 micron) and shoulder with 1357 bevel was between two other groups (mean 15.7 micron).

Tow years evaluation of Effectiveness of caries preventive precisures

The purpose of this survey was the determine of effectiveness of preventive precisures. 320 twelve years school student have chosen randomly. After determination of DMFT All of them divided to 4 groups. First group as control and the other groups were as oral hygiene education 6-fluoride therapy and sealant therapy group in a period of two years.Results of this study showed that fluoride therapy was more effective than the other procisures than oral hygiene instructions.

Prevalence of ectopic eruption in first permanent molar in 8 years old Tehran school children

H. Afshar

In this study, by cluster simple random sampling, the prevalence of ectopic of first permanent molar in 8 years old Tehran school children is considered and determined as 0.87 percent The involvement of maxilla was more than mandible and the difference was significant. Bilateral involvement was more than unilateral and boys were more- than girls, how ever the differences were not significant. As for as the geographical distribution is considered, the differences were not noticeable, either.

Odontoma and Analysis of 57 different types

Odontoma is an odontogenic lesion with epithelial and mesenchymal origin and is composed of differentiated dental parts. Than because of abnormal organization of mature tissues. It seems that it is a hamartoma rather than real tumor. Odontoma is seen in two types of compound & complex.Out of 57 studied cases, 31 cases (54.2%) were of complex type 12 cases (21 %) were compound & 8 cases were of cystic. The age of incidence ranged from 5.5 to 68 years. The mean age in complex odontoma was 27 years & compound type was 19 years. There was no significant difference regarding the sex in the complex type. In compound odontoma women were affected 2 times more than means.Complex type are found in mandibular posterior era ereas more and compound type in anterior regions .In this studied found 12 cases impaction teeth.

The assessment of Ag NOR in grading of head and neck non- Hodgkin's Lymphoma

Nucleolar organizer regions (NORs) are loops of rDNA, which in human, occur on the short arms of five acrocentric chromosomes, namely, 13, 14, 15, 21 and 22. NORs are usually demonstrated by binding If their associated proteins (NORAPsO to silver (Ag+) ions. The reaction is called AgNORs. It has been determined that, the number and the size of NORs is related to the proliferative activity and grade of malignancy. This has led to the application of AgNOR method to a wide range of diagnostic problem cases, including breast, salivary glands and lung malignant neoplasms.The purpose of this study was to determine the value of AgNOR method in assessment of the grade of malignancy in non- Hodgkin's lymphoma of head & neck, which often is difficult and essentially important in relation to the prognosis and treatment.41 cases of paraffin embedded specimens of NHL, which were classified by working formulation system,were selected and then AgNORs method was applied on them.AgNORs were enumerated for all 41 cases of NHL (Standard Crocker).The mean AgNORs in 11 cases of low grade 15 cases of intermediate grade and 15 cases of high grade NHL was 1.66 (SEM= 0.098), 2.25 (SEM= 0.084) and 5.19 (SEM= 0.11), respectively.In analysis of variance and multiple comparisons, a significant difference was found between the three groups of NHL (P<0.000I).It is concluded that the AgNORs, as a reliable method, could be used in differentiation of low,intermediate and high grade NHL in head and neck area.