Journal of Dental Medicine

Evaluating the effect of bleomycin sulfate on oral keratotic lesions

Normal 0 false false false EN-US X-NONE AR-SA Non-removable Keratotic lesions are relatively prevalent in various types in oral mucosa. The treatment modality is often problematic and is done by using various specific regimens. Bleomycin was used in two primary studies with limited number of patients (N=9) . In current survey, more patients were recruited in a longer period of study. In fact, 50 leukoplakia and lichen planus patients were treated by local administration of belomycin in a 21 months follow-up period. Statistical analysis was done by using Kaplan meier and cox Regression methods. The obtained results showed that belomycin can remove many of these lesions and can prevent both chronic pattern and malignant changes of the lesions. As In 9 cases of leukoplakia, 2 cases of recurrence were recorded. According to statistical analysis, in case of complete treatment up to 11 months , the recurrence would not be possible. In 41 cases of lichen planus, recurrence rate was higher and after a longer period (17 months ) following complete treatment, recurrence was totally eliminated. In fact, Recurrence can be due to psychological conditions. To conclude, local administration of Bleomycin is recommended to use to treat Oral keratotic lesions and can act successfully based on current study's findings.

Evaluating the effects of chlorhexidine in periodontal treatments

M. Mosavi Jazi

Normal 0 false false false EN-US X-NONE AR-SA There has been many efforts to use antimicrobial agents in order to control microbes causing periodontal diseases since they play an integral role in the etiology of periodontal diseases. Chlorhexidine is a ADA approved antimicrobial and antiplaque mouthwash that is used to treat gingivitis. It acts by intense adhesion to the most sites of the oral cavity and is slowly released providing a long-lasting bactericidal environment that can result in lower plaque formation. Therefore, The risk of gingivitis and periodontal disease would be declined.

Studying manifestations of Kawasaki disease in head, neck and mouth in 5 hospitals of Tehran

Normal 0 false false false EN-US X-NONE AR-SA Kawasaki syndrome is an acute systemic disease found in 1967 by Kawasaki as " Mucocutaneous Lymphnode Syndrome". It was initially known as a benign children disease until it was found that it can cause sudden death in some patients. Still the etiology of the disease in unknown. 50% of the patients are under 2years and 80% are under 4 years while there are some cases of the disease in adults. Diagnosis criteria are 5-21 days antibiotic-resistant fever, conjunctivitis, changes in oral mucosa, cervical lymphadenopathy and dermal and mucosal lesions. In this study 48 (10 f/38 m)patients with Kawasaki disease were selected from 5 hospitals in Tehran. None had mentioned consanguineous marriage or familial history of the disease. The most incidence of the disease was found in summer and spring which confirmed the seasonal pattern of the disease.

Evaluating the effect of complete denture in correct pronunciation of speech sounds

Normal 0 false false false EN-US X-NONE AR-SA Although a full denture cab replace the teeth and their supporting structures , it commonly develops temporary speech problems that are resolved after a while. In this study, 70 patients were recruited from Prosthodontics department of Tehran and Isfahan dental schools. The patients were analyzed via special questionnaires and oral interview by gender, previous prosthesis and in 3 phases of edentulous, immediately after denture delivery and a week after delivery. Following data gathering and statistical analysis, it was found that "sh", "s"," Ch" sounds are the most and " m" is the least difficult sound to pronounce. The study results showed significant difference between 3 stages of denture usage. Also, the effect of previous prosthesis on speech was concluded while gender had not any relation with speech problems.

Normal 0 false false false EN-US X-NONE AR-SA Adenomatoid odontogenic tumor is a benign nonprevalent epithelial odontogenic tumor that induces odontogenic ectomesenchyme. The nature of AOT have always been questionable. In current study, as well as evaluating the prevalence of AOT cases in pathology department of Tehran university dental schools, some majorclinical features (gender, age, location, relation with aimpacted tooth) and histopathological features ( cyst wall relation, calcified mass or amyloid like fibrils) were thoroughly evaluated.

Assessing radiologic features of jawas and teeth in thalassemia: a case report

AR. Talaiepo

Normal 0 false false false EN-US X-NONE AR-SA Thalassemia is a chronic inherited anemia caused by abnormal hemoglobin synthesis in which some changes in bones, maxilla and zygomatic bone are developed. Radiologic view of cranial bones shows marrow space widening , cortical thinning , "Hair on End" view in cranium and "Honey comb" view in jaws. In present report, radiologic features of a typical thalassemic patient are mentioned and discussed.

Clinical and paraclinical Evaluation of locally administered phenytoin as an antimicrobial agent in periodontal surgeries

Y. Soleimani Shayeste

Normal 0 false false false EN-US X-NONE AR-SA As special microbial species are identified as etiologic factors for periodontal diseases and since conventional periodontal treatments could not eliminate these factors, Using Antimicrobial agents as alternatives to prevent post operation infections seems essential. In This study Phenytoin (Gel 10%) was used as an topical antimicrobial agent in periodontal surgeries. 21 patients with advanced periodontal disease were selected. Sampling was carried out before and after the surgery. The results showed that phenytoin can act effectively on gram positive and negative cocci while this concentration was not effective to eliminate opportunistic gram negative bacilli.

Treatment of temporomandibular joint sounds and clicks by occlusion adjustment

H. Benaz

Normal 0 false false false EN-US X-NONE AR-SA People are generally familiar with temporomandibular joint sounds and consider them as normal sounds that rarely needs treatment while unbalanced occlusion is one of the most important risk factors of TMJ disorder.TMD can cause Burning sensation in tongue and throat, tinnitus and pain. Unlike the other joints in the body, temporomandibular joint has avascular and fibrous articular interface in both sides. Joint sounds can be developed in one or both side in forms of clicking or grinding while at the beginning or at the end of mouth opening as well as at the beginning, in the middle or at the end of mouth closure. The recommended treatments involve occlusion therapy, psychotherapy, physiotherapy and medications.