Showing 199 results for Mohammad
Zahra Taghadomi Masoumi, Mohammad Reza Eshraghian, Mehdi Hedayati, Hamideh Pishva,
Volume 14, Issue 4 (3-2017)
Abstract
Background and Aim: Obesity is now recognized as the most prevalent metabolic disease worldwide.A decrease in resting energy expenditure (REE) may increase risk of obesity. This study was carried out to compare dietary, biochemical, anthropometric and body composition parameters and physical activity in obese women with a normal and those with a low REE.
Materials and Methods: A total of 49 subjects (women, 30-50 years old), were divided into three groups: group one (obese, n = 16) with a body mass index (BMI) of 28-39.9 and a normal REE, group 2 (obese, n = 17) with a BMI of 28-39.9 and a low REE, and group 3 (n = 16) with a normal BMI and a normal REE as the control group. Anthropometric measurements, body composition, REE and fasting blood lipid profile were determined in the 3 groups. In addition, dietary intakes and physical activity were assessed using valid questionnaires.
Results: There was no significant difference in body composition between the two obese groups. However, REE was significantly lower in the obese group with a lowREE than in the other 2 groups.Energy and macronutrient intakes and physical activity were not statistically different among the 3 groups. Neither was there any significant difference between the 2 obese groups (one with a normal and one with a low REE) as regards lipid profile.
Conclusion: The results of this study indicate that in some obese people the resting energy expenditure is much lower as compared to that in other obese people, although their body composition, age, sex, dietary intake, lipid profile and physical activity are not different.
Hashem Mohammadian, Jafar Kord Zanganeh, Parvaneh Kiani, Farzaneh Sharifat,
Volume 14, Issue 4 (3-2017)
Abstract
Background and Aim: Children are one of the most vulnerable groups in the population. Child abuse is a complex phenomenon with multiple causes. The purpose of this study was to do a confirmatory factor analysis of child abuse potential inventory among Ahvazi children in Ahvaz, Iran.
Materials and Methods: This was a descriptive-analytical study, including all Ahvazi primary school pupils aged 8-13 years in the academic year 2015-2016.
The sample size for confirmatory factor analysis was determined based on the number of questions per parameter.The variance was extracted on the basis of mean scores and
composite reliability for structural equation modeling was determined based on the first-order and second-order confirmatory factor analysisusing the LISREL software.
Results: Confirmatory factor analysis revealed a short form of the child abuse's original 3-actor structure, including the psychological, physical and neglect scales. The outcomes indicated that the firstorder model was a better fit for the data than the second.
Conclusion: It can be concluded that the Ahvazi version of the child abuse potential inventory questionnaire is acceptable from a psychometric point of view. We think it is essential to take into consideration the diversity of perspectives between parents and children in future research in this area.
Ali Mohammad Mosadeghrad, Ebrahim Jaafaripooyan, Mahmood Zamandi,
Volume 14, Issue 4 (3-2017)
Abstract
Background and Aim: Economic evaluation of health interventions is critical for efficient allocation of resources. The aim of this study was to critically review empirical studies on the cost-benefit of health interventions published over the last 40 years.
Materials and Methods: This study was carried out by searching seven databases (PubMed, Cochrane Database of Systematic Reviews, Web of science, Science Direct, Scopus, Springer Link, and SID) using appropriate keywords to find articles on the cost-benefit of health interventions published during 1975-2015. All the relatedretrieved articles were analyzed after quality assessment using a valid check list.
Results: A total of 33studies on the cost-benefit of health interventions during the last 40 years were included in the review; 39%, 37%, 21% and 3%of the studies had been conducted in Asia, America, Europe and Africa, respectively. The subjects dealt with in most ofthe studies (79%) were related to immunization, education, healthy nutrition and use of health technologies. Further analysis of the data showed mental health education, healthy nutrition, use of safety equipment while driving, vaccination, diagnostic and screening tests, and oral and dental healthto have considerable clinical and economic benefits.
Conclusion: The number of studies on the cost-benefit analysis of health interventions is increasing. Preventive and promotive interventions can help planners and policy-makers to better utilize the limited resources in the health sector aiming at promoting health of the people.
Seyed Mohammad Mojtahedzadeh, Kourosh Holakouie-Naieni, Shahrzad Nematollahi, Amir Hossein Mazarei,
Volume 15, Issue 1 (6-2017)
Abstract
Background and Aim: Considering the protection of, and safeguarding, the health of industrial workforce, this study was conducted to determine the prevalence of overweight and obesity in the personnel of Abadan oil refinery in the south-west of Iran and factors related to it.
Materials and Methods: The study included 721 oil refinery staff members randomly selected based on the yearly occupational health examination records. The information recorded included anthropometric measurements and blood test results; in addition, Breslow lifestyle and Global Physical Activity (GPAQ) questionnaires were completed for each subject.
Results: The mean body mass index (BMI) was 28.2 for men and 27.5 for women. The prevalence of obesity and overweight were 29.8% and 48.7%, respectively. Further analysis of the data showed that the prevalence rates were different between men and women; while 48.6% and 30.24% of the men suffered from overweight and obesity, respectively, the corresponding proportions among women were 50% and 15%. Overweight and obesity were associated with age, fasting blood glucose level, lipid profile and hypertension (in all cases p < 0.001).
Conclusion: The prevalence of overweight and obesity among Abadan oil refinery staff is higher as compared to the mean values in the general population in Iran or to personnel of other industries globally. Development and implementation of public educational programs with particular emphasis on high-risk individuals, such as middle-aged people and those with a low socioeconomic status, and focusing on healthy lifestyle and rotation shift workers can be effective, resulting in improvements in physical and general health of the personnel.
Mohammad Azimi, Yousef Adib, Hossein Matlabi,
Volume 15, Issue 1 (6-2017)
Abstract
Background and Aim: The content of the hygiene education and health promotion course in schools is crucial for raising the awareness of, and development of hygiene culture in, pupils. In this study we aimed to develop a hygiene education course with a fully suitable content.
Materials and Methods: In this research the content analysis technic using the "Shannon Entropy" method was used, in which data processing in discussing the content analysis is done with a new approach both quantitatively and qualitatively. In the information theory entropy is an index to measure the uncertainty which is expressed by a likelihood distribution. The content was investigated considering the respondents’ perspectives (all textbooks of elementary school sixth grade) and 12 main elements and 58 sub-elements related to hygiene education and health promotion.
Results: The results of content analysis based on the Shannon Entropy showed that the element of mental health with 732 items and physical activity with 735 items had the maximum frequencies, while the control and prevention of diseases with 6 items had the minimum frequency.
Conclusion: In the official textbooks some elements of health education are treated insufficiently or not at all, despite the fact that health is the most important factor in the progress of the society and a guarantee for survival. Thus, designing, implementation and management of the health component of national development plans are extremely vital.
Sara Shah Abadi, Mohammad Reza Saidi, Seyed Mohammad Mehdi Hazavehei, Saeid Bashiriyan, Manouchehr Karami, Behjat Marzbani,
Volume 15, Issue 2 (9-2017)
Abstract
Background and Aim: Cardiovascular diseases (CVDs) are a major cause of death worldwide. The objective of this study was to determine the most important behavioral (inadequate nutrition, low physical activity, smoking and alcohol consumption) and non-behavioral (stress, high blood sugar, dyslipidemia, hypertension and obesity) risk factors for CVD among CVD patients hospitalized in Kermanshah Heart Hospital. This was a needs assessment study aiming at designing interventions for reducing CVD risk factors.
Materials and Methods: In this cross-sectional study 402 CAD patients (60.4% males and 39.6% females) were selected by consecutive sampling from among those hospitalized in Imam Ali Hospital for the first time. Data were collected using the Iranian version of WHO Stepwise questionnaire and the patients’ files and analyzed using the SPSS-16 software.
Results: The mean (±SD) age of the patients was 54.2 (±8.8) years. About 73% of them had a poor diet and 46.5% had low physical activity; in addition, 36% of the men had consumed alcohol in the previous year and 26.1% were smokers. Non-behavioral risk factors were quite common too. The proportions of the patients suffering from diabetes, hypertension and overweight-plus-obesity and abdominal obesity were 49.3%, 48.0%, 54.7% and 61.0%, respectively. Finally, 43.3% of the patients had high stress, 31.0% were hypertriglyceridemic and in another 21% hypercholesterolemia was seen.
Conclusion: Based on the findings it can be concluded that, as compared to other risk factors, imbalanced nutrition was more prevalent common among the patients. Another major risk factor was obesity, particularly abdominal obesity. In addition, blood glucose disorders were more common than dyslipidemia.
Zahra Karimian, Fatemeh Atoof, Razieh Maasoumi, Mohammad Ali Besharat, Effat Sadat Merghati Khoei,
Volume 15, Issue 2 (9-2017)
Abstract
Background and Aim: Considering that the knowledge of, and attitude towards, sexuality is a key factor influencing sexual behavior, the main objective of this survey was to determine the bases of sexual knowledge and formation of attitude towards sexual script in women of reproductive age in Kashan City, Iran.
Materials and Methods: This was a cross-sectional study including 500 women of reproductive age referring to all health centers in Kashan Iran, selected by simple random sampling,. The data collection tool was the Sexual Knowledge and Attitude Scale (SKAS). The data were analyzed using descriptive statistics, correlation and regression model.
Results: The age range of the majority of the participants (51.9%) was 26-35 years, and the educational level of 39.9 % of them was high school education. The majority of them had a high level of sexual knowledge and attitude (51.4% and 62.9% respectively). The Pearson correlation test showed a significant positive correlation between knowledge and attitude of the women (p<0.05), and based on the multivariate regression analysis their knowledge score correlated with education and economic status and their sexual attitude scores with age and education.
Conclusion: The participating women were young and educated and their knowledge and attitude scores were high. However, they had erroneous attitudes and ideas, such as a feeling of shame and anxiety at intercourse, considering initiation in sexual relation responsibility of the man, and considering childbearing as the main purpose in sexual relations. It is essential to design and implement appropriate educational programs to help the women change their attitudes and ideas.
Farzaneh Sadat Mohammadi, Fatemeh Noorbakhsh, Sahar Honarmand Jahromi,
Volume 15, Issue 3 (12-2017)
Abstract
Background and Aim: In the last few decades co-trimoxazole, an antibacterial combination of trimethoprim and sulfamethoxazole, has been used for treatment of bacterial infections, but due to the vast usage of these drugs, resistant strains have appeared throughout the world. One of the reasons for resistance to co-trimoxazole is related to drf genes, which are responsible for trimethoprim resistance, while the sulfamethoxazole resistance is due to sulfonamide sul genes. The aim of this study was to investigate drug resistance and frequencies of resistance genes in gram-negative bacteria isolated from clinical specimens.
Materials and Methods: Clinical samples were collected from patients in Pars Hospital, Tehran, Iran, in which presence of gram-negative bacteria was confirmed by biochemical tests. Then antibiotic susceptibility tests were performed for 5 antibiotics by disk diffusion agar technic. DNA was extracted from bacteria resistant to co-trimoxazole, followed by PCR using specific primers for sul1, sul2, sul3, and drf7 genes.
Results: In the co-trimoxazole-resistant bacteria, 26%, 74%, 2% and 16% of the isolates contained sul1 gene, sul2 gene, sul3 gene and drf7 gene, respectively. Further analysis of the data showed that 51% of the isolates were resistant to gentamicin, 74% to ceftriaxone, 65% to ciprofloxacin and 3% to colistin. For resistance to trimethoprim only the drf 7 gene was used.
Conclusion: The results of this study show that in the isolates of co-trimoxazole-resistant gram-negative bacteria, the sul 2 gene has a major role in development of resistance to sulfonamides. In this study only the drf 7 gene was used to assess the resistance of trimethoprim, so we recommend to conduct studies also on other drf genes, so that the importance of each in resistance to co-trimoxazole can be determined.
Ali Mohammad Mosadeghrad, Ensiyeh Ashrafi,
Volume 15, Issue 4 (3-2018)
Abstract
Background and Aim: Quality management, as an organizational strategy, helps enhance hospital effectiveness and efficiency. This study aimed to examine the effect of a quality management model on the efficiency
of the respiratory intensive care unit in Labafijejad Hospital, Tehran in 2013-14.
Materials and Methods: This was a participatory action research conducted in
the respiratory intensive care unit in Labafijejad Hospital, Tehran in 2013-14. A quality improvement team was formed to implement the quality management system and promote working processes. The team identified and standardized working processes, determined the quality goals for the processes, and improved the processes based on the 10-stage Mosaddeghirad Quality Management model. Performance indicators of the unit (bed occupancy, bed turnover, and bed interval rates; patient average length of stay in the ward) were calculated and compared before and after the intervention.
Results: Implementing quality management brought about an increase of 2.8% and 19.2% in bed occupancy rate and bed turnover rate, respectively, as well as a decrease of 14.1% in patient average length of stay and a decrease of 35.6% in bed interval rate in the respiratory intensive care unit of the hospital.
Conclusion: Implementing quality management can increase the efficiency of the respiratory intensive care unit of a hospital. A suitable quality management system and the commitment of the hospital manager and staff can result in enhancement of efficenicy in a hospital.
Hashem Mohamadian, Mohammad Reza Jafari, Kambiz Ahmadi Anghali,
Volume 15, Issue 4 (3-2018)
Abstract
Background and Aim: The prevalence of chronic diseases can be reduced by correcting people's food habits. Therefore, the purpose of this study was to assess the explanatory power of the Expectation-Confirmation Model for the intention to continue fruit and vegetable consumption.
Materials and Methods: This descriptive-analytic study included 332 elderly people with a history of receiving health care services from 8 rural health centers and 40 health houses in Abadan city, Iran in the second half of 2015. Data were analyzed by path analysis and the multicolinearity test using LISREL8.8 and SPSS16 software, respectively.
Results: Less than half (48%) of the subjects consumed 1 to 3 servings of fruit and vegetable daily. The model used could explain 79% of the intention to continue fruit and vegetable consumption. Analysis of the data also showed positive associations between the intention to continue fruit and vegetable consumption and the following variables: self-efficacy (β = 0.09, P <0.01), perceived ease of use (β = 0.15, P <0.01), perceived benefits (β = 0.37, P <0.01), and satisfaction (β = 0.35, P <0.01); however, the perceived barriers had an inverse relationship with that intention (β=-0/2, P <0.01). From among the constructs of the mode, perceived benefits were the most effective factor influencing the intention to continue fruit and vegetable consumption (β=0.85, P <0.01).
Conclusion: The model used in this study is suitable for explaining the elderly people’s intention to continue fruit and vegetable consumption. It is recommended that policy-makers use appropriate strategies to increase the understanding of the benefits of eating fruits and vegetables by the elderly and, thus, sensitize them to increase their consumption through public campaigns and communication with the relevant organizations, families, etc.
Zahra Rezaeinasab, Mohammad Taghi Sheikhi, Fatemeh Jamilei Kohaneh Shahri,
Volume 15, Issue 4 (3-2018)
Abstract
Background and Aim: Self-immolation is the death of a life. It is seen in women who have suffered greatly in life for long years, lost patience totally and found no way out except self-immolation.
The aim of this study was to identify the epidemiologic pattern of women's self-immolation in Ilam Province, Iran during the period 2011-2016.
Materials and Methods: This was a descriptive study in which data were collected based on the files of women who had immolated themselves during the period 2015-2016 and analyzed using the SPSS software, the statistical tests being descriptive statistics.
Results: A total of 129 women, within the age range 11-95 years (mean 24 years), had immolated themselves during the 5-year period (53.5% in the age group 20-35 years), 73.6% of them being married and 77.5% housewives. The average body surface burn percentage was 70%, the range being 15-99%. Most cases of self-immolation had occurred in autumn and spring, mostly in the afternoon. The most common cause of self-immolation had been reported as unknown (38% of the cases), followed by mental disease and depression (30.2%) and family conflicts (17.1%), specially husband and wife conflicts.
Conclusion: Self-immolation is the unusual ending of a life. Young married women are more likely to get exposed to hardships and confusion in the course of family and community life. Depression is one of the most important causes of suicide, a consequence of issues such as violence and harassment by spouse and family, poverty, deprivation and destitution.
Strategies to reduce self-immolation would include comprehensive social support and protection against domestic violence against women, educationg women about techniques to control anger and reduce stress, and informing them about support centers.
Asiyeh Molaeifard, Mohammad Hossein Haghighi Zadeh, Hashem Mohammadian,
Volume 16, Issue 1 (6-2018)
Abstract
Background and Aim: Considering the lack of attention to the health promotion of adolescents due to their perception of being healthy in most countries of the world, we aimed to evaluate the predictors of adolescent health promoting lifestyle through path analysis based on IMB model.
Materials and Methods: This is a descriptive-analytic study on 400 high school students in Andimeshk city in two urban and rural areas. The sample size was obtained using the Cochran formula.They were selected by classified random sampling. In this study, demographic data, information about IMB model structures and student adherence to healthy lifestyle were collected in four areas nutrition, physical activity, stress control and responsibility. Correlation between total structures was analyzed using SPSS-23 software. Lisrel 8.5 software. Meanwhile, the relationships between variables were analyzed using Path analysis to fit and approve model fit model using LISREL8.8 software.
Results: All structures of IMB model had a Significant relationship with adolescent healthy lifestyle. Self-efficacy structure had the most predictive power. In general, self-efficacy variables, 75%, motivation 66%, and 50% knowledge had a positive and significant effect on behavior. This model was able to explain 71% of the variance in adolescent lifestyle behavior. Also, in this model, the level of self-efficacy variance (behavioral skills), 52%,, And motivation variance was explained 57%. Motivation and knowledge indirectly influenced the lifestyle behavior (behavior) by 55% and 50%, respectively.
Conclusion: The findings of this study showed that the IMB model has a good application for explaining and predicting the healthy lifestyle of adolescents. Accordingly, it is recommended that health planners apply the IMB model in order to promote adolescent lifestyle in this population.
Ali Mohammad Mosadeghrad, Seyed Shahabeddin Shahebrahimi, Mehdi Ghazanfari,
Volume 16, Issue 1 (6-2018)
Abstract
Background and Aim: Hospital accreditation is a systematic external evaluation of a hospital’s structures, processes and results (outputs/ outcome) by an independent professional accreditation body using pre-established optimum standards. This study aimed to examine the relationship between accreditation and hospital performance. In addition, the most important accreditation constructs affecting hospital performance were identified and ranked.
Materials and Methods: This descriptive, correlational and cross-sectional study was conducted using the data related to accreditation scores and nine performance indicators of 121 hospitals in 2014 and 123 hospitals in 2015 in Tehran province, Iran. Shannon entropy method was used for calculating the weights of the hospital indicators. Then, Feature Selection method in data mining was used to explore the relationship between accreditation scores and hospital indicators. Data were analyzed using IBM SPSS Modeler software. Analyses were carried out at the 0.05 significance level
Results: The mean of hospitals’ accreditation scores were 61.98% and 69.56% in 2014 and 2015 respectively. All performance indicators except the number of outpatients were increased in 2015 compared to 2014. There was no significant difference in the scores between 2014 and 2015 data. Hospitals’ accreditation scores were not associated with their performances. However, accreditation scores of leadership and management; accident and emergency; and procurement departments had the most effect on hospitals’ performance.
Conclusion: Accreditation was not correlated with hospital performance. Thus, improving accreditation system including standards, methods and surveyors and using quality management strategies in hospitals are necessary for improving hospital’ performance.
Marzieh Mohammadpour, Mehdi Yaseri, Mahmoud Mahmoudi, Rasoul Entezar Mahdi,
Volume 16, Issue 1 (6-2018)
Abstract
Background and Aim: Breast cancer is one of the most prevalent cancers in women and is the second cause of mortality due to cancer in women, with lung cancer being the first.
Materials and Methods: In this study we followed all the cases for 5 years, patients from West-Azerbaijan and East-Azerbaijan Provinces that diagnosed with breast cancer in 2009 and 2010 that attended to health cares. Using multivariate cure cox model for the influence of variables in this study.
Results: In this study 171 cases which suffering from breast cancer had the mean age of 55.9 ± 12.9 and the range of 23 to 89 years, in time of cancer diagnosis. Mean of patients follow-up was 51.7± 23.4 months with range of 11 days to 78 months. Overalls 52 death occurred and patient survival rate of 5 years was estimated 60. 6 percent. Eventually the two variables which are economic status and emergency hospitalization were found the two factors of pre-warning in long term survival of patient suffering from breast cancer.
Conclusion: Due to the findings, it seems using cure model in patients suffering from breast cancer was better than classical survival models.
Hosna Janjani, Mohammad Mehralian, Zahra Shamsizadeh, Zohreh Sadat Sangsefidi, Maryam Khashij,
Volume 16, Issue 1 (6-2018)
Abstract
Background and Aim: Paying attention to the hygiene and safety of food will have a great success for people around the world. In recent decades, due to mass production and food processing, the globalization of food trade, industrialization, etc., the prevalence of diseases associated with contaminated water and food is increasing. Therefore, the study of knowledge and attitude of people in this field have been a necessity and this research was conducted to investigate the knowledge and practice of people of Kermanshah city, Iran in relation to food hygiene and safety.
Materials and Methods: This was a cross-sectional study. Data were collected through questionnaires. 252 inhabitants of Kermanshah were randomly allocated by cluster sampling. Data analysis was performed using SPSS version 17 by Spearman and X2 test.
Results: Most of Kermanshah people were lack of proper knowledge and practice about food poisoning. Of these, 54% of people mistakenly thought that fully cooked foods also have microbes. In addition, 68.3% of the subjects did not have a proper health function regarding the consumption of fresh fruits and vegetables, so that they only cleaned it before consumption. Finally, the mean score of knowledge and practice was 11.62 ± 2.27 and 17.69 ± 1.59, respectively.
Conclusion: Considering the significant correlation between the level of knowledge and practice of the people living in Kermanshah about food safety, the necessity of conducting appropriate educational programs to increase the awareness and subsequently improve the performance of the related organs can upgrade status.
Somayeh Barmar, Masoumeh Alimohammadian, Seyed Alireza Sadjadi, Hasan Poustchi, Seyed Mostafa Hosseini, Mehdi Yasseri,
Volume 16, Issue 1 (6-2018)
Abstract
Background and Aims: Generalized Structural Equation Modeling (GSEM) is a family of statistical techniques utilized in the analysis of multivariate, categorical and ordinal data in order to measure latent variables and their connection with each other. The aim of this study is to consider the structure of data, and introducing GSEM to medical science researchers and presenting a practical example of in medical science researches.
Materials and Methods: An introduction to Structural Equation Modeling (SEM), along with its advantages and disadvantages was presented, and also GSEM and its all kind of forms was specified. An example to study hypertension risk factors in patients suffering from diabetes was carried out, which was a demonstration of using GSEM method for binary response variables. The data includes a random sample of 2716 people from Golestan province cohort studies.
Results: Age, body mass index, abdominal obesity, residence place, socioeconomic status, salt intake had direct effect on hypertension. Race, education, vitamin D and physical activity had direct and reverse effect on hypertension (p.value<0.05).
Discussion: Unlike SEM, the limitative hypothesis that our data should have a normal distribution do not needed in this model, also GSEM is powerful tool in the analysis of categorized data. Nevertheless this method cannot perform goodness of fit test, and adjustment and modification method of the model directly, and that they are some limitation in using this method.
Saeid Ebrahimi, Mohammad Khammarnia, Nasrin Porvazn, Mahnaz Karamipur, Hajar Jamshidzahi, Fatemeh Setoodezadeh, Mostafa Peyvand,
Volume 16, Issue 2 (9-2018)
Abstract
Background and Aim: The Internet is a strong and multimedia technology that meets the most basic needs of human beings; however, this new technology can have great negative effects on people's lives. This study aimed to determine the prevalence of Internet addiction and its relationship with quality of sleep and quality of life among students of Zahedan University of Medical Sciences.
Materials and Methods: This descriptive-analytical cross-sectional study was conducted in Zahedan in 2017.The study population included all the students of Zahedan University of Medical Sciences. A sample of 340 students were selected through stratified random sampling. Data were collected using three World Health Organization questionnaires, namely, quality of sleep, Internet addiction and quality of life questionnaires, and analyzed using SPSS (v22), the statistical tests being ANOVA and linear regression test and T-test.
Results: Data analysis showed that Internet addiction and the quality of life among the students were mild (43 ± 15) and desirable (78.4± 1.6), respectively. However, the sleep Quality Index for 282 students (82.9%) was not desirable. There were statistically significant associations (p<0.05) between the place of residence on the one hand and Internet addiction, quality of sleep and quality of life on the other.
Conclusion: Based on the findings it can be concluded that Internet addiction has a negative effect on the quality of sleep and quality of life of the students. The students need to pay more attention to the use of the Internet. It is also recommended that behavioral and cognitive intervention be designed and implemented aiming at teaching the students proper use of the computer and the Internet.
Alireza Heidari, Mohammad Arab, Kourosh Etemad, Behzad Damari, Mansoureh Lotfi,
Volume 16, Issue 2 (9-2018)
Abstract
Background and Aim: The purpose of phenylketonuria (PKU) screening is to assess the risk of, and prevent, the disease in the newborns likely inflicted with it. The aim of this study was to investigate why and how PKU screening was decided to be included in the national health agenda, initiated and implemented in Iran.
Materials and Methods: This qualitative study was conducted based on the Kingdon’s framework model in 2015. The participants were thirty-eight policy-makers, managers and researchers selected by purposeful sampling.Data were collected using semi-structured interviews and analyzed using framework analysis.
Results: The physical and mental disabilities, medical and maintenance costs and the need for rehabilitation services were examples of the problem stream. In addition, sampling based on the National Congenital Hypothyroidism Program and implementation feasibility at the national level were examples of the policy stream. Finally, pressure by the patients' families, the Scientific Children Association and executive managers were examples of the political will stream. When the three streams occurred simultaneously, health policy-makers agreed to implement the program and then was opened the window of opportunity.
Conclusion: Successful implementation of the National Phenylketonuria Screening Program in Iran has been the result of interactions among three streams, namely, nature of the problem, political will and optimal use of policy-makers of the window of opportunity opened.
Mehrasa Mohammadsadeghi, Niaz Mohammadzadeh Honarvar, Mostafa Qorbani, Anahita Mansouri, Fariba Kouhdani,
Volume 16, Issue 2 (9-2018)
Abstract
Background and Aim: Lipoprotein disorders are an integral component of type-2 diabetes mellitus (T2DM). Therefore, early diagnosis and treatment of lipid disorders can be beneficial in prevention and treatment of many complications associated with T2DM.The aim of this study wasto determine the effect of docosahexaenoic acid (DHA) supplementation on the serum levels of apolipoproteins (Apos) A1, A2, B48 and C3 in patients withT2DM.
Materials and Methods: In this 8-week randomized, double-blind, placebo-controlled clinical trial, 44 T2DMpatients were randomly assigned to either an experimental group (n=22, receiving daily 2.4 g DHA) or a placebo group (n = 22, receiving paraffin). The serum levels of AposA1, A2, B48 and C3 were measured in all the patients at the beginning and at the end of the period.
Results: There was a statistically significant increase in the mean serum level of ApoA1 in the DHA group (p = 0.014). In addition, a significant difference was observed in the serum level of ApoC3 after intervention between the DHA and placebo group (p=0.031). There were no significant differences between the two groups as regards the mean changes in serum levels of ApoA1, ApoA2, ApoB48 and ApoC3.
Conclusions: Dietary supplementation with docosahexaenoic acidhasno effects on the serum levels of apolipoproteins in patients with type-2 diabetes.
Kourosh Holakouie Naieni, Mohammad Ali Mansournia, Farzad Khodamoradi, Zahra Hosseinkhani, Mehdi Ranjbaran, Zohreh Foroozanfar, Yousef Alimohamadi, Solmaz Farrokhzad,
Volume 16, Issue 2 (9-2018)
Abstract
Background and Aim: Diabetes mellitus is one of the most prevalent and important health problems in the world.Considering the high prevalence of metabolic syndrome in diabetic patients and the potential effects of its components on HbA1C in these patients, the present study was conducted to determine the effect of metabolic syndrome components on HbA1C in type-2 diabetic patients.
Materials and Methods: This retrospective cohort study was conducted on 157 diabetic patients regularly referring to the Diabetes Control Center in Qazvin City during 2014, where complete data about theirmetabolic syndrome components, as well as HbA1C levels were available. The data were analyzed using multiple linear regression (α=0.05 for statistical significance).
Results: Based on the regression model, the effects of age, HDL-C and fasting blood glucose on HbA1C were statistically significant; the effects of other variables were nonsignificant. The R2value for the variables entered for prediction of HbA1C was found to be 0.45 (R2 = 45%).
Conclusion: Considering the significant relationship between some components of the metabolic syndrome such as HDL-C and fasting blood glucose on HbA1C in diabetic patients, it is essential to design and implement programs to reduce the level of HbA1C in these patients.
