A comparison of a single-dose and a seven-day treatment with Amoxicillin in asymptomatic bacteriuria in pregnancy

Niro Manesh , SH; Amiri , A; Ali yari , Sh

Volume 52, Issue 3 And 4 (30 1994) Tehran Univ Med J 1994, 52(3 And 4): 65-72 | Back to browse issues page

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Niro Manesh S, Amiri A, Ali yari S. A comparison of a single-dose and a seven-day treatment with Amoxicillin in asymptomatic bacteriuria in pregnancy. Tehran Univ Med J 1994; 52 (3 and 4) :65-72
URL: http://tumj.tums.ac.ir/article-1-1718-en.html

A comparison of a single-dose and a seven-day treatment with Amoxicillin in asymptomatic bacteriuria in pregnancy

SH Niro Manesh ^*

, A Amiri

, Sh Ali yari

Abstract: (12218 Views)

In this study, 1600 pregnant women who had referred to two prenatal clinics (Imam Khomeini and Mirza Kochek-Khan) were investigated. Ninety cases of asymptomatic bacteriuria were observed 77 of those cooperated with us until the end of our study. The subjects, who were within the 14-36 weeks of gestational age, were randomly divided into two groups: Group A received the medicine (Amoxicillin) in a single-dose (3gr.) and, group B received it within seven days (1gr. TDS). The rate of recovery (65% in group A and 56.8% in group B), based on chi-squared test, showed no significant difference (P=0.747%). According to the results of this study, we can conclude that single-dose treatment has the same value as a seven-day treatment and the advantages such as decreased total dose, lower cost, and a better patient compliance.

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