http://tumj.tums.ac.ir Tehran University of Medical Sciences Journal - Journal articles for year 1993, Volume 51, Number 2 Yektaweb Collection - https://yektaweb.com en 1993/5/11 http://journals.tums.ac.ir/tumj/browse.php?a_id=1732&sid=1&slc_lang=en During April, 1991 and September, 1993, eighteen patients with major thalassemia admitted to Shariati BMT center. Seventeen patients were transplanted were from HLA identical siblings and one from. his HLA identical father. Eleven of the donors were the known cases of minor thalassemia. The range of patients' age was within 3-10 years (with the average of 5 years and 11 months). Among them, seven patients were male and eleven were female. As the other international BMT centers, we classified our patients into three classes. Our criteria for this classification were hepatomegaly, ferretin, and liver fibrous 60% of our patients were put in class I and 40% in class II. All of our patients revealed a GVHD (severe graft vs. host disease) three weeks post-BMT as pruritus, diarrhea, and skin erythema especially in hands and feet. Two of the patients showed severe GVHD. One of the patients had chimerism after BMT. Although one year after BMT has passed, the patients is still depended on blood transfusion. One patient, despite graft rejection, died nine months post-BMT another one died after +70 due to GVHD. During 2.5 years, the overall graft survival rate was 88% in our center A Ghavamzadeh http://journals.tums.ac.ir/tumj/browse.php?a_id=1733&sid=1&slc_lang=en From hygienic and economical point of view, drug therapy and prophylaxy in infectious diseases are of great importance. After the world war II, a reduction in the efficacy of sulfonamide in the treatment of shigellosis was observed and later on it led to a survey on drug resistance and the way of its transmission. The aim of this survey, during which 100 cases of gram-negative bacteria were identified, is to study the drug resistance of this bacteria against five types of aminoglycosides by antibiotic sensitivity test (disc-diffusion). Out of 100 strains, 47% were resistant to gentamycin, 70% to kanamycin, 82% to streptomycin, 53% to tobramycin, and 8% to amikacin P Maleknejad http://journals.tums.ac.ir/tumj/browse.php?a_id=1734&sid=1&slc_lang=en Two hundred and twenty-eight patients who had developed Bell's palsy were investigated in a prospective study. Among them, 55% were male and 45% were female. The most common age of the disease onset was the third and beginning of the fourth decade of life. We found definite correlation between Bell's palsy, hypertension, and diabetes its recurrence rate was 9%. The most important complication was facial asymmetry that remained in 15% of the patients. The most common symptom prior to the development of facial palsy was the existence of pain in the back of ears and neck. Our patients responded well to 8 mg dexamethasone administered for a period of one week A Soltanzadeh http://journals.tums.ac.ir/tumj/browse.php?a_id=1735&sid=1&slc_lang=en Patients referred to Amir-Alam hospital, affiliated to Tehran University of Medical Sciences, were given anesthesia through two ways inhalationally (by means of sodium thiopenton) and intravenously (halothane+N2O). In this article, we discuss the results obtained from the patients' bronchoscopies. According to our study, inhalational anesthesia have had desirable effects since halothane has a positive inotropic effect, and N2O, due to its quick onset, has a high tendency to combine with halothane. Most of our cases were children who showed a high tolerance during an inhalational anesthesia. The overall mortality rate of intravenous anesthesia was two cases in contrast to that of the inhalational anesthesia which had none. It can be concluded that: 1) Although many cases necessitate bronchoscopy, their results are negative. 2) The incidence of bronchial bleeding, due to foreign bodies, is more in young boys than young girls. 3) There seems to be no difference in bronchoscopic results in different months of a year A Mahfouzi http://journals.tums.ac.ir/tumj/browse.php?a_id=1736&sid=1&slc_lang=en According to our experience, the best treatment for operable supracondylar fractures of the adults' humerus is surgery via open reduction following internal fixation and early mobilization. The preferred approach is olecranon because of its observable fragments of the fracture and easy fixation without damaging ulnar nerve and triceps muscle. In this article, we review several cases treated by this method whose results were quite satisfactory M Mirsaeidi http://journals.tums.ac.ir/tumj/browse.php?a_id=1737&sid=1&slc_lang=en The appropriate time for performing transfers in radial nerve palsy is somewhat a controversial matter. Brown suggested that it would be advisable to proceed early with the full component of tandon transfers when there is a questionable or poor prognosis for the nerve repair. For example, when there is a nerve gap of greater than 4 cm or when there is a large wound or extensive scarring or skin loss over the nerve. He recommended ignoring the nerve and proceeding directly to tandon transfer M Farzan http://journals.tums.ac.ir/tumj/browse.php?a_id=1738&sid=1&slc_lang=en Many years ago the treatment of sarcoma was radiotherapy up to 2000-4000 rad. This treatment was very complicated, due to producing neoplasm after radiotherapy. By this method of treatment of osteosarcoma, the rate of survival became about 20% (two years). The second method of treatment was chemotherapy for a period of 2-5 weeks that amputation was performed afterwards. By chemotherapy, the rate of being alive reached up to 25-27% (five years). Right now, the best treatment for sarcoma is limb salvage. In our report, the chance of being alive in chondrosarcoma was about four years. This was nearly the same as that of the other institutes in the world especially in America, Europe, and Japan. The rate of recurrence was also more than that from different parts of the world. The survival rate in osteosarcomatic patients was about two years less for males the females, and it was more in tall people than short ones. The survival rate of the patients with giant cell tumor was more than osteosarcoma up to five years, and it has no recurrence or metastasis M Motamedi http://journals.tums.ac.ir/tumj/browse.php?a_id=1739&sid=1&slc_lang=en This is a report of a case study on 234 patients with impetigo who referred to Razi Dermatology Hospital from April to November, 1989. Treatment was started immediately after obtaining direct smear and performing culture and antibiotic sensitivity test. The most common organism responsible for impetigo was the coagulase-positive staphylococcus (71%). In 13.7% of the cases, the coagulase-negative staphylococcus was grown on culture media, but none of the cultures showed streptococcus as the main organism. Treatment was started with oral penicillin V, oral erythromycin, benzathine penicillin G injection, oral cephalexin, and topical fuccidin. Clinical and bacteriological evaluation after 3-7 days showed that it is preferable to use oral cephalexin instead of other protocols such as oral erythromycin, which has previously been the drug of choice for impetigo. In addition, topical fuccidin with a 75% curative rate was the first drug for treatment, with the same effect as the oral cephalexin P Mansouri http://journals.tums.ac.ir/tumj/browse.php?a_id=1740&sid=1&slc_lang=en This investigation aims to diagnose the incidence and complications of labor and delivery of grandmultiparity (GMP) in Tehran. The results obtained are as follows: 1) The incidence of high parity was 11%. 2) 47.3% of GMP women were within the age range of 14-16 years at their marriage time. 3) The infants of GMP women were born with lower apgar score than the infants of the control group. 4) The incidence of fetal distress was estimated up to 31.8%. 5) In 1.8% of cases, infants showed to have born with Down's syndrome. 6) Other congenital abnormalities showed no significant differences between the two groups. 7) The rate of stillbirth in GMP women was higher than that of the control group (4.5% vs. 1%). 8) Cesarean section performed in 25.5% of GMP women in comparison to 14.5% in control group Sh Niroumanesh http://journals.tums.ac.ir/tumj/browse.php?a_id=1741&sid=1&slc_lang=en IgD myeloma is very rate. It differs from multiple myeloma of other classes in several aspects and its laboratory diagnosis may be difficult, as total plasma protein concentration is often normal, and a paraprotein peak may not be easily demonstrable by the conventional electrophoretic techniques. We report here two cases of IgD myeloma investigated in this laboratory. Immunochemical, biochemical, and hematological studies were carried out: Serum total protein values were within normal range. Quatitation of serum immunoglobulins revealed a decrease in the level of IgG, IgA, and IgM. Bence Jones proteinuria of l type was present in both patients. Serum immunoelectrophoresis, using specific antisera, showed the presence of IgD l paraprotein the diagnosis of IgD myeloma was made after further investigations. Our findings indicate that all patients who have been suspected to have multiple myeloma should be investigated for IgD and IgE myeloma M Mirahmadian