Hedayat A, Bastan Hagh M H, Bavandi F,
Volume 61, Issue 4 (15 2003)
Abstract
Intra-operative measurement of intact Parathyroid hormone (iPTH) using a rapid assay technique is useful as an aid in determining adequacy of resection and leads to reduce re-operative cases.
Materials and Methods: In a prospective case series study, PTH level determined before and after (intra-operative and one day after) Parathyroidectomy in 34 patients with primary hyperthyroidism that refer to Shariati hospital during 18 months between year 2000 and 2001.
Results: The average PTH levels before and after parathyroidectomy were 563 pgr/lit and 121 pgr/lit. All patients had significant decrease in PTH levels after Parathroidectomy (mean = 78%). One day after operation, this level decreased to 42 pgr/lit (mean = 87% decrease compared with before operation)
Conclusion: In this study, like the same other studies from other countries there was significant decrease in PTH levels in rapid intra-operative assay that can demonstrate the reliability of PTH monitoring for intra-operative management and overall operative success rates.
