Tehran University Medical Journal
مجله دانشکده پزشکی، دانشگاه علوم پزشکی تهران
Tehran Univ Med J
Medical Sciences
http://tumj.tums.ac.ir
1
admin
1683-1764
1735-7322
10.18869/acadpub.tumj
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000
fa
jalali
1402
2
1
gregorian
2023
5
1
81
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online
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بررسی رابطه بین سطح سرمی چربی مادران باردار و وزن موقع تولد جنین: یک گزارش کوتاه
Investigating the relationship between the serum fat level of pregnant mothers and the birth weight of the fetus: a brief report
مقاله اصیل
Original Article
<div><span style="font-family:yekanYW;"><span style="font-size:12pt"><span style="line-height:102%"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><i><span lang="FA" style="font-size:10.0pt"><span style="line-height:102%">زمینه و هدف:</span></span></i></b><span lang="FA" style="font-size:10.0pt"><span style="line-height:102%"> مطالعه حاضر با هدف بررسی، تعیین رابطه سطح سرمی چربی مادران باردار و وزن موقع تولد جنین انجام شد.</span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:102%"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><i><span lang="FA" style="font-size:10.0pt"><span style="line-height:102%">روش بررسی:</span></span></i></b> <span lang="AR-SA" style="font-size:10.0pt"><span style="line-height:102%">پژوهش توصیفی-مقطعی حاضر از فروردین تا اسفند 1398 روی 170 زن باردار مراجعهکننده به درمانگاههای دانشگاه علوم پزشکی کرمان انجام شد و متغیرهای مورد نظر در طول بارداری (سن، </span></span><span dir="LTR" style="font-size:8.0pt"><span style="line-height:102%">BMI</span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="line-height:102%">، وزن و دفعات حاملگی و میزان افزایش وزن در بارداری و پروفایل لیپید و قندخون) اندازهگیری گردید و نتایج با استفاده از </span></span><span dir="LTR" style="font-size:8.0pt"><span style="line-height:102%">SPSS software, version 20 (IBM SPSS, Armonk, NY, USA)</span></span><span style="font-size:10.0pt"><span style="line-height:102%"> تحلیل گردید.</span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:102%"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><i><span lang="FA" style="font-size:10.0pt"><span style="line-height:102%"><span style="letter-spacing:-.1pt">یافتهها:</span></span></span></i></b> <span lang="AR-SA" style="font-size:10.0pt"><span style="line-height:102%"><span style="letter-spacing:-.1pt">نتایج مطالعه نشان داد که سطح خونی تری</span></span></span><span lang="FA" style="font-size:10.0pt"><span style="line-height:102%"><span style="letter-spacing:-.1pt"></span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="line-height:102%"><span style="letter-spacing:-.1pt">گلیسیرید و کلسترول با وزن موقع تولد نوزاد ارتباط دارند. با افزایش تعداد دفعات حاملگی (001/0</span></span></span><span dir="LTR" style="font-size:8.0pt"><span style="line-height:102%"><span style="letter-spacing:-.1pt">P=</span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="line-height:102%"><span style="letter-spacing:-.1pt">) و افزایش تعداد نوزاد زنده (001/0</span></span></span><span dir="LTR" style="font-size:8.0pt"><span style="line-height:102%"><span style="letter-spacing:-.1pt">P=</span></span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="line-height:102%"><span style="letter-spacing:-.1pt">) وزن موقع تولد نوزاد افزایش مییابد.</span></span></span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:102%"><span style="direction:rtl"><span style="unicode-bidi:embed"><b><i><span lang="FA" style="font-size:10.0pt"><span style="line-height:102%">نتیجهگیری:</span></span></i></b> <span lang="AR-SA" style="font-size:10.0pt"><span style="line-height:102%">نتایج حاصل از مطالعه نشان داد که با افزایش کلسترول و تریگلیسیرید خون مادر باردار، وزن موقع تولد نوزاد افزایش مییابد. همچنین افزایش </span></span><span dir="LTR" style="font-size:8.0pt"><span style="line-height:102%">HDL</span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="line-height:102%"> و </span></span><span dir="LTR" style="font-size:8.0pt"><span style="line-height:102%">LDL</span></span><span lang="AR-SA" style="font-size:10.0pt"><span style="line-height:102%"> خون مادر باردار باعث افزایش وزن موقع تولد نوزاد نمیشود. پیشنهاد میشود مطالعه با حجم نمونه بزرگتر جهت بررسی همه فاکتورهای موثر در وزن نوزاد انجام شود.</span></span></span></span></span></span></span></div>
<div><span style="font-size:12pt"><span style="line-height:130%"><span new="" roman="" style="font-family:" times=""><b><i><span style="font-size:10.0pt"><span style="line-height:130%">Background:</span></span></i></b><span style="font-size:10.0pt"><span style="line-height:130%"> birth weight is associated with neonatal mortality and morbidity .In recent studies, fetal growth is related to the risk of developing type two diabetes and cardiovascular disease in later life. The mother’s nutrition and metabolism are major determinants of fetal growth. Some complications of low birth weight are hypocalcemia, hypoglycemia, intrauterine death. Any substance or hormone that can cross the placenta may affect the fetal growth and birth weight, including the maternal lipid during pregnancy. The effect of gestational diabetes mellitus on neonatal birth weight has been documented. Lipids and amino acids usually are not considered in the clinical management of pregnancy because there is less known about the role of these nutrients in the well-being of the pregnancy. This study aimed to determine the relationship between levels of serum lipids in pregnancy and fetal birth weight.</span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:130%"><span new="" roman="" style="font-family:" times=""><b><i><span style="font-size:10.0pt"><span style="line-height:130%">Methods:</span></span></i></b><span style="font-size:10.0pt"><span style="line-height:130%"> This descriptive cross-sectional study was performed on 170 pregnant women referred to Kerman medical university clinics in Iran from March 2019 to April 2020. After explaining the objectives of the study and gaining informed consent from the individuals, the maternal lipid profile during the first trimester of pregnancy, was measured within the first visit through a sample taken from the maternal blood. Pregnant women were monitored during pregnancy, and the variables were measured (Age, BMI, weight, frequency of pregnancy, weight gain in pregnancy, lipid and blood glucose profiles). The results of the samples were analyzed using SPSS software, version 20 (IBM SPSS, Armonk, NY, USA).</span></span></span></span></span><br>
<span style="font-size:12pt"><span style="line-height:130%"><span new="" roman="" style="font-family:" times=""><b><i><span style="font-size:10.0pt"><span style="line-height:130%">Results:</span></span></i></b><b> </b><span style="font-size:10.0pt"><span style="line-height:130%">The results indicated that the newborn weight increases with an increment in the maternal blood cholesterol (P=0.001) and triglyceride (P=0.001) levels. In addition, it was found that the increasing HDL (P=0.867) and LDL (P=0.803) levels of the pregnant women’s blood, does not lead to the birth weight increase of the infants.</span></span><span dir="RTL" lang="AR-SA" style="line-height:130%"><span style="font-family:"B Lotus""></span></span></span></span></span></div>
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<div><span style="font-size:12pt"><span style="line-height:130%"><span new="" roman="" style="font-family:" times=""><b><i><span style="font-size:10.0pt"><span style="line-height:130%">Conclusion:</span></span></i></b><span style="font-size:10.0pt"><span style="line-height:130%"> Results of our study generally indicate that triglyceride and cholesterol levels are related to fetal birth weight. Studies with high sample sizes are recommended to investigate all neonatal weight gain variables.</span></span><span dir="RTL" lang="AR-SA" style="line-height:130%"><span style="font-family:"B Lotus""></span></span></span></span></span></div>
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بارداری, پروفایل چربی خون مادر, وزن موقع تولد نوزاد.
birth weight, pregnancy, lipid.
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154
http://tumj.tums.ac.ir/browse.php?a_code=A-10-3666-637&slc_lang=other&sid=1
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