<?xml version="1.0" encoding="utf-8"?>
<journal>
<title>Tehran University Medical Journal</title>
<title_fa>مجله دانشکده پزشکی، دانشگاه علوم پزشکی تهران</title_fa>
<short_title>Tehran Univ Med J</short_title>
<subject>Medical Sciences</subject>
<web_url>http://tumj.tums.ac.ir</web_url>
<journal_hbi_system_id>1</journal_hbi_system_id>
<journal_hbi_system_user>admin</journal_hbi_system_user>
<journal_id_issn>1683-1764</journal_id_issn>
<journal_id_issn_online>1735-7322</journal_id_issn_online>
<journal_id_pii></journal_id_pii>
<journal_id_doi>10.18869/acadpub.tumj</journal_id_doi>
<journal_id_iranmedex></journal_id_iranmedex>
<journal_id_magiran></journal_id_magiran>
<journal_id_sid>000</journal_id_sid>
<journal_id_nlai>000</journal_id_nlai>
<journal_id_science>000</journal_id_science>
<language>fa</language>
<pubdate>
	<type>jalali</type>
	<year>1391</year>
	<month>3</month>
	<day>1</day>
</pubdate>
<pubdate>
	<type>gregorian</type>
	<year>2012</year>
	<month>6</month>
	<day>1</day>
</pubdate>
<volume>70</volume>
<number>3</number>
<publish_type>online</publish_type>
<publish_edition>1</publish_edition>
<article_type>fulltext</article_type>
<articleset>
	<article>


	<language>fa</language>
	<article_id_doi></article_id_doi>
	<title_fa>نتایج آنژیوپلاستی و تعبیه استنت کاروتید در بیماران با تنگی پرخطر کاروتید گردنی برای جراحی اندآرترکتومی کاروتید</title_fa>
	<title>Short- and long-term outcomes of angioplasty and stenting for high-risk extracranial carotid stenosis in carotid endarterectomy</title>
	<subject_fa></subject_fa>
	<subject></subject>
	<content_type_fa></content_type_fa>
	<content_type></content_type>
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&lt;w:dontflipmirrorindents&gt; &lt;w:overridetablestylehps&gt; &lt;/w:overridetablestylehps&gt;&lt;/w:dontflipmirrorindents&gt;&lt;/w:enableopentypekerning&gt;&lt;/w:splitpgbreakandparamark&gt;&lt;/w:dontgrowautofit&gt;&lt;/w:useasianbreakrules&gt;&lt;/w:wraptextwithpunct&gt;&lt;/w:snaptogridincell&gt;&lt;/w:breakwrappedtables&gt;&lt;/w:compatibility&gt; &lt;w:browserlevel&gt;MicrosoftInternetExplorer4&lt;/w:browserlevel&gt; &lt;m:mathpr&gt; &lt;m:mathfont m:val=&quot;Cambria Math&quot;&gt; &lt;m:brkbin m:val=&quot;before&quot;&gt; &lt;m:brkbinsub m:val=&quot;--&quot;&gt; &lt;m:smallfrac m:val=&quot;off&quot;&gt; &lt;m:dispdef&gt; &lt;m:lmargin m:val=&quot;0&quot;&gt; &lt;m:rmargin m:val=&quot;0&quot;&gt; &lt;m:defjc m:val=&quot;centerGroup&quot;&gt; &lt;m:wrapindent m:val=&quot;1440&quot;&gt; &lt;m:intlim m:val=&quot;subSup&quot;&gt; &lt;m:narylim m:val=&quot;undOvr&quot;&gt; &lt;/m:narylim&gt;&lt;/m:intlim&gt;&lt;/m:wrapindent&gt;&lt;/m:defjc&gt;&lt;/m:rmargin&gt;&lt;/m:lmargin&gt;&lt;/m:dispdef&gt;&lt;/m:smallfrac&gt;&lt;/m:brkbinsub&gt;&lt;/m:brkbin&gt;&lt;/m:mathfont&gt;&lt;/m:mathpr&gt; 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&lt;strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;زمینه و هدف:&lt;/span&gt;&lt;em&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;/em&gt;&lt;/strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;درمان انتخابی استاندارد بیماران دچار تنگی قابل توجه کاروتید، اندآرترکتومی کاروتید می&#8204;باشد. درمان جایگزین انتخابی در بیمارانی که دچار دیگر بیماری&#8204;های طبی همراه (به&#8204;عنوان بیماران پرخطر) باشند، آنژیوپلاستی و تعبیه استنت کاروتید می&#8204;باشد. در این مطالعه قصد داریم پیامد درمانی زودرس و دیررس حاصل از آنژیوپلاستی و تعبیه استنت کاروتید را در این بیماران بررسی کنیم. &lt;/span&gt;&lt;/w:donotpromoteqf&gt;&lt;/w:validateagainstschemas&gt;&lt;/w:punctuationkerning&gt;&lt;/w:trackformatting&gt;&lt;/w:trackmoves&gt;&lt;/p&gt;

&lt;p dir=&quot;rtl&quot; style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;روش بررسی:&lt;/span&gt;&lt;em&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;/em&gt;&lt;/strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;82 بیمار مراجعه&#8204;کننده به بیمارستان&#8204;های بقیه&#8204;الله &lt;/span&gt;&lt;span style=&quot;font-size: 9pt&quot;&gt;(عج)&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt; و جماران تهران که در طی سال&#8204;های 89-1387 به&#8204;علت تنگی قابل توجه شریان کاروتید&lt;a name=&quot;OLE_LINK6&quot;&gt;&lt;/a&gt;&lt;a name=&quot;OLE_LINK5&quot;&gt;&lt;span&gt; (تنگی &lt;/span&gt;&lt;/a&gt;&lt;/span&gt;&lt;span&gt;&lt;span&gt;&lt;span style=&quot;font-size: 8pt&quot;&gt;&amp;ge;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;50% در بیماران با علامت و تنگی &lt;/span&gt;&lt;span style=&quot;font-size: 8pt&quot;&gt;&amp;ge;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt; 80-70% در بیماران بدون علامت) &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;و به&#8204;علت ریسک بالای جراحی کاندیدای استنت&#8204;گذاری گردیده بودند وارد مطالعه شدند. تمامی بیماران توسط جراح و متخصص بیهوشی از لحاظ پرخطر بودن برای اندآرترکتومی کاروتید مورد تایید قرار گرفتند. متوسط زمان پی&#8204;گیری پس از استنت&#8204;گذاری بیماران 9/15 ماه بود.&lt;strong&gt; &lt;/strong&gt;&lt;/span&gt;&lt;/p&gt;

&lt;p dir=&quot;rtl&quot; style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;یافته&#8204;ها:&lt;/span&gt;&lt;/strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;مطالعه حاضر به روش مقطعی- توصیفی بر روی 54 بیمار مرد (9/65%) و 28 بیمار زن (1/34%) انجام گرفت. سن متوسط بیماران 2/9&lt;/span&gt;&lt;span style=&quot;font-size: 8pt&quot;&gt;&amp;plusmn;&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;7/69 سال بود. آنژیوپلاستی و تعبیه استنت کاروتید در 79 بیمار (3/96%) موفقیت&#8204;آمیز بود. متعاقبا 3/7% مرگ، 1/6% &lt;/span&gt;&lt;span style=&quot;font-size: 8pt&quot;&gt;Stroke&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;، 9/4% &lt;/span&gt;&lt;span style=&quot;font-size: 7pt&quot;&gt;TIA&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;، 9/4% &lt;/span&gt;&lt;span style=&quot;font-size: 7pt&quot;&gt;MI&lt;/span&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt; بعد از انجام آن مشاهده گردید.&lt;/span&gt;&lt;/p&gt;

&lt;p dir=&quot;rtl&quot; style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;نتیجه&#8204;گیری:&lt;/span&gt;&lt;em&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;&amp;nbsp;&lt;/span&gt;&lt;/em&gt;&lt;/strong&gt;&lt;span style=&quot;font-size: 10pt&quot;&gt;به&#8204;نظر می&#8204;رسد آنژیوپلاستی و تعبیه استنت کاروتید روش درمانی موثر، قابل اطمینان و از لحاظ تکنیکی بسیار موفقیت&#8204;آمیز باشد. هم&#8204;چنین این مداخله ثابت نمود که استفاده از روش&#8204;درمانی آنژیوپلاستی و تعبیه استنت کاروتید با میزان شیوع بسیار پایین عوارض حین و بعد عمل همراه است.&lt;/span&gt;&lt;/p&gt;
</abstract_fa>
	<abstract>&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Background&lt;/strong&gt;: Carotid endarterectomy (CEA) is a standard method for patient with significant carotid stenosis but direct surgical repair via carotid endarterectomy may not be a good option in some patients because of the overall health status that may make the surgery too risky. Carotid angioplasty and stenting (CAS), is a relatively new procedure for the treatment of carotid artery disease in patients who may not be fit enough to undergo surgery. In this investigation, we determined short- and long-term outcomes of stent angioplasty in high-risk patients for whom the risk of perioperative morbidity and mortality is high.&lt;/p&gt;

&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Methods&lt;/strong&gt;: We have followed 82 consecutive symptomatic patients with a &amp;ge;50% and asymptomatic patients with a &amp;ge;70%- 80% carotid stenosis within 15.9 months of angioplasty and stenting in Baqiyatallah and Jamaran hospitals from 2008-2010. All the patients were considered poor surgical candidates by experienced surgeons and anesthesiologists upon pre-surgical consultation.&lt;/p&gt;

&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Results&lt;/strong&gt;: This descriptive cross-sectional study was performed on 28 women and 54 men with a mean age of 69.7&amp;plusmn;9.2 years. The procedure was technically successful in 79 (96.3%) cases. There were 6 (7.3%) deaths, 5 (6.1%) strokes, 4 (4.9%) MIs and 4 (4.9%) TIAs during the follow-up period.&lt;/p&gt;

&lt;p style=&quot;text-align: justify&quot;&gt;&lt;strong&gt;Conclusion&lt;/strong&gt;: The clinical results during the short available follow-up period suggested stent angioplasty to be useful, effective, reliable and safe in the treatment of significant cervical carotid stenosis in high-risk patients. Further analytical investigations with longer follow-up periods for predicting risk factors are recommended.&lt;/p&gt;
</abstract>
	<keyword_fa>سکته مغزی,تعبیه استنت کاروتید,اندآرترکتومی کاروتید,تنگی شریان کاروتید</keyword_fa>
	<keyword>Angioplasty,carotid endarterectomy,carotid stenosis,stenting,stroke</keyword>
	<start_page>162</start_page>
	<end_page>168</end_page>
	<web_url>http://tumj.tums.ac.ir/browse.php?a_code=A-10-98-4&amp;slc_lang=fa&amp;sid=1</web_url>


<author_list>
	<author>
	<first_name>Kazemi-Saleh</first_name>
	<middle_name></middle_name>
	<last_name>Davood</last_name>
	<suffix></suffix>
	<first_name_fa>داوود</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>کاظمی صالح</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code></code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Interventional Cardiologist, Faculty of Medicine and Cardiovascular Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa>مرکز تحقیقات قلب و عروق، دانشگاه علوم پزشکی بقیه الله  ، تهران، ایران</affiliation_fa>
	 </author>


	<author>
	<first_name>Karimi</first_name>
	<middle_name></middle_name>
	<last_name>Heidar</last_name>
	<suffix></suffix>
	<first_name_fa>حیدر</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>کریمی</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code></code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Cardiology, Baqiyatallah University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa>گروه قلب و عروق    دانشگاه علوم پزشکی بقیه الله  ، تهران، ایران</affiliation_fa>
	 </author>


	<author>
	<first_name>Saburi</first_name>
	<middle_name></middle_name>
	<last_name>Amin</last_name>
	<suffix></suffix>
	<first_name_fa>امین</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>صبوری</last_name_fa>
	<suffix_fa></suffix_fa>
	<email>aminsaburi@yahoo.com</email>
	<code></code>
	<orcid></orcid>
	<coreauthor>Yes
</coreauthor>
	<affiliation>Researcher, Chemical Injury Research Center and Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa>مرکز تحقیقات آسی بهای شیمیایی و مرکز تحقیقات بهداشت و تغذیه دانشگاه علوم پزشکی بقیه الله  ، تهران، ایران</affiliation_fa>
	 </author>


	<author>
	<first_name>Niknam</first_name>
	<middle_name></middle_name>
	<last_name>Z</last_name>
	<suffix></suffix>
	<first_name_fa>زهرا</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>نیکنام</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code></code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Neurology, Baqiyatallah University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa>گروه داخلی مغز و اعصاب دانشگاه علوم پزشکی بقیه الله  ، تهران، ایران</affiliation_fa>
	 </author>


	<author>
	<first_name>Pishgoo</first_name>
	<middle_name></middle_name>
	<last_name>Bahram</last_name>
	<suffix></suffix>
	<first_name_fa>بهرام</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>پیشگو</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code></code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Interventional Cardiologist, Faculty of Medicine and Cardiovascular Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa>مرکز تحقیقات قلب و عروق، دانشگاه علوم پزشکی بقیه الله  ، تهران، ایران</affiliation_fa>
	 </author>


	<author>
	<first_name>Karimi</first_name>
	<middle_name></middle_name>
	<last_name>Pedram</last_name>
	<suffix></suffix>
	<first_name_fa>پدرام</first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa>کریمی</last_name_fa>
	<suffix_fa></suffix_fa>
	<email></email>
	<code></code>
	<orcid></orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Medical Student, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
	<affiliation_fa>دانشجوی پزشکی، دانشگاه علوم پزشکی تهران  ، تهران، ایران</affiliation_fa>
	 </author>


</author_list>


	</article>
</articleset>
</journal>
