Background & Aim: Bacterial vaginosis is characterized by an imbalance in vaginal natural discharges due to an overgrowth of anaerobic bacteria as well as a concomitant decrease in the number of lactobacilli and increase in vaginal PH to more than 4.5. Bacterial vaginosis increases the risk of pelvic inflamatory disease, postoperative infection following hysterectomy, cervix abnormal cytology and preterm birth. Microbial resistance and a growing tendency to move toward "natural therapies" have led to increase interests in non-antibiotic treatments for bacterial vaginosis. This study aimed to compare the effects of Lactobacillus acidophilus suppository and Metronidazol vaginal tablet on treatment of bacterial vaginosis.

Methods & Materials: In a double-blind, paralled randomized clinical trial, 40 out of 300 participants were included in the study from an out-patient private gynaecology clinic in Tabriz, Iran. The participants were randomly allocated to two treatment groups of Lactobacilli suppository and Metronidazol vaginal tablet.

Results: The cure rate for the Metronidazol group and the Lactobacilli supository group were 100 and 75 per cents, respectively.

Conclusion: According to the results of this study, Metronidazol was more effective in treatment of bacterial vaginosis than the Lactobacilli suppository. A combination of these medications are suggested for resistant to treatment cases.

Background & Aim: Maternal request for caesarean section due to fear of normal vaginal delivery (NVD) is one of the main reasons for the high rate of caesarean section. This study aimed to compare the fear of NVD and type of delivery between two groups of pregnant women attended childbirth preparation classes (CPC) and women received routine prenatal care (RPC).

Methods & Materials: In this prospective cohort study, 202 Primigravid women attended healthcare centers for prenatal care services in the East of Guilan were selected using convenient sampling in 2013-2014. Fear of NVD was assessed using a childbirth attitude questionnaire at two stages (before attending CPC or receiving RPC, then at the third trimester of pregnancy). Both groups were followed up to the delivery time. Data were analyzed using inferential and descriptive statistics (Chi square, paired t-test, ANOVA, t-test) through SPSS v.16. P<0.05 was considered as significant.

Results: There was no significant difference (P=0.23) in the mean score of fear of NVD between two groups before attending CPC (35.59±8.78) and receiving RPC (37.08±9.08). The comparison of the mean score of fear of NVD between two groups at the third trimester of pregnancy showed a significant reduction (P<0.001) in the first group (32.30±8.31) than in the second group (37.29±9.55). A significant difference was also observed between two groups in the rate of NVD (P=0.002).

Conclusion: Results confirm the importance of CPC in decreasing fear of NVD and increasing the rate of NVD in primigravid women attended these classes. Therefore, women’s attendance at CPC is recommended to be encouraged.