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This research is a descriptive- analytic study which has been conducted inorder to determine the degree of tuberculous patients knowledge of their tubereulosis disease and its relation to therapeutic regimen in Tehran TB control centers.In this research , 120 tuberculous patients calling on tuberculosis control centers in Tehran andbeing under drug therdpyfor about 2-9 months were selected as subjects in this research . sampling hasbeeneasyaswellashaphazardlydatawasgatheredthroughaquestionnaire. the questionnaire used in this research includes 3 section . After gathering the data, descriptive and deductive statistics used in order to analyse the data more over, chi-square and fisher Exact Test used to study the relation between the knowledge variables and therapeutic regimen in accordance with demographic characteristics and chouporof coefficient used to determine correlation intensity.Research results concerning units under investigation showed that the majority on insufficient knowledge of their disease which the minority (%18) had a sufficient knowledge, the majority (%62) had a proper drug therapy while the minority (%1) did not the majority (%72) did not Take a efficient diet while the minority (%2) took a proper diet, the majority (%58) medium personal Health care while the minority (%15) folllowed a good personal health care, and generally the majority (%47) had a medium therapeutic regimen while the minority (%11) did not have sufficientRegarding the relation between the degree of knowledge and thrapeutic therapy which was the main objective in this research,the result ofperson,s correlation coefficient (z= 7.88, r-o.62 jshowed a direct correlation in such a manner that the degree of knowledge will increase with quality of therapeutic regimen.

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Background & Objective: The chronic diseases such as cancer could seriously affect health and consequently quality of life of individuals. The purpose of this study is to evaluate the quality of life in the patients who have been recently diagnosed with caner.
Methods & Materials: This research is a descriptive - analytical study aims to determine quality of life in newly diagnosed cancer patients in selected oncology clinics of Tehran University of Medical Sciences. In this research, 196 newly diagnosed cancer patients were selected by simple sampling method and based on aim. The data were collected by a questionnaire including demographic data, disease characteristic and questions about quality of life in physical, physiological and socioeconomic aspects. The socioeconomic questionnaire presented to the patients after his/ her permission and giving necessary descriptions to him/ her about the objectives of the research. The questions were read for illiterate patients by researcher. The SPSS program was used for data analysis. Descriptive statistics such as absolute/ relative and average sufficiency and deductive statistics such as 2 test were used as well.
Results: The research results show that the quality of life in physical aspect is desirable in majority (67/9%) of patients. The quality of life in physiological aspect is desirable in majority (63.3%) of patients and as well the quality of life in socioeconomic aspect is desirable in majority (76.5%) of patients. The research conclusion shows that there is a meaningful relationship between number of children and economic status (P<0.001) and quality of life in physical aspect. There is a meaningful relationship between economic status with quality of life in psychological aspect and with quality of life in socioeconomic aspect (P<0.05). There is a meaningful relationship between type of cancer, disease stage at the time of diagnosis (P<0.001), and quality of life in physical aspect. There is a meaningful relationship between disease stage (P=0.002), and quality of life in psychological aspect and quality of life in socioeconomic aspect (P<0.05).
Conclusion: The research result shows that the quality of life in physical, psychological and socioeconomic aspects is desirable in the society. Thus the nurses can play an important role in increasing the quality of life of such patients.

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Background & Aim: Exercise is an integral component of physical and mental health. Attention to exercise in women, regarding their physiologic situation is essential. This study aimed to investigate the effect of a specific aerobic exercise program on fetal growth in pregnant women.
Methods & Materials: In this clinical trial, 39 pregnant women in 24-32 weeks of gestation were enrolled. The participants were randomly allocated to experimental (n=18) and control (n=21) groups. Women with single pregnancies and intact amniotic membranes were included. Women who had any contraindications for exercise were excluded from the study. Exercise program included stretching and flexibility exercise and aerobic exercise (constant walking for 30-45 minuets) three days a week for eight weeks. Data were analyzed using descriptive statistics, c², t-test, Kolmogro-smirnov and repeated measurements. P<0.05 was considered to be significant.
Results: The results showed a 1.37% increase in the newborns&apos weight in the intervention group however, the difference was not statistically significant. The average of head circumference and newborns&apos length in the intervention group&aposs newborns were 0.21cm and 0.09cm more than the control group&aposs newborns, respectively. These differences were not statistically significant too (P>0.05).
Conclusion: There were no reductions in the growth of the fetuses following the exercise activities. This kind of exercise has no adverse effect on fetal growth.

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  Background & Aim : Childhood cancer discloses family, and mother in particular, to a number of challenges. It consumes a lot of time, energy, and money of parents to fulfill their caring responsibilities. In some cases and along with increase of caring pressure, mental health of parents deteriorates. The vesting consequences of such events may alter the process of children caring and their quality of life (QoL). The purpose of this study was to examine the relationship between mother’s general health status with the QoL of the child diagnosed with cancer.

  Methods & Materials : In this descriptive cross-sectional study, 124 mothers of children diagnosed with cancer and aged 6-14 years old, referred to Imam Reza and Amir Hospitals in Shiraz during a four month period (from early November to late February) were selected to the study. Data were gathered using the following instruments: 1) the questionnaire of factors related to QoL in children 2) mother's general health status form 3) TNO_AZL Children Quality of Life (TACQOL) and 4) Ped QL Cancer Module. Data were collected through interviewing with mothers and reviewing the medical records of the hospitals. Data were analyzed using the Kruskal–Wallis, Spearman correlation coefficient, Mann-whiteny test and logistic regression in the SPSS-19.

  Results: : A few number of mothers (7.3%) reported good general health status and a large number described their general health status as moderate (55.6%) and poor (37.1%). The mean of health related QoL score and the specific QoL score for children were 78.45±10.05 and 65.51±17.54, respectively. According to the multi-factorial logistic regression, demographic and social factors such as child’s age and treatment-related factors including the period of radiotherapy, along with the duration of disease were more correlated with health and specific QoL scores in children, compared to the mothers’ general health status score.

  Conclusion : Results from this study suggested that emotional support is as important as financial empowerment. The QoL in these patients and their families may improve by identifying the families who are at risk of mental problems.

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Background & Aim: Sedation after coronary artery bypass graft surgery can prevent the side effects of the treatment. The purpose of this study was to determine the effect of controlled sedation based on the Richmond scale on the duration of mechanical ventilation and the changes of blood pressure in patients following coronary artery bypass graft surgery.
Methods & Materials: In a single blind randomized clinical trial (IRCT2017050517693N2) from June to August 2017, a convenience sample of 80 patients after coronary artery bypass graft surgery, hospitalized in the intensive care unit of Heshamat Center, Rasht, were selected and randomly allocated into two groups (each group=40). Sedative drug dose was determined using the Richmond agitation sedation scale in the intervention group and determined routinely (based on hemodynamic changes) in the control group. Pain as a confounding variable was evaluated using CPOT tool. Data were analyzed by descriptive statistics and Chi-square, Mann-Whitney, independent t-test and repeated measures ANOVA using the SPSS software version 22.
Results: The mean age of samples was 59.89±7.53 and 66.7% of them were male. There was a significant difference between two groups in the duration of mechanical ventilation (P<0.04), the changes of patients’ blood pressure (P<0.05), need for a vasopressor drug (P<0.05) until extubation and need for the first administration of sedatives (P<0.001).
Conclusion: Utilizing the Richmond tool can reduce the patient’s dependence on ventilator and changes in arterial pressure. Also, using this tool can prevent unnecessary and early administration of sedative and vasopressor drugs in patients.
 
 

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Background & Aim: Anxiety is one of the most common complications in cancer patients that can affect the physical and mental health of patients and disrupt the treatment process. For this reason, cancer patients undergoing chemotherapy need education about the disease and ways to cope with its complications and problems. The aim of this study was to compare the effects of video and written training methods on anxiety in patients with gastric and esophageal cancer undergoing outpatient chemotherapy.
Methods & Materials: This study is a randomized clinical trial that was conducted on 58 patients with gastric and esophageal cancer who underwent outpatient chemotherapy in Shariati and Imam Khomeini hospitals in Tehran. Participants were randomly assigned to either the video training group (n=28) or the written training group (n=30). Data was collected using the Spielberger State Anxiety Inventory (STAI), at the beginning of the study and then weekly for 12 weeks. The SPSS software version 20 was used to analyze the data.
Results: The results showed that the level of anxiety in both groups was significantly lower compared to before the intervention (P<0.05). There was no statistically significant difference in the anxiety mean score between the video group (56.07±9.85) and the written group (56.40±8.13) after the intervention (P=0.89).
Conclusion: In general, the results of this study showed that self-care education using video and written methods reduces the anxiety of cancer patients undergoing chemotherapy and both methods can be effective in reducing patients' anxiety.
Clinical trial registry: IRCT20181115041669N1