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This is a retrospective research in order to compare the side effect of DMPA with OCP in reproductive women referring to health center in Kalaleh in year 1998. In this assessment the total number of women participated were 198, from this 115 were using Depo medroxy progesterone injection, and 83 women taking OCP. All the research subjects were assessed for having specifice character necessary for this research, and participated willingly. Data collecting was done by the means of questionnaire and checklist, data analysis was performed. The result revealed most users of DMPA were older with higher incidence of pregnancy and more children, lower socio - economical education and using injection for shorter period, comparing to women taking tablets, however the users of injection were taking OCP before, but those taking OCP never used any other method of contraceptive. There was a significant differences in headache, nausea, decreased vaginal discharge and menstrual problems, but no significant differences in acne, backache, leg cramps, mastalgia and hair loss were observed.

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Background & Aim: Although chemotherapy is effective in treating leukemia, it is associated with multiple adverse effects. Mothers, as key members of the healthcare team, need adequate information regarding these side effects to provide optimal care. This study aimed to investigate the side effects of chemotherapy in pediatric and adolescent leukemia patients and examine their relationship with maternal treatment knowledge.
Methods & Materials: This descriptive, cross-sectional study was conducted in 2023 and involved 110 mothers and their children aged 6-18 years hospitalized for leukemia at educational hospitals in Tabriz. A convenience sampling method was employed. Data collection instruments included the American Cancer Society's chemotherapy side effects checklist and an information questionnaire for parents of children with cancer, developed by Motlagh et al. The data were analyzed using SPSS version 24, applying chi-square tests, one-way ANOVA, paired t-tests, Pearson correlation coefficients, and repeated measures ANOVA.
Results: The mean age of mothers was 37 years, and that of the children was 11.61 years. The majority of diagnoses were Acute Lymphoblastic Leukemia (ALL). The severity of complications—such as fever, nausea, vomiting, mouth mucositis, diarrhea, anorexia, and bleeding—showed a significant increasing trend over the four-week observation period (P<0.001). Additionally, a significant difference was observed in mothers' treatment knowledge between the first and fourth weeks (P<0.001). There was a significant relationship between chemotherapy complications and mothers' treatment knowledge (P<0.05).
Conclusion: Mothers actively seek and obtain information regarding their children’s chemotherapy treatment, with their knowledge increasing as complication severity rises. Awareness of side effects and their management strategies enables parents to provide appropriate care and empowers caregivers to offer the best advice and support to patients and their families throughout the treatment course.

 

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Background & Aim: Patients with hyperthyroidism need targeted interventions aimed at improving their quality of life and increasing awareness of potential drug side effects. This study aimed to investigate the effect of an intervention based on the continuous care model on drug side effects and quality of life in patients with hyperthyroidism.
Methods & Materials: This quasi-experimental study was conducted in 2021 on 75 hyperthyroid patients attending the endocrine clinics of Imam Khomeini Hospital and Shariati Hospital in Tehran. Participants were allocated into two groups of 38 patients each, using block randomization. The intervention group received care based on the continuous care model, while the control group received routine care. Data collection employed questionnaires assessing drug side effects and quality of life, administered before and after the intervention. Data were analyzed using SPSS version 25, employing both descriptive and inferential statistical methods.
Results: Analysis of covariance showed significant differences between the groups in both quality of life and drug side effects scores (P<0.001). Post-intervention, the mean quality of life scores across all dimensions were significantly higher in the intervention group compared to the control (P<0.001). Conversely, the mean scores for drug side effects and their respective dimensions were significantly lower in the intervention group following the intervention (P<0.001).
Conclusion: The findings suggest that implementing a continuous care model over a three-month period can positively influence the quality of life and decrease drug side effects among patients with hyperthyroidism.