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Background & Aim: Considering the importance and high prevalence of hepatitis C among substance abusers, especially injection drug users, this study aimed to determine the prevalence and risk factors of Hepatitis C in self-introduced substance abusers in Farabi Addiction Hospital in Kermanshah in 2007.

Methods & Materials: A total of 263 drug addicts&apos medical files were assessed during the study. Data (individual characteristics and results of serological tests) were gathered through the files. Data were analyzed by measuring frequency of correlation between the variables (Chi square test and logistic regression).

Results: The mean age was 31.82±9.18 years mean duration of drug abuse was 121.7±29.1 months for prisoners. From 263 individuals in the study, 22.1% were infected with HCV. The most common ways of substance use were injection (33.1%), and fumigation (32.3%). There was no history of imprisonment in 74.9% of individuals and 52.9% had no history of drug injection. There was a history of physical or mental disorder in 25.5% of individuals. The Chi square statistical test showed significant relationship between HCV infection and substance abuse, and the way of consumption and the t-test showed significant relationship with average daily consumption frequency. The highest relative risk ratio was for positive history of physical or mental illness (OR=8.33), and positive history of imprisonment (OR=5.94). Having multiple sexual partners increased the risk of being infected with the HCV (OR=2.92).

Conclusion: The risk of HCV infection was independently increased with having a history of imprisonment, having multiple sexual partners, presence of physical or mental illnesses, and consumption methods in substance abusers.

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Background & Aim: Addiction as a crisis and a chronic long-term disorder can lead to mental health symptoms in the users and their family members, the most common of which are stress, anxiety and depression. The aim of the study was to determine the effect of a quality of life intervention on the psychological reactions in family caregivers of addicts.
Methods & Materials: This study is a clinical trial. The research population included the family caregivers of addicts admitted to Baharan psychiatric hospital in 2018. The sample consisted of 80 subjects who were randomly divided into intervention and control groups. The caregivers in the intervention group received eight sessions of group counseling based on quality of life therapy and based on specified content, every other day. Eight weeks after the intervention, the data were collected using the DASS-21, and were analyzed by the SPSS software version 21 using paired t test, independent t test, Chi-square and Covariance.
Results: After the quality of life intervention, the mean scores of stress, anxiety and depression in family caregivers in the intervention group (11.50±4.36, 11.05±3.49, 10.57±4.67) were significantly lower than those of in the control group (14.67±4.93, 14.02±4.33, 13.40±4.77) (P<0.01). There were no significant differences in these variables between the two groups before the intervention.
Conclusion: Counseling based on quality of life therapy in this study had a positive and significant effect on reducing the severity of psychological reactions in family caregivers of addicts. Therefore, health care providers are recommended to use this counseling approach along with addiction treatment programs to increase the welfare and psychological well-being of family caregivers.
Clinical trial registry: IRCT20160924029954N11