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This study was a randomized double - blind controlled clinical trial to investigate the effect of nitroglycerine ointment on primary dysmenorrhea and its side effects among the students resident of selected dormitory of Tehran university of medical sciences in 1999.The investigated units consisted of 112 students suffering from primary dysmenorrhea grade 2 and 3.The samples were randomly assigned into two equal groups : control Group (56 students )and experimental group (56 students )as well.The severity of pain and side effects were evaluated once before and five times after applying the ointment. Then ,a comparison was made to assess the effect of drug and placebo on two groups according to severity of pain and side effects.The results showed that severity of pain in case group was significantly lower than control group during 30 minutes and one, two and four hours after applying the ointment, (in all cases p=o.oo)Moreover , 15 -30 minutes after applying the ointment, it was effective in relieving pain and it reached its highest degree when two hours passed, then the effectiveness of the ointment in relieving pain was reduced , but it continued to be effective within four hours after applying as well. Furthermore, the findings revealed that 5 mg of Nitroglycerine 1% was effective in relieving primary dysmenorrhea, however, it was accompanied with following side effects in two groups: headache 21.4% in case group VS 1.8% in control group (p=0.00), dizziness 21.4%in case group VS 1.8% in control group (p=0.00), hotflashing 35.7% in case group vs 1.8% in control group (p=0.00), arrhythmia 10.8% in case group VS 0% in control group (p= C.05), a significant falling in systolic and diastolic blood pressure (p=0.05) and a significant increasing in heart beat. (p=0.05).

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Background & Aim: Primary dysmenorrhea is highly prevalanet and causes much work loss and discomfort. Regard to critical role of women in family and society it is necessitate that to betaken proper investment for improving their mental and physical health.

Methods & Materials: In this study 100 student suffer from primary dysmenorrhea were selected by targeted sampling and take their in two equal groups, case (acupressure group) and control (sham group) randomly. Initially in addition to personal identity, we recorded their history of menstruation, physical activity, vital signs, menstrual pain intensity. Treatment was given during two consecutive menstrual cycles coincident with pain and bleeding by acupressure in case group, and pressure in control group in two time of 15 minutes and 30 minutes interval during 6 hours after onset of dysmenorrhea in each cycle. In case group the treatment was given on lumbar, abdomine, foreleg and ear points, and in control group on placebo points by single blind method. Pain rating was done with use of V.A.S (Visual Analgesic Scale) in 30 min, 1 hr, 2hr and 3hr interval after treatment.

Results: The results showed that mean pain scores before (8.21.6) and after (2.61.3) in case group have significant difference. Also there is significant difference between mean pain score before and after treatment in case and control groups (p<0.001).

Conclusion: This study showed that acupressure at specific points in lumbar, abdominal, ear reduce the pan intensity and psychic and mental due to primary dymenorrhea. Therefore acupressure could be used as a non-medicament, inexpensive and safe method in decrease of pain of dysmenorrhea in girl and women.

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Background & Aim: Dysmenorrhea is a common problem in young women. Although dysmenorrhea is not life threatening, it can have adverse effects on quality of life. Various treatments are offered for dysmenorrhea including vitamin E supplements. This study investigated the effect of vitamin E on primary dysmenorrhea.

Methods & Materials: In this before-after clinical trial, 200 female students who suffered from primary dysmenorrhea were recruited to the study at Mashhad University of Medical Sciences. First, they filled a questionnaire including demographic characteristics and the pain measurement chart (duration and severity). Then, they were divided into three groups: low, moderate and severe dysmenorrhea groups. Vitamin E (200 mg) tablets were administered to them and they were requested to have them once/day for five days (two days before and three days after the beginning of the menstruation). They filled the pain measurement chart (duration and severity) after two treatment periods. Data were analyzed using t-student, chi-square, and variance analysis tests in SPSS software.

Results: The age of the students ranged 19-26 years old. The severity of dysmenorrhea was mild, moderate, and severe respectively in 28%, 60%, and 14% of the students. The mean of painful menstrual days was 2.05 in the first month, and 2.08 in the second month before using vitamin E. After using vitamin E, painful menstrual days were 1.63 in the first month and 1.64 in the second month. Regarding duration of painful days, all of the participants felt pain in the first day of menstruation. After using vitamin E, about one sixth of the participants in the first month and one fifth of them in the second month had no pain at first day. The severity of pain was 5.18 before using vitamin E that decreased to 3.40 after the intervention.

Conclusion: Vitamin E administration in women, who suffer from primary dysmenorrhea, significantly reduces the severity and duration of pain. It can be used as an alternative treatment method in affected women.

 

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Background & Aim: Primary dysmenorrhea is a common medical disorder in young women that affects their quality of life. According to the research studies, overweight and obesity increase biosynthesis of the prostaglandin and consequently increase the severity of dysmenorrhea. The aim of this study was to examine the prevalence and severity of primary dismenorrhea and its relation to anthropometric parameters.

Methods & Materials: In this descriptive-analytical study, 388 students from Ahwaz University of Medical Sciences were selected using random cluster sampling. Demographic data were collected using a questionnaire. The height and weight, BMI, fat mass, waist and hip circumferences, waist to hip ratio (WHR) and waist to height ratio (WHtR) were measured. Visual Analogue Scale (VAS) was used to evaluate the severity of dysmenorrhea. Data were analyzed using Pearson correlation test. The p<0.05 was considered to be significant.

Results: Mean age of the participants was 20.7±1.8 years. The mean age at menarche was 13.4±1.2 years. Moderate or severe dysmenorrheal were experienced by 71.65% of the participants. The severity of dysmenorrhea was significantly related to body fat mass, waist circumference, hip circumference and WHtR (P<0.05). However, there was no significant relationship between the severity of dysmenorrhea with weight or BMI.

Conclusion: Anthropometric parameters that are associated with central obesity such as waist circumference and WHtR are more related to the severity of dysmenorrhea. Increased visceral fat mass is a more effective predictor for dysmenorrhea. More studies are needed to clarify these relationships.