Introduction: A variety of maladies, sometimes disabling, beset many ovulatory women in a recurrent manner during the luteal phase of each ovarian cycle. These problems can deteriorate interpersonal relationships and/or interfere with normal activities of life. Present research was performed to evaluate effects of hypericum perforatum for treatment of physical symptoms of premenstrual syndrome.

Materials and Methods: This study was a randomized, double-blind, placebo-controlled, parallel group compassion study performed over two menstrual cycles on student of Tehran University of Medical Sciences and Tehran University. Volunteers underwent a preliminary screening interview, completed Beck questionnaire as a screening test for depression and attended a medical screening visit before being diagnosed as having premenstrual syndrome. Participants administrated hypericum or placebo, 30 drops BD, for two complete cycles. Premenstrual symptoms were evaluated by a daily symptom report form. Data analysis performed by Chi square, Fisher exact, Wilcoxon and t tests.

Results: Premenstrual daily hypericum caused a significant improvement in mean daily score of severity of premenstrual problems compared to placebo (p<0.05). Premenstrual administration of hypericum, 30 drop BD, showed significant advantage over placebo for physical disorders (%49, p=000).

Conclusion: Daily premenstrual administration of hypericum perforatum treats physical symptoms of premenstrual syndrome. It seems that hypericum perforatum can improve symptoms of premenstrual syndrome.

Background & Aim: Regarding to increasing of life expectancy, Women spend a greater proportion of their life in menopause that is associated with complications and makes disability for them. One of the safe treatments for these complications is herbal therapy.

Methods & Materials: This research is a semiexperimental study. Randomized cluster sampling method was used to select 50 menopaused women ranging from 45 to 55 years old. Experimental group used vitagnus (40 drops daily) for three months. The data was collected by interviewing and a structured questionnaire and daily diary. The data was analyzed by descriptive (percent, mean, standard deviation) and inferencing (2, t-test, Mcnimar, repeated ANOVA) statistical methods by SPSS software.

Results: The results showed a significant reduction in early menopausal complications after intervention (p<0.05). The most major improvement in menopaused women was realated to hotflash (52.2%) and night sweat (51.3%). The other complications showed moderate improvement. Conclusion: Vitagnus is effective in improving of early menopausal complications and therefore doctors and midwives can prescribe vitex instead of HRT in menopausal women.