Abstract: (8528 Views)
In this article, we review animal models of types 1 and 2 diabetes mellitus. Models of type 1 diabetes are discussed in two parts, genetic and chemical. Models of type 2 diabetes are discussed in four parts – rat and mouse models, dietary induction, and selective breeding. Models are assessed regarding metabolic disturbances, the condition of the pancreas, long-term complications, and research benefits.
Type of Study:
Review |
Subject:
General Received: 2013/08/20 | Accepted: 2013/09/10 | Published: 2013/09/10