Volume 18, Issue 5 (7-2019)
ijdld 2019, 18(5): 275-281 |
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Tabibirad S, Abednatanzi H, Nikbakht H, Ghazalian F, Gholami M. EFFECTS OF AEROBIC TRAINING ON DIPEPTIDYL PEPTIDASE-4 AND GLUCAGON-LIKE PEPTIDE-1 IN OBESE WOMEN WITH TYPE 2 DIABETES. ijdld 2019; 18 (5) :275-281
URL: http://ijdld.tums.ac.ir/article-1-5851-en.html
URL: http://ijdld.tums.ac.ir/article-1-5851-en.html
Saeideh Tabibirad1 
, Hosein Abednatanzi * 2, Hojatallah Nikbakht1 , Farshad Ghazalian1 , Mandana Gholami1
, Hosein Abednatanzi * 2, Hojatallah Nikbakht1 , Farshad Ghazalian1 , Mandana Gholami1
1- Department of Sport Physiology, Islamic Azad University, Science and Research Branch, Tehran
2- Department of Sport Physiology, Islamic Azad University, Science and Research Branch, Tehran ,Abednazari@gmail.com
2- Department of Sport Physiology, Islamic Azad University, Science and Research Branch, Tehran ,
Abstract: (3164 Views)
Background: Obesity increases the risk of developing type 2 diabetes with regard to the hormones involved. The purpose of this quasi-experimental study was to investigate the effect of aerobic exercise on Dpp-4 and GLP-1 in obese women with type 2 diabetes.
Methods: From among obese women with type-2 diabetes mellitus 35-50 years old referred to the Diabetes Association of Saveh, 20 people were voluntarily selected and randomly assigned to two groups of control (10) and Experiment group (10) were divided. Twenty four hours before the beginning of the training, the individual characteristics of the subjects included age, height, weight, body mass index and research variables (insulin resistance, Dpp-4 and GLP-1) in the pre-test and the training group Aerobic exercise lasted for 8 weeks, 3 sessions per week, and 45-60 minutes each session, and the control group did not practice. After 8 weeks and 24 hours after the last training session, the individual characteristics and variables of the research were again measured. Data were analyzed by independent t-test and dependent t-test at p≤0.05.
Results: There was a significant increase in the level of GLP-1 (P= 0.001) and a significant decrease in DPP-4 level (P= 0.001) in the aerobic exercise group compared to the control group.
Conclusion: Results showed that Dpp-4 and GLP-1 values were significantly different in aerobic training group after 8 weeks compared to control group. It was also found that aerobic training significantly increased the level of GLP-1 and decreased the level of DPP-4.
Methods: From among obese women with type-2 diabetes mellitus 35-50 years old referred to the Diabetes Association of Saveh, 20 people were voluntarily selected and randomly assigned to two groups of control (10) and Experiment group (10) were divided. Twenty four hours before the beginning of the training, the individual characteristics of the subjects included age, height, weight, body mass index and research variables (insulin resistance, Dpp-4 and GLP-1) in the pre-test and the training group Aerobic exercise lasted for 8 weeks, 3 sessions per week, and 45-60 minutes each session, and the control group did not practice. After 8 weeks and 24 hours after the last training session, the individual characteristics and variables of the research were again measured. Data were analyzed by independent t-test and dependent t-test at p≤0.05.
Results: There was a significant increase in the level of GLP-1 (P= 0.001) and a significant decrease in DPP-4 level (P= 0.001) in the aerobic exercise group compared to the control group.
Conclusion: Results showed that Dpp-4 and GLP-1 values were significantly different in aerobic training group after 8 weeks compared to control group. It was also found that aerobic training significantly increased the level of GLP-1 and decreased the level of DPP-4.
Type of Study: Applicable |
Subject:
General
Received: 2019/05/11 | Accepted: 2019/10/7 | Published: 2019/07/1
Received: 2019/05/11 | Accepted: 2019/10/7 | Published: 2019/07/1
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