1- PhD Student in Physical Education, Mahallat Branch, Islamic Azad University, Mahallat, Iran.
2- Arak Branch, Islamic Azad University
3- Arak Branch, Islamic Azad University ,Mo.malekipooya@iau.ac.ir
4- Bahram Abedi: Professor, Department of Exercise Physiology, Tehran north Branch, Islamic Azad University, Tehran, Iran
2- Arak Branch, Islamic Azad University
3- Arak Branch, Islamic Azad University ,
4- Bahram Abedi: Professor, Department of Exercise Physiology, Tehran north Branch, Islamic Azad University, Tehran, Iran
Abstract: (82 Views)
Background: Obesity is a disease whose incidence and burden on societies around the world is increasing. Sexual performance in these patients is an important aspect that is often ignored. Therefore, the aim of the present study was to investigate the effect of a period of exercise along with electrical stimulation on the gene expression of some sex markers in testicular tissue of fasted obese rats.
Methods: In this experimental study, with a control group of 40 male rats after induction of obesity and weight gain, randomly divided into 5 groups: control, fasting-obese, fasting-endurance exercise, fasting-electrical stimulation and Fasting-endurance training-electrical stimulation were divided. Intervention groups for a period of 4 weeks under endurance sports activity (with a speed of 10 to 20 m/min and duration of 20 to 40 minutes), electrical stimulation (foot shock device for 0.5 mA and 20 minutes) and fasting were placed. After exercise and anesthesia, brain tissue was done and after molecular processes, gene expression was measured using Real time-PCR machine.
Results: The results showed that training led to a significant increase in the expression of 5-alpha reductase and aromatase genes in samples compared to the fasted obese group (P=0.0001). Also, electrical stimulation and its combination with endurance training showed a significant increase in the 5-alpha reductase gene (P=0.0001).
Conclusion: It seems that endurance training and combined electrical stimulation of both during fasting by increasing the expression of 5-alpha reductase and aromatase genes in obese samples are effective in their sexual health and lead to its improvement.
Methods: In this experimental study, with a control group of 40 male rats after induction of obesity and weight gain, randomly divided into 5 groups: control, fasting-obese, fasting-endurance exercise, fasting-electrical stimulation and Fasting-endurance training-electrical stimulation were divided. Intervention groups for a period of 4 weeks under endurance sports activity (with a speed of 10 to 20 m/min and duration of 20 to 40 minutes), electrical stimulation (foot shock device for 0.5 mA and 20 minutes) and fasting were placed. After exercise and anesthesia, brain tissue was done and after molecular processes, gene expression was measured using Real time-PCR machine.
Results: The results showed that training led to a significant increase in the expression of 5-alpha reductase and aromatase genes in samples compared to the fasted obese group (P=0.0001). Also, electrical stimulation and its combination with endurance training showed a significant increase in the 5-alpha reductase gene (P=0.0001).
Conclusion: It seems that endurance training and combined electrical stimulation of both during fasting by increasing the expression of 5-alpha reductase and aromatase genes in obese samples are effective in their sexual health and lead to its improvement.
Keywords: Obesity, fasting, endurance exercise, electrical stimulation, 5-alpha reductase, aromatase
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