Showing 9 results for Akbari
Bagher Larijani, Seyed Sajad Mohseni Salehi, Shirin Irani, Marjan Akbari Kamrani, Nasim Sheykh Bahaei, Ahmad Sajadi, Seyed Naser Ostad,
Volume 6, Issue 1 (19 2006)
Abstract
Background: Many researches have been conducted on islet cells' transplantation for a definitive treatment of diabetes mellitus type1. As the viability of the islets is the most important factor in predicting the transplantation prognosis, we have designed a study to isolate rat's islets. The aim of the study was to assess the viability of the islets at different stages and suggest the best transplantation time.
Methods: Pancreatic islets were isolated from male rats (250-300gr) by standard surgical procurement followed by intraductal HBSS distension, chopping and digestion with collagenase (type V). After being centrifuged for 3 times, the islets were then hand-picked and incubated in 37oC with RPMI 1640 media for 6 days. Each well contained 35-45 islets. Viability of islets was assessed by 2 independent investigators, giving score 0-2 to the color of islets under florescent microscope after Propidium iodide/Acridine orange staining at 6 times: just after the incubation, 24h, 48h, 3rd day, 5th and 6th day.
Results: The viability of the islet cells was gradually increased after the incubation as we had the most viability rate after the second day, while it decreased after this period and reached the least rate on the 5th and 6th day.
Conclusion: The islets' viability increased following the cell culture after the isolation procedure, as they have the best condition for transplantation after 48 hours. As the islets’ viability is the most critical point in transplantation, further studies evaluating the effects of different interventions on viability is needed.
Malihe Akbari Abdolabadi, Bahram Mohebbi, Roya Sadeghi, Azar Tol, Mahmood Mahmoudi Majdabadi,
Volume 16, Issue 1 (1-2017)
Abstract
Background: Overcoming barriers associated with diabetes is considered a logical infrastructure to empower diabetic patients in management of living with diabetes and identify factors which affect these barriers. This study aimed to determine the effect of an educational intervention based on the BASNEF model on barriers to awareness, lifestyle, adaptation, and support in living with diabetes in patients with type 2 diabetes and it's related factors.
Methods: This was a quasi-experimental study which. Performed among 168 patients with type 2 diabetes referred to health centers of Beheshti University of Medical Sciences from August to September 2014. Before the educational intervention, questionnaires of life barriers and the BASNEF structures were completed. After pre-test, the patients were randomly allocated to the case and control groups based on randomizing four block design. Only in the intervention group patients received six education sessions of 45 to 60 minutes that fifth education session with their families, and related staff. The educational program was designed based on the BASNEF constructs (Knowledge, attitude, subjective norm, enabling factors and behavioral intention), and educational content was developed based on the barriers to living with diabetes (awareness, lifestyle, adaptation, and protection). Data analyzed Spss stafware version 20 utelized to data analysis using statistical tests such as independent sample t-test, paired t test, Wilcoxon, McNemar test, and Mann-Whitney U
Results: Our findings showed that there was a significant difference between a score received on components of barriers to of living with diabetes (awareness, lifestyle, adaptation, and protection) and variable of the BASNEF model (knowledge, attitude, subjective norm, enabling factors and behavioral intention) before and after the educational intervention the significant level was set less than 0.05 (P<0.05).
Conclusion: Education in type 2 diabetic patients based on BASNEF, as a model for effective education, can lead to dimensions barriers reduction in (awareness, lifestyle, adaptation, and protection).
Azar Tol, Bahram Mohebbi, Roya Sadeghi, Mehdi Yaseri, Malihe Akbari Abdolabadi, Fateme Dadrast, Parvin Abassi Borojeni,
Volume 16, Issue 1 (1-2017)
Abstract
Background: Improving self-care behaviors happened by self-efficacy which result in better quality of life. Current study aimed at assessing the perceived coping self-efficacy predictors among patients with type 2 diabetes referees to health centers affiliated to Tehran University of Medical Sciences.
Methods: In this cross sectional study which was descriptive and analytical one, perceived coping self-efficacy and its effective factors assessed among 536 type 2 diabetic patients referee to Tehran University of medical Sciences using random sampling based on 11-likert scale questionnaire. This questionnaire included 11 items in demographic variables and 24 items in perceived coping self-efficacy. Collected data analyzed by SPSS version 23 using MANCOVA.
Results: Study findings revealed that age (P=0.013), level of education (P<0.036), and HbA1c (P=0.004) had significant relation with total score of perceived coping self-efficacy. But, variables such as gender, occupation, disease duration, marital status, family history and history of chronic disease had no relation with scales of perceived coping self-efficacy.
Conclusion: Planning theory based intervention programs to improve coping self-efficacy among diabetic patients in low socioeconomic status population and poor diabetes control is recommended.
Roohangiz Alirezaei Shahraki, Ahmad Aliakbari Kamrani, Robab Sahaf, Yahola Abolfathi Momtaz, Narjes Khosravi Samani,
Volume 17, Issue 5 (7-2018)
Abstract
Background: Diabetes is a chronic disease that is increasing in the world that has a different outbreak in different societies. 90% to 95% of all types of diabetes include type 2 diabetes. This disease is spreading due to the Industrial life and urbanization .The Nationwide Program for Prevention and Control of Diabetes is already under way for controlling the disease and its side-effects. This study is intended to probe into the effects of the program in the country.
Methods: This study used a cross-sectional pre- and post-test design involving 100 elderly patients newly introduced to be suffering from diabetes who were selected by convenience sampling in Isfahan. The data collection methods were a questionnaire on demography and health, and another one on patients’ levels of fasting blood sugar (FBS) and hemoglobin glycosides (HbA1c(The data was gathered before and three months after the patients’ entrance into the program.
Results: The mean and standard deviation of the fasting blood sugar before the program were 172.73 and 71.68 and after the program 143.02 and 51.19, respectively (P<.001; t=5.30). And finally, glycated hemoglobin mean and standard deviation before the program were 8.24 and 1.9 and after the program 7.44 and 1.66, respectively (P<.001; t=4.79).
Conclusion: The results indicate the importance of the program for the prevention and control of the elderly patients’ diabetes by controlling their fasting blood sugar and glycated hemoglobin.It is recommended that this program be implemented in all health centers of the country.
Masoumeh Akbari, Emad Ashrafi, Asadollah Rajab,
Volume 18, Issue 4 (4-2019)
Abstract
Background: Type 1 diabetes is a chronic disease that children and adolescents do not have the ability to care for themselves, despite having enough information about their self-care (nutrition, insulin, exercise, etc.). Self-care, such as any behavior, can be influenced by the way of thinking, and the philosophy teaching method can be a suitable educational tool for changing thinking. The purpose of this study was to determine the effectiveness of teaching cognitive errors by philosophy for children on increasing the Well-being and reducing the cognitive errors and the level of glucose in children and adolescents with type 1 diabetes.
Methods: The research method was quasi-experiment with pre-test post-test control group (waiting list) design. The sample included 22 children and adolescents of the Iranian Diabetes Association who responded to the cognitive errors scale of children and adolescents Quinn et al., Well-being Questionnaire (WHO-5) and blood glucose (A1C). To test the hypotheses, MANCOVA was used.
Results: The result of MANCOVA was significant. Subsequently, there were significant differences between cognitive errors (F (17,1) =9/01, P=0/008) and Well-being (F (17,1) =7/4, P=0/01) between two groups, but the level of blood glucose (F= (17,1) =0/01, P=0/8) was not significant.
Conclusion: Learning cognitive errors in the philosophy for children and adolescents leads to the growth of reasoning, the rational thinking of children and adolescents, and helps them to take care of themselves in conditions of failure, stress and anxiety, and improves their emotional well-being. However, it seems that it takes longer to effect on blood glucose.
Amir Akbari, Hamid Mohebbi, Elma Tabari,
Volume 19, Issue 2 (1-2020)
Abstract
Background: The aim of this study was to investigate the effects of high fat diet-induced obesity and interval and continuous exercise training on visceral fat SIRT1 and insulin resistance in male rats.
Method: Forty male rats were divided into two groups: high-fat diet (HFD; n=32) and standard diet (C; n=8). After 10 weeks inducing obesity, eight rats from the HFD and C groups were sacrificed, and rest of obese rats were randomly divided into three groups: obesity control (OC), moderate intensity continuous training (MICT) and high intensity interval training (HIIT). The HIIT and MICT protocols were performed for 12 weeks and 5 sessions per week. Visceral fat samples were collected to measure protein levels of SIRT1 by western.
Results: Induction of obesity was associated with a significant decrease in visceral fat SIRT1 and an increase in insulin resistance (P˂0.05). In contrast, both HIIT and MICT significantly increased visceral fat SIRT1 protein levels (P˂0.05), whereas HIIT effects were significantly higher (P˂0.05). Also, both HIIT and MICT protocols improved insulin resistance (P˂0.05).
Conclusion: Exercise training is likely to play an important role in regulation of visceral fat SIRT1 and because of that may be effective in improving insulin resistance. The increase in SIRT1 also appears to be dependent on the intensity of exercise training.
Reza Masoodi, Soleiman Kheiri, Fateme Ali Akbari, Ahmad Ali Eslami, Leili Rabiei,
Volume 19, Issue 6 (8-2020)
Abstract
Background: Assessing the health literacy of diabetic patients requires the availability of a tool specific to this group. The Diabetes Health Literacy Assessment Questionnaire (LAD) is one of the tools used to measure the health literacy of diabetic patients. The present study was conducted with the aim of translating and validating the Persian version of the LAD questionnaire.
Methods: The present study aimed to determine the validity and reliability of the Persian version of the Health Literacy Assessment Questionnaire for diabetic patients on 300 patients with diabetes in 1398, by sampling. Stages of study: First: Translation and preparation of the Persian version of the health literacy questionnaire in order to design and select items and their qualitative evaluation by the second group: Quantitative evaluation of narrative features using the opinions of the third group of experts: Formal narrative evaluation (comprehensibility) and The reliability of the questionnaire was assessed by a small group of the target population in a fourth experimental study: analysis of items, validity assessment and reliability of the final questionnaire.
Results: In the analysis of organizational structure items, the effects of roof and floor were not observed. The highest averages were for items 8 and 12 and the lowest averages were for items 6. According to the Skewness Index, no deviation was observed in the items. Based on the results, the instrument had acceptable internal stability. Detective factor analysis identified two factors for the Diabetes Health Literacy Questionnaire: one was individual understanding and the second was social support.
Conclusion: The results of exploratory factor analysis, Diabetes Health Literacy Questionnaire (LAD) have good validity and reliability and can be used to measure the health literacy of diabetic patients.
Mahnaz Aliakbari Dehkordi, Fatemeh Eisazadeh, Alireza Monzavi Chaleshtari,
Volume 21, Issue 2 (7-2021)
Abstract
Background: Coronary heart disease is a viral infection that has become a pandemic disease. Given the comprehensive impact that this disease has on the lifestyle of individuals, the economic situation of the country, imported drugs; the present study aims to investigate the self-care status of patients with type 2 diabetes during the Covid epidemic.
Methods: The study population in the present study was people with diabetes in Bushehr. The sampling method in the present study was purposeful and available sampling and the sample size was 13 people (7 men and 6 women). The research information was collected through a semi-structured interview for 40 to 60 minutes using open-ended questions. After the interview process, the answers were interpreted and coded using the content analysis method.
Results: According to the results of the present study, in general, patients with type 2 diabetes during the period of Covid-19 epidemic did not have a favorable self-care status and many problems in the field of self-care behavior (medication, nutrition and exercise and mobility) and in other Fields have experienced.
Conclusion: Diabetics have experienced many problems during the Quaid 19 epidemic, which further reduces their quality of life; therefore, the government, the media, the patient's family, the patient himself, doctors, psychologists and counselors can be used to reduce these problems.
Farnaz Onsori, Mina Akbari Rad, Maryam Emadzadeh, Ali Moradi, Mohammad-Javad Mojahedi, Alireza Shariati, Mohammad-Ali Yaghoubi,
Volume 23, Issue 3 (9-2023)
Abstract
Background: Diabetic nephropathy is the main cause of end-stage kidney disease in diabetic patients. Several inflammatory markers related with diabetic nephropathy have been investigated so far. It is necessary to identify easily available and cost-effective indices. We aimed to determine the relationship between the neutrophil to lymphocyte ratio and mean platelet volume with diabetic nephropathy.
Methods: This cross-sectional study was performed from 2021 to 2022 in diabetes clinic of Ghaem hospital, Mashhad. Patients with type II diabetes were categorized into two groups: without and with nephropathy (urinary albumin excretion greater than 30 mg/24h or GFR less than 60). Patients’ data, including demographic data, past medical and drug history and lab data were gathered and analyzed.
Results: In total, 100 diabetic patients including 50 with (mean age=64.04±7.40 years) and 50 without nephropathy (mean age=56.06±6.36 years), were studied. Patients with nephropathy were older, had a longer history of diabetes and a higher blood pressure (P < 0.05). However, the distribution of gender, weight, height, and BMI was not significantly different the two groups (P>0.05). The absolute neutrophil count was not significantly different between the two groups (P>0.05), while the mean platelet volume, neutrophil% and neutrophil/lymphocyte ratio were significantly higher in patients with nephropathy (P<0.05).
Conclusion: According to our findings, patients with diabetic nephropathy had higher mean platelet volume, neutrophil%, and neutrophil/lymphocyte ratios compared to diabetic patients without nephropathy.
