Manouchehr Nakhjavani, Farid Azmoudeh-Ardalan, Arman Mazouji,
Volume 1, Issue 2 (18 2002)
Abstract
Introduction: The urinary excretion of minimal quantities of albumin (microalbuminuria) is predictive of renal failure and cardiovascular mortality. The detection and prompt treatment of microalbuminuria is crucial to the prevention and progress of renal failure in patients with diabetes. The aim of this study is to evaluate the relative frequency of microalbuminuria in different age groups of men and women attending the diabetes clinic at Imam Khomeini University Hospital.
Methods: 123 patients each provided a 12-hour urine sample, collected in standard fashion. Urinary albumin was measured by immunoturbidometry. The frequency of microalbuminuria (urinary albumin excretion between 30mg and 300mg in a 24-hour sample) was assessed in different age groups in men and women, according to duration of diabetes, glomerular filtration rate (GFR), glycosylated haemoglobin levels (A1C), body mass index (BMI), and both systolic and diastolic blood pressure.
Results: Overall, 20.3% of patients had microalbuminuria, 61.1% normoalbuminuria, and 10.6% macroalbuminuria. Patients with microalbuminuria were significantly older (mean age = 58.5 years) than patients with normal albumin excretion (50.3 years). The male-to-female ratio was highest in patients with microalbuminuria and lowest in those with normoalbuminuria. There was no significant difference in GFR, A1C, and blood pressure between patients with normo-, micro-, or microalbuminuria. There was a significant difference in duration of diabetes between normoalbuminuric (9.3 years) and microalbuminuric patients (11.5 years). There was a significant, inverse correlation between BMI and urinary albumin excretion.
Conclusions: Renal function in patients with type 2 diabetes deteriorates with increasing age and duration of diabetes. Renal impairment is more common in men than women.
Mehrab Marzban, Seyed Hesameddim Abbasi, Amir Hosein Lebaschi, Pooya Ghaboosi, Alireza Alaee Alamooti, Ali Ardalan,
Volume 5, Issue 1 (18 2005)
Abstract
Background: Obese patients are usually thought to have an increased risk for complications in coronary artery bypass grafting surgery (CABG). Several studies have been unclear about the relationship between obesity and the risk of adverse outcomes. The aim of this study was to assess the relationship between Body Mass Index (BMI) and in-hospital mortality following CABG.
Methods: Between December 2003 and February 2005, 1258 patients who underwent isolated CABG at Tehran Heart Center were included in this study. Patients were divided into three groups according to their BMI. Patients in group I had BMI<30 (non obese patients). In group II patients had (obese patients). Patients in group III had (very obese patients). Patients in each group were followed for in-hospital death and variables were compared to find any statistically meaningful relationship.
Results: No significant difference was found between non obese and obese patients (group I & II), but hypertension was more prominent in very obese patients (group III) and female sex was more prevalent in this group comparing two other groups. Mortality was more in the 3rd group as well. In non obese diabetic patients, the rate of mortality was higher than other patients. Logistic regression showed that BMI can not be considered as an independent factor to predict the risk of death in post CABG in-hospital mortality.
Conclusion: It seems, in coronary artery bypass grafting, BMI is not an independent factor for predicting in-hospital mortality.
