Showing 2 results for Arjmand
Akram Tayanloo-Beik, Hamidreza Aghayan, Sepideh Alavi-Moghadam, Mostafa Rezaei-Tavirani, Shayesteh Kokabi Hamidpour, Babak Arjmand, Bagher Larijani,
Volume 20, Issue 1 (25th Anniversary of the Foundation, Special Issue 2021)
Abstract
Background: In many years, finding modern and appropriate treatments for diseases, especially chronic diseases (such as chronic metabolic diseases) have been one of the most important issues. On the other hand, limitations related to organ transplantation have made a serious need for advanced therapeutic strategies. In this respect, researchers have recognized the benefits of stem cells as a suitable tool. Accordingly, the application of stem cells for the treatment of various diseases has been considered in many countries around the world especially Iran.
Methods: A review of the history of stem cell studies in Iran and the world was conducted and the Cell Therapy and Reconstructive Medicine Research Center was introduced as one of the leading centers in this field and a review was conducted on the activities of this center.
Results: The history of studies related to cell-based therapy in Iran back to 1990. Subsequently, the Cell Therapy and Reconstructive Medicine Research Center, by providing services based on GMP principles, has provided clinical services in accordance with international standards and has conducted various researches in this field.
Conclusion: The purpose of the current review is to examine the strategies and challenges around the research and treatment opportunities using stem cells in mentioned center.
Shahnaz Esmaeili, Fatemeh Bandarian, Farideh Razi, Hossein Adibi, Ali Jalili, Babak Arjmand, Camelia Rambod, Ensieh Nasli-Esfahani, Bagher Larijani,
Volume 20, Issue 1 (25th Anniversary of the Foundation, Special Issue 2021)
Abstract
Background: Endocrinology and Metabolism Research Institute (EMRI) is one of the largest research institutes in Iran, which has been established to develop research strategies and manage endocrine and metabolic diseases such as diabetes. The purpose of this report is to review and summarize research activities related to diabetes over a quarter of a century at EMRI.
Methods: A comprehensive search of PubMed, Scopus and EMBASE was conducted to find diabetes-related studies in EMRI. After extracting the data, the articles were classified according to the type of article, the level of evidence, the types of diabetes and their subject.
Results: After eliminating duplicates and screening, finally 228 articles were classified. Most diabetes research conducted at the Diabetes Research Center (DRC) was on type 2 diabetes (37%). By article type, most of the articles were original. In addition, clinical studies provided the most evidence in the obtained documents. By topic, most of the articles were related to the basic sciences and factors related to diabetes, followed by studies on the management and prevention of diabetes.
Conclusion: Most of the research conducted in the Diabetes Research Center in the past quarter of a century is of original studies in the field of basic sciences in the field of type 2 diabetes and most of the evidence produced is related to observational studies.
