Showing 3 results for Asadi
Javad Zavar Reza, Mahmoud Dousti, Sadigheh Soleimani, Farzad Asadi Jamnani, Bardia Farzamfar, Shahrnaz Aria Barzin, Ali Jalilian,
Volume 5, Issue 4 (17 2006)
Abstract
Background: Experimental studies have shown that walnut (Juglans regia) intake decreases the risk of coronary heart disease (CHD). Walnut decreases the levels of atherogenic lipids such as TG, LDL-C and VLDL-C. Mainly the effect is induced via 3- Poly Unsaturated Fatty Acids (3-PUFA). Walnuts are a rich source of these fatty acids, especially -Linolenic acid (C18:3 9, 12, 15).
Methods: We assigned 20 hypercholesterolemic male Rats (200-250g) to four groups, and fed with four diet concentration of oil extract Persian walnuts(J. regia)(Lavasanate) (w/w ) as complementary diet: control group (0% oil extract) and cases 5%(1g oil extract/1g weight/1 day) ,7.5%(1.5g oil extract/1g weight/1 day),10%(1g oil extract/1g weight/1 day) for eight weeks.
Results: Results revealed there is a positive effect on the decreasing of TG(14%) ,TC(7.8%) , LDL-C(11%),VLDL-C(12%) serum concentrations, with increasing consumption of oil extract Persian walnuts (5% ,7.5% and 10%).
Conclusion: In view of the positive effect of oil extract Persian walnuts (J. regia) consumption on decrease serum concentration of TG, TC, LDL-C and VLDL-C known as atherogenic lipids and lipoproteins, it may be suggested as a CHD protective dietary supplement.
Baharak Najafi, Seyed Masoud Arzaghi, Hossein Fakhrzadeh, Farshad Sharifi, Shervan Shoaei, Mahtab Alizadeh, Mohsen Asadi Lari, Reza Fadayevatan, Neda Mehrdad,
Volume 13, Issue 1 (1-2014)
Abstract
Introduction: Mental disorders are common in the elderly.The purpose of this study was to assess the
general health status and its related factors among people ≥ 65 years in different districts of Tehran.
Methods: This study has used data of the participants ≥ 65 years old in urban health equity and response
tool (Urban-HEART) study. Finally the data of 1313 elderly were considered for this study. Variables
included demographic characteristics (gender, age, education level, family size, marital status and
employment status) and mental health using the Persian GHQ -28 questionnaire (domains: somatic,
depression, insomnia and anxiety) and quality of life using the SF12.
Results: The mean age of participants was 73.68 (5.91) (women=627 and men=686). GHQ-28 median of
scores the participants were 24.00 (22.00)[20.00 (27.00) in women and 19.00 (19.00) in men
(P<0.01)].Based on GHQ-28 cut-point 23, 50.2%of the participants had mental health problems, [61.2%
women and 40.1% men (P<0.01)].The residents of third municipality districts had the best mental health
(26.3% of men and 38.5% of women had mental health problems) and the aged of 20th municipality
district had the worst health status (65.7% of males and 84.2% of women had mental health problems).In
multivariable logistic regression model, for each year of increment age, 2.9% chance of mental health
problems increased (P<0.01). With increasing level of education, mental health status was improved (P
trend < 0.01). The relationship between family size and mental health was not significant (P =0.06).
Conclusion: Mental health status of the elderly in Tehran was worse than the many other countries. The
elderly lived in 20th
municipal district, had the worst and the dwellers in the 3th
district had the best mental
health status.
Monireh Khalili, Habib Asgharpour, Asra Askari, Jahanbakhsh Asadi,
Volume 23, Issue 6 (1-2024)
Abstract
Background: The health and proper functioning of the endoplasmic reticulum in the liver can lead to an increase in the quality of the metabolism of liver cells. Exercise can lead to liver health by regulating liver enzymes and factors related to apoptosis pathway. Therefore, the aim of the current research is to compare the performance of the endoplasmic reticulum chaperone protein of the liver of healthy model rats with the intervention of different training sessions and starvation.
Methods: In this experimental research, 30 Wistar male rats with a weight range of 330 ± 25 grams were selected and divided into six groups: 1) control, 2) starvation, 3) 3 days of training per week, 4) 5 days of training per week, 5) starvation + 3 training days per week, 6) starvation + 5 training days per week. Training consisted of one hour of continuous running on a treadmill for 4 weeks, and starvation was performed for 14 hours when the rats were awake. Data analysis was performed using one-way analysis of variance and post hoc LSD statistical tests in SPSS version 23 software. A significance level of P≤ 0.05 was considered.
Results: Data analysis showed a significant change in the levels of liver enzymes alanine aminotransferase (ALT) and aspartate transaminase (AST) (P≤ 0.05). This change in CHOP gene expression was also significant (P≤ 0.05).
Conclusion: Aerobic training for 3 and 5 days with starvation can lead to liver health by reducing liver enzymes (AST and ALT) and cell death-related factor (CHOP) through the apoptosis pathway.
