Behzad Foruotan, Sahar Molzemi, Hoosin Harati Por, Shahram Molzemi, Nahide Bolbol Haghighi, Fatemeh Sadat Alam Al-Hoda, Amir Hossein Ashenaii, Seyed Reza Mousavi, Mohammad Reza Jafari, Mohsen Choopani Moghaddam,
Volume 13, Issue 5 (7-2014)
Abstract
Background: Finding effective drugs is considered for healing diabetic wounds by researchers. The purpose of this study is to evaluate the wound healing effects of palmatine in the healing of skin wounds in normal and diabetic rats.
Methods: In this study 16 male Wistar rats were dهvided into four groups (Negative control, Positive control, The first experimental,The second experimental) . A 4 cm2 wound was created in the left side of the spinal cord in each of these groups and the process of wound healing was macroscopically evaluated.
Results: The wounds of the diabetic groups (the diabetes was coused by streptozocin) showed longer healing process in comparison with the normal groups and the wound healing in the experimental groups which were treated by palmitine was faster in comparison with the control group.
Conclusions: the results showed that palmatine speeds the wound healing up in normal and diabetic samples.
