Showing 5 results for Azarbayjani
Babak Hooshmand Moghadam, Mohammad Ali Azarbayjani, Sahabeh Mahdian, Ali Bakhtiyari, Mozhgan Eskandari,
Volume 18, Issue 6 (9-2019)
Abstract
Background: Diabetes and obesity are associated with a decrease in sexual function and sexual activity due to changes in sex hormones. The purpose of this study was to investigate the Independent and interactive effect of Tribulus terrestris supplementation and resistance training on testosterone, FSH, LH and erectile function in obese men with type 2 diabetes.
Methods: In this quasi-experimental study, 40 obese men with type II diabetes (41.97±8.01 years old, BMI 31.97±1.87 kg/m2) were divided into four groups: 1) Resistance training+ placebo 2) Tribulus terrestris 3) Resistance training+Tribulus terrestris 4) Control. Subjects in the first and third groups performed a Resistance training protocol for 8 weeks. Also, the subjects in the second and third groups received Tribulus terrestris 1000 mg daily (two 500 mg capsules) and the first group received the same amount of placebo. Blood samples and questionnaires were collected in two stages before and after the test to assess the biochemical values and erectile function. Statistical analysis of data was performed using t-test, one way ANOVA and Tukey post hoc test at a significance level of 0.05.
Results: Results showed that erectile, testosterone, FSH and LH values increased significantly in the three groups of resistance training, tribulus terrestris and resistance training+tribulus terrestris (P≤0.05). Also, were observed significant difference in all variables between resistance training+tribulus terrestris group whit resistance training and tribulus terrestris groups (P≤0.05).
Conclusion: It seams that eight weeks of independent Tribulus terrestris Consumption and performing Resistance training increases sexual and erectile function. But it seams, combining these two, causes more sexual and erectile dysfunction in obese men with type 2 diabetes.
Hadi Afshar Bakeshlou, Ahmad Abdi, Mohammad Ali Azarbayjani, Alireza Barari,
Volume 19, Issue 2 (1-2020)
Abstract
Background: Diabetes is a chronic and progressive metabolic disorder that leads to more severe cardiac complications. The aim of the present study was to investigate the effects of Berberine chloride at a dose of 50 mg / kg on the heart tissue of streptozotocin-induced diabetic rats with aerobic training.
Methods: 56 male Wistar rats were randomly divided into seven groups (n = 8): control (C), sham (S), Aerobic training control (TC), diabetes mellitus (DM), diabetes-berberine (BDM), diabetes mellitus. Aerobic training (TDM), and aerobic training-berberine (TBDM) were divided. Diabetes was induced by injection of streptozotocin in male rats. The training groups performed aerobic exercise program (10-18 m / min, 10-40 min five days a week) for six weeks on the treadmill for histological evaluation using hematoxylin and eosin (H&E), Masson trichrome and staining Immunohistochemicals were used to measure diameter change, cardiomyocyte rupture, change in nuclei, and collagen deposition in cardiac muscle fibers using one-way ANOVA and Tukey post hoc tests with SPSS 21 software.
Results: The results showed that DM group did not induce cardiomyocyte fibers rupture and collagen deposition and reduction of filament diameter in group C, S and TC and its damage in heart tissue was less in TBDM group than in BDM and TDM groups.
Conclusion: The results showed that berberine supplementation reduced these effects and synergized with aerobic training and reduced the cardiac cardiomyocyte muscle fibers diameter and decreased collagen deposition and better order of nuclei.
Samira Majidi, Abdolali Banaeifar, Mohammad Ali Azarbayjani, Sajad Arshadi,
Volume 21, Issue 6 (3-2022)
Abstract
Background: Diabetes is the most common glandular disease in the world. The aim of this study was to compare the effect of three types of endurance, resistance and combination training on inflammation and insulin resistance in visceral adipose tissue of type 2 diabetic rats.
Methods: For this purpose, among eight-week-old male Wistar rats, 48 rats were selected and randomly divided into 6 groups (diabetic endurance training, diabetic resistance training, diabetic combination training, healthy combined training, healthy control and diabetic control). The rats became diabetic by injecting 95 mg of nicotinamide and after 15 minutes of STZ injection at the rate of 55 mg/kg body weight. 4 days after injection, rats with serum glucose above 300 mg/dL were considered diabetic. Then, the endurance training group trained for 6 weeks, 3 sessions per week with moderate intensity (50-60% of maximum oxygen consumption). The initial load to start resistance training was 50% of the rat's body weight. Each session added 15% of body weight to the weights. The combined exercise group also performed resistance and endurance exercises in a row. 48 hours after the last session, the rats were anesthetized and visceral adipose tissue was removed to examine the variables.
Results: The results showed that there was a significant difference between the effect of six weeks of endurance, resistance and combined exercise on inflammation and insulin resistance in the visceral adipose tissue of male diabetic mice.
Conclusion: The results confirm the effect of three training methods on the mechanisms involved in diabetes.
Sedigheh Babaee, Maghsoud Peere, Mohammad Ali Azarbayjani, Maryam Delfan,
Volume 23, Issue 1 (5-2023)
Abstract
Impaired insulin function with exogenous changes is a major cause of heart failure. The purpose of this study was to investigate the effect of four weeks of high intensity interval training with curcumin supplement on the expression of IRS-1 and IRE-1α gene in the Left ventricle of type 2 diabetic rats.
Methods: In the present experimental study, 30 male mice with diabetes were divided into five groups of 6; high intensity interval training (HIIT), High intensity interval Training+Curcumin(S+HIIT), Diabetic control+curcumin(S+DC), Diabetic Control (DC), Normal control (NC). The High intensity interval training protocol was performed five days a week for four weeks. Curcumin gavage at a dose of 100 mg/kg was performed daily. The expression of IRS-1 and IRE-1α were measured by the qReal-TimePCR method, and data were analyzed by one-way ANOVA at the alpha level of 0.05.
Results: IRS-1 gene expression in the S+HIIT group compared to the DC (P=0.003) and S+DC (P=0.001) groups and in the HIIT group compared to the DC (P=0.002), and S groups +DC had a significant decrease (P=0.019). IRE-1α gene was significantly decreased in S+HIIT group compared to DC (P=0.003), S+DC (P=0.001) and HIIT (P=0.008) groups.
Conclusion: It seems that HIIT with curcumin supplement can reduce the process of myocardial apoptosis in diabetic patients by improving metabolic conditions and genetic factors.
Shahin Riyahi Malayeri, Mohammad Ali Azarbayjani, Nastaran Amini, Azadeh Abdolahzadeh,
Volume 25, Issue 4 (9-2025)
Abstract
Background: Insulin resistance plays a fundamental role in disorders such as obesity, diabetes, cardiovascular diseases, and metabolic syndrome. Regular physical activity and the use of medicinal plants are important strategies for its reduction and management. Ginger has attracted research attention due to its phytochemical compounds that influence insulin signaling pathways. Despite numerous studies, a bibliometric analysis examining the effects of exercise and ginger supplementation on insulin resistance has not yet been conducted. Therefore, the present study aimed to analyze the trends in Iranian research in this field.
Methods: In a bibliometric review, the keywords “training,” “ginger supplementation,” and “insulin resistance” were searched in the Magiran database. According to the entry criteria, 13 eligible articles were selected and data extracted from them, including writing pattern, collaboration, prolific authors and institutions, selected journals and study trends, and common keywords were extracted from the database of recipients and analyzed using VOSviewer software.
Results: The results indicated that 36 authors had an average of 3.23 ± 0.89 cooperation in writing articles. Fifty-four percent of the articles were published by public university faculty and 46% by independent universities. The most frequent keywords included "ginger", "insulin resistance", "obesity", "diabetes mellitus", "irisin" and "lipid peroxidation".
Conclusion: The results of this bibliometric study showed that exercise with ginger supplement reduced insulin resistance. In particular, 84% of the articles showed the positive effect of combined exercises (resistance and aerobic exercises) along with ginger supplements on the reduction of insulin resistance. Compared to other types of exercise, these exercises have had the greatest effect on improving the glycemic profile and body composition. In addition, high intensity interval training (HIIT) has also shown positive effects on reducing insulin resistance, but is not as effective as combined training. Also, due to the relationship between insulin resistance and various diseases, it is felt to conduct more studies on diverse statistical populations and people suffering from various diseases.
