Iranian Journal of

Background: Diabetes is the most common glandular disease in the world. The aim of this study was to compare the effect of three types of endurance, resistance and combination training on inflammation and insulin resistance in visceral adipose tissue of type 2 diabetic rats. 

Methods: For this purpose, among eight-week-old male Wistar rats, 48 ​​rats were selected and randomly divided into 6 groups (diabetic endurance training, diabetic resistance training, diabetic combination training, healthy combined training, healthy control and diabetic control). The rats became diabetic by injecting 95 mg of nicotinamide and after 15 minutes of STZ injection at the rate of 55 mg/kg body weight. 4 days after injection, rats with serum glucose above 300 mg/dL were considered diabetic. Then, the endurance training group trained for 6 weeks, 3 sessions per week with moderate intensity (50-60% of maximum oxygen consumption). The initial load to start resistance training was 50% of the rat's body weight. Each session added 15% of body weight to the weights. The combined exercise group also performed resistance and endurance exercises in a row. 48 hours after the last session, the rats were anesthetized and visceral adipose tissue was removed to examine the variables. 

Results: The results showed that there was a significant difference between the effect of six weeks of endurance, resistance and combined exercise on inflammation and insulin resistance in the visceral adipose tissue of male diabetic mice. 

Conclusion: The results confirm the effect of three training methods on the mechanisms involved in diabetes.

Background: Obesity has been recognized as one of the top 10 health problems by the World Health Organization. The purpose of the present study was to the effect of aerobic training on atrogin, eotaxin and IL-10 indices in obese women. 

Method: The present applied research was a quasi-experimental study in which 30 obese women aged 30-45 years were selected by available method from South Tehran Azad University (2016-2017) and randomly divided into two groups of aerobic exercise and control. 24 hours before the start of training, the individual characteristics of the subjects and the research variables (atrogen, eutoxin and IL-10) were measured in blood tissue, then the subjects of the experimental group had their training program for 8 weeks, 3 They performed one session per week and each session lasted 45-60 minutes under the supervision of a researcher. Dependent and independent t-test was used to analyze the data.

Results: Due to the lack of differences in pre-test scores, it was found that the groups were identical. It was also found that 8 weeks of aerobic exercise had a significant effect on the levels of eutoxin, atrogen and interleukin-10 in obese women (p = 0.001)

Conclusion: According to the research results, it is recommended that obese women exercise aerobically. Use to reduce the negative effects of obesity.