Showing 5 results for Dakani
Mohammad Afkhami Ardakani, Mojgan Modarresi, Elham Amirchaghmaghi,
Volume 3, Issue 1 (16 2004)
Abstract
Diabetes is one of the most common metabolic diseases. The prevalence of diabetes, which is around 4.5 - 6% in Iran, reaches as high as 14.2% in population of age 30 years and over in Yazd. Microalbuminuria is diagnosable before development of nephropathy and could be detected at an early stage when effective therapy can still be carried out. In this stage near normalization of blood glucose, strict blood pressure control and administration of ACE inhibitors can prevent nephropathic complications.
This study was aimed to determine the correlation among microalbuminuria, age, duration of diabetes, body mass Index, serum triglyceride, serum cholesterol and blood pressure in type 2 diabetic inhabitants of Yazd diabetes research center.
Methods: This cross-sectional study was carried out during November 2002-July 2003 to investigate the correlation between microalbuminuria and assumed risk factors. Two hundred and eighty eight type 2 diabetic patients (141 males and 147 females) were selected through consecutive sampling. Results: Overall prevalence of microalbuminuria was 14.2%. Chi-square analysis revealed the association between microalbuminuria and high diastolic blood pressure (P-value=0.003) and duration of diabetes (P-value = 0.001). No statistically significant correlation was found between microalbuminuria and body mass index, serum triglyceride, serum cholesterol and systolic blood pressure.
Conclusion: Determination of urine albumin/creatinin ratio is an easy method for screening microalbuminuria which is recommended for all diabetics especially those with hypertension and a long term history of diabetes.
Mohammad Afkhami Ardakani, Maryam Rashidi,
Volume 6, Issue 1 (19 2006)
Abstract
Background: Pregnancy is a condition that favors oxidative stress mostly because of the mitochondria-rich placenta. Transitional metals, especially Iron, which is particularly abundant in the placenta, are important in the production of free radicals. Also studies showed that free radicals has a role in GDM. This study was performed to compare Iron status between gestational diabetes mellitus (GDM) patients and control groups.
Methods: As a case- control study 34 women with GDM were compared with 34 Healthy women matched for referred center, age, parity and BMI. Iron status measurements including ferritin, serum iron, total iron binding capacity (TIBC), hemoglobin, MCV and MCH at 24-28 weeks of pregnancy were assessed and compared between two groups.
Results: In this study, concentration of serum ferritin, Iron, transferin saturation and hemoglobin, MCV and MCH were significantly higher in GDM group and TIBC was significantly lower in this group as compared with controls (P<0.05). No significant association was observed in other variables including familial history of diabetes and GDM
Conclusion: Our findings indicate an association between increased Iron status and GDM. The role of excess Iron from Iron supplementation in the pathogenesis of GDM needs to be examined.
Mohammad-Reza Rouini, Sima Sadray, Yalda H. Ardakani, Maryam Mokhberi, Sedaghat Solmaz,
Volume 6, Issue 2 (18 2006)
Abstract
Background: Metformin is used in treatment of non-insulin-dependent diabetes mellitus (NIDDM). The present study was aimed to study the pharmacokinetic and pharmaco-dynamic of metformin 500 mg tablet in healthy volunteers.
Methods: The test and reference metformin hydrochloride 500 mg tablets were administered to 12 healthy volunteers in a cross-over study. Metformin serum concentration and decrease in blood sugar levels (dBSL) were used for study of pharmacokinetic and pharmacodynamic.
Results: There was no correlation between phramacodynamic and pharmacokinetic para-meters. Also there was no increase in dBSL-(AUC0-12) with increase metformin serum concentration-time. The results of our study show that both products could be bioequivalent according to serum concentration and not blood sugar data.
Conclusion: There was no concentration – effect (dBSL) correlation for both products. Metformin didn’t decrease the blood glucose in healthy volunteers. In some volunteers there was no increase in blood sugar after meal and dextrose 20% oral solution administration which could be related to decreased absorption of glucose from gastrointestinal tract caused by metformin.
Mina Dakani, Mohammad Fakhri, Ramazan Hasanzadeh,
Volume 21, Issue 3 (9-2021)
Abstract
Background: People with diabetes face psychological challenges. Therefore, it is important to pay attention to cognitive therapies based on mindfulness in this field. The aim of this study was to evaluate the effectiveness of mindfulness-based cognitive therapy on anxiety tolerance and cognitive flexibility in patients with type 2 diabetes.
Methods: The research method was quasi-experimental with pre-test-post-test design with a control group. The statistical population of the present study was all type 2 diabetic patients referred to the Maternal Diabetes Center, Touba Specialized and Sub-Specialized Clinic and Mostafavian Clinic in Sari in 2019-2020. Simple randomization was substituted in experimental (n = 15) and control (n = 15) groups. However, no intervention was performed on the control group during this period. The Simon and Gaher (2005) Emotional Distress Scale and the Doyce and Woodwall (2010) Scale were used to collect data. mean, standard deviation and multivariate analysis of covariance were used to analyze the research data.
Results: The results showed that the effect of Mindfulness-based cognitive therapywas on distress tolerance (F= 28.74, P<0.001) and on Cognitive flexibility (F= 31.57, P<0.001).
Conclusion: Considering the effectiveness of mindfulness-based cognitive therapy on anxiety tolerance and cognitive flexibility, it seems that this treatment can be used to reduce psychological problems in patients with type 2 diabetes.
Batool Yamani Ardakani, Maliehe Mobarakian, Vali Bahrevar, Moradali Zareipour, Sadegh Kazemi, Mojtaba Fattahi Ardakani,
Volume 24, Issue 2 (6-2024)
Abstract
Background: Despite the increased use of complementary medicine by diabetic patients, there is no clear estimation of complementary and herbal medicine use by these patients in Iran. This study was conducted to investigate the uses of herbal medicine among patients with type II diabetes in Yazd, Iran, in 2022.
Methods: A cross-sectional study was carried out on 633 patients with type II diabetes referred to the Diabetes Research Center in Yazd City from June to September 2022. A questionnaire-based theory of planned behavior developed and validated by the researcher was used for data collection. In addition to demographics and disease-related information, the instrument included questions about using herbal medicine used. Descriptive statistics, Chi-square, Fisher's exact, and linear regression tests were used to analyze the data.
Results: The most common herb used was cinnamon (34.7%). The majority of patients used herbs daily (56.9%). Using herbal medicine was significantly associated with Attitude (r= 0.48, p< 0.001) Subjective norm (r= 0.39, p< 0.001), perceived behavior control (r= 0.38, p< 0.001) and intention (r= 0.4, p< 0.001). Constructs of the theory of planned behavior 73% predicted intention to use herbal medicine. Subjective norm structure had the highest predictive power of intention to consume herbal medicine (ß= 0.49, p< 0.001).
Conclusion: Subjective norm is the most predictor of intention to use Herbal medicines in patients with diabetes. Therefore, it is very important to pay attention to the beliefs, customs, and culture of the surrounding community in the correct self-management of disease control and the use of effective drug control.
