Showing 6 results for Heidari
Akbar Soltani, Javad Heidari,
Volume 4, Issue 4 (17 2005)
Abstract
Pyomyositis is a pyogenic infection of the skeletal muscle characterized by muscle pain and swelling. The illness is more commonly seen in the tropics. The diagnosis of pyomyositis is difficult due to its vague clinical presentation and poor localizing signs. The differential diagnosis includes osteomyelitis, septic arthritis, muscle hematoma, muscle rupture and deep vein thrombosis. A delay in diagnosis may result in compartment syndrome, sepsis and death. Pyomyositis can be divided into three clinical stages: Stage 1 is characterized by crampy local muscle pain, swelling, low-grade fever and leukocytosis . The muscle may have a "woody" texture on palpation. Stage 2 is characterized by fever, muscle tenderness, and edema. Aspiration of the affected muscle typically yields pus. Stage 3 is characterized by bacteremia and a toxic appearance. Complications such as septic shock, endocarditis, pneumonia and some others may be present. Definite diagnosis should be made by aspiration or surgical drainage of the abscess. We report a 53 years old patient with diabetes who presented with a swelling and painful buttock and thigh, that was diagnosed with pyomyositis.
Javad Heidari, Seyed Mohammad Akrami, Ramin Heshmat, Parvin Amiri, Hossein Fakhrzadeh, Mohammad Pajouhi,
Volume 5, Issue 3 (17 2006)
Abstract
Background: Uncoupling protein-2 (UCP2), one of the mitochondrial transporter memborane protiens, is suggested as a contributor gene for obesity. A common G/A polymorphism in the UCP2 promoter region is associated with obesity and diabetes.
Methods: As a cross-sectional study, 75 healthy 25-64 years volunteers were randomly selected from Tehran University of Medical Sciences population Lab. DNA was exracted from blood samples then polymorphism and A & G Allel frequencies were determined via PCR and RFLP. The correlation between genotype and such clinical and biochemical parameters as BMI, serum cholesterol and TG was investigated. Results were compared with other similar surveys.
Results: The frequencies of the UCP2 -866G/A genotypes in 75 Iranian normal population were AA: 7 (9.4%), GA: 41 (54.6%), and GG: 27 (36%).
Conclusion: Significantly higher HDL cholesterol was detected in people with GG allele (P=0.02) as compared with GA and AA alleles. 866 UCP2 G/A genotype frequencies in our study were significantly different as compared with Japanese population but no with European studies that may emphasize on genetical similarity between Iranian and European Caucasians populations.
Javad Heidari, Bagher Larijani,
Volume 6, Issue 4 (17 2007)
Abstract
It is estimated that there are 1.1-1.5 billion Muslims worldwide, and prevalence of diabetes is approximately 4.6%. Many patients with diabetes insist on fasting during Ramadan, thereby creates a medical challenge for themselves and their physicians. These patients are susceptible to diabetic complications such as hypoglycemia and hyperglycemia. It is therefore important that medical professionals be aware of potential risks that may be associated with fasting during Ramadan. Patients who insist on Ramadan fasting be assessed before Ramadan and receive appropriate education and instructions related to physical activity, meal planning, glucose monitoring, and dosage and timing of medications. In this article, management of diabetes in Ramadan is discussed.
Bahareh Heidari Sharif Abadi, Farzaneh Taghian,
Volume 17, Issue 6 (10-2018)
Abstract
Background: The purpose of this study was to determine the effect of 10 weeks of Intensity Interval Training and Supplementation green tea on serum level of irisin and insulin resistance in obese women with type 2 diabetes
Methods: In this semi-experimental study,48 women with type II diabetes (aged 49/55±3/04 years with Weight 76/72±5/78 kg, Height 153/33±5/06 Cm, BMI 31/75±1/41 Kg/m2, selected and grouped randomly into four groups the intensity interval training (n=12), combined (green tea extract along with intensity interval training) (n=12) green tea extract (n=12), and the control group(n=12). Training group performed training programs including 3sessions per week at maximum intensity of 75-85% heart rate and the supplement group consumed 3 tablets of green tea (500 mg) daily for 10 weeks high intensity interval training and the supplement group both underwent intervention. Blood samples were collected before and after the intervention in fasting state. The obtained data was analyzed using of variance (ANOVA) and Tukey post hoc test and paired t-test analysis. The significant level was P<0/05.
Results: The results showed that irisin levels and maximum oxygen consumption in all three groups increased significantly after 10 weeks compared to the control group (P≤0.05) Also, the results indicate a significant increase in irezin in the combined group compared with the green tea group. Serum insulin level, glucose, insulin resistance and weight, body mass index decreased significantly in all three groups compared to control group and green tea group and combination group (P≤0.05).No significant difference was found between the groups in the irisin levels)P>0.05).
Conclusion: Regarding the results of this study, it seems that performing periodic exercises along with supplementation of green tea due to increased irisin and glucose reduction can be helpful in improving insulin resistance in patients with type 2 diabetes. Perhaps the desired results can be achieved by increasing the duration of exercise and supplementation with iyrosin and the maximum oxygen intake.
Saeedeh Rahnama Falavarjani, Azizeh Asadzadeh, Fatemeh Heidarian Naini,
Volume 18, Issue 1 (1-2019)
Abstract
Background: Inhibitors of α-glucosidase by interfering with digestion of carbohydrates play a role in controlling diabetes. Thymus vulgaris is an herb belonging to the mint family (lamiaceae). The essence of this plant contain the phenols such as thymol and carvacrol, cymene, linalool, pinene. The aim of this study was to investigate the inhibitory effect of the constituents of the thymus vulgaris extract on the activity of α-glucosidase enzyme by molecular docking.
Methods: In this study, to investigate how the compounds are attached to the active site of the enzyme, mapping of chemical structure of the compounds, energy optimization, docking studies and final analysis were carried out by ChemDraw, HyperChem, AutoDock 4.2, DS Visualizer and Lig Pluto software, respectively.
Results: All of the studied compounds were able to occupy the active site of the enzyme, among all of them, the best results of docking was related to the combination of Caryophlla-4- (12), 8 (13) -dien-5-β-ol. In fact, this compound has the most negative energy level of connection, the highest affinity for binding to the active site of the enzyme and the interaction site is similar to that of the co-crystal molecule.
Conclusion: considering the high efficacy of plant extract compounds in the bioinformatics study, and for complementary studies, the effect of the extract of this plant can be analyzed in order to control the increase of glucose in vitro and in vivo conditions.
Saeid Shamlou Kazemi, Ali Heidarianpour,
Volume 23, Issue 3 (9-2023)
Abstract
Background: During menopause, women are more exposed to the risk factors of many diseases, including metabolic syndrome, and sirtuin-1 may be involved in this disorder. The aim of this study was to investigate the effect of circular resistance training and moderate intensity continuous training on metabolic indices and Sirtuin1 serum level in women with metabolic syndrome.
Methods: This study was conducted as a clinical trial in women with metabolic syndrome in two intervention groups (15 people in resistance training group and 15 people in continuous training group) and a control group (15 people). The intervention group underwent an exercise program for eight weeks and three sessions per week, and the control group had their own routine program. After the last training session, serum levels of Sirtein1 and lipid factors were measured. To analyze the data, t-test and covariance were used at a significant level (P≤0.05).
Results: The results of the t-test showed that there was a significant difference in the intra-group changes of the studied variables (SIRT1, HDL, LDL, TG, FBS, Total Cholesterol) in both exercise groups (P≥0.05), but in No significant difference was observed in the control group (P<0.05). The results of the covariance test showed that there is a significant difference between the three groups in the indices (SIRT1, HDL, LDL, TG, FBS, Total Cholesterol) after the test (P<0.05).
Conclusion: Eight weeks of circular resistance training program and continuous training with moderate intensity has a positive effect on metabolic indices and serum level of Sirtuin1 in people with metabolic syndrome.
