Showing 4 results for Keyvan
Shima Keyvan, Noshiravan Khezri Moghadam, Asadollah Rajab,
Volume 17, Issue 2 (3-2018)
Abstract
Background: Diabetes is one of the most prevalent chronic illness that is closely associated with some psychological problems, particularly stress. In this case, psychological interventions can be useful. The aim of this study was to investigate effectiveness of Mindfulness Based Stress Reduction (MBSR) on psychosocial adjustment to illness in patient with type 2 diabetes.
Methods: In this study, semi-experimental method (pre-posttest) with control group was used. Population of the study included patients with type 2 diabetes that were member of Iranian Diabetes Society of Tehran. For sampling, 60 patients with type 2 diabetes were considered and then divided in two groups based on random sampling method. Psychosocial Adjustment to Illness Scale was used.
Results: ANCOVA showed that MBSR significantly effect on psychosocial adjustment to illness. Additionally, the results showed that MBSR significantly effect on attitude towards the disease and the social environment (P<0.05).
Conclusion: Findings revealed that MBSR can be effective on increasing psychosocial adjustment to illness in patients with type 2 diabetes. These findings have been inferred that patients with type 2 diabetes need to increase their psychosocial adjustment to illness.
Mousa Khalafi, Amir Ghanbarpour Nosrati, Keyvan Sharifmoradi,
Volume 23, Issue 4 (11-2023)
Abstract
Background: Fetuin-A, as a hepatokine, plays an important role in the regulation of whole-body metabolism, which is increased with chronic diseases. Therefore, the aim of this meta-analysis is to investigate the effect of exercise training on Fetuin-A levels in individuals with metabolic and kidney diseases.
Methods: A systematic search was conducted in PubMed, Web of Science, and Google Scholar databases until November 2022 using the keywords "exercise training" and "Fetuin-A". To determine the effect size, standardized mean difference (SMD) and 95% confidence interval were calculated using CMA2 software. Heterogeneity was evaluated using the I2 test, and publication bias was evaluated by visual interpretation of the funnel plot and Egger's test. The quality of the included studies was evaluated using the PEDRO checklist.
Results: A total of 16 studies including 21 trials arms and 554 subjects with type 2 diabetes, obesity and kidney disease were included in the meta-analysis. Exercise training resulted in a significant decrease in Fetuin-A levels [-0.93 (CI: -1.35 to -0.51) P= 0.001]. There was a high heterogeneity (I2= 89.24, P= 0.001) and also a significant publication bias (P= 0.001). The results of subgroup analysis based on the type of exercise training showed that aerobic training resulted in a significant decrease in Fetuin-A (P= 0.001) while the reduction of this marker with combined training was not significant (P= 0.33).
Conclusion: Exercise training, especially aerobic training, results in a decrease in Fetuin-A levels in metabolic patients, which may be contributed to the beneficial effects of exercise.
Abdullah Alauddin Ahmed Al-Ma'amouri,, Keyvan Sharifmoradi, Mousa Khalafi, Zahra Pezeshki,
Volume 25, Issue 1 (4-2025)
Abstract
Background: The purpose of this study was to investigate the effect of two types of interval and continuous training on apolipoprotein M, TNF-α and IL-6 of visceral fat in rats fed a high-fat diet.
Methods: Twenty-four male Wistar rats were randomly divided into four groups including standard diet (ND), high-fat diet (HFD), high-fat diet with moderate intensity continuous exercise (HFD+MICT), high-fat diet with high intensity interval training (HFD+HIIT). The HIIT and MICT groups performed their group specific training for 8 weeks, 5 sessions per week. The HIIT protocol consisted of 6 bouts of 4-minute exercise at 85-90% of the maximum speed, which had a 2-minute active rest, and the MICT protocol performed at 65-70% of the maximum speed. Protein levels of apolipoprotein M, TNF-α and IL-6 in visceral fat were measured using western blot method.
Results: Eight weeks of HFD increased the protein levels of apolipoprotein M, TNF-α, and IL-6 in visceral fat compared to the ND group (P< 0.05). In contrast, both HIIT and MICT protocols led to a significant reduction of visceral fat IL-6 compared to the HFD group (P= 0.001). Also, MICT caused a significant decrease protein levels apolipoprotein M compared to the HFD group (P= 0.04). However, both exercise protocols had no significant effect on TNF-α (P< 0.05). Also, there was no significant difference between training groups (P< 0.05).
Conclusion: Exercise training improves adipose tissue inflammatory markers in high-fat diet-fed rats, and moderate-intensity continuous training may be a more appropriate approach.
Mahin Nomali, Mahdi Mazandarani, Narges Lashkarbolouk, Mohammad Reza Mohajeri Tehrani, Neda Mehrdad, Keyvan Salehi, Amir Mahdi Raeisi, Orod Jalali, Shiva Armani Moghadam, Pedram Pirmoradian, Mohammad Reza Amini,
Volume 26, Issue 2 (7-2026)
Abstract
Background: Since 1999, the International Working Group on the Diabetic Foot (IWGDF) has consistently provided evidence-based guidelines aimed at the prevention and management of diabetic foot (DF). The latest version of these guidelines was published in 2023. Despite similarities such as being compiled by a working group, based on systematic reviews, and using the GRADE methodology to grade recommendations, it has some differences from the 2019 version. Awareness of these similarities and differences facilitates the faster implementation of evidence into clinical practice. The aim was to compare the similarities and differences between the 2019 and 2023 versions of the IWGDF guidelines.
Methods: In this comparative review study, both guideline versions were reviewed as primary sources. Data were extracted in two domains: structural (methodology) and content (number of chapters and recommendations, and key points). A comparison was then conducted on the data both quantitatively and qualitatively, whereby the similarities and differences between the two versions were identified and analyzed by juxtaposing the extracted information.
Results: The 2019 version consists of six guidelines, while the 2023 version includes seven separate guidelines. Both versions contain individual guidelines for prevention of foot ulcers (14 recommendations in 2023 vs. 16 in 2019), classification of foot ulcers (5 recommendations in both versions), diagnosis and treatment of foot infections (26 recommendations in 2023 vs. 27 in 2019), diagnosis and treatment of peripheral artery disease (25 recommendations in 2023 vs. 17 in 2019), offloading interventions (12 recommendations in 2023 vs. 9 in 2019), and wound healing interventions (29 recommendations in 2023 vs. 9 in 2019). A significant difference in the 2023 version compared to 2019 is the addition of a guideline for the diagnosis and treatment of active Charcot neuro-osteoarthropathy, which includes 26 recommendations.
Conclusion: Despite content similarities, the 2023 version differs from the 2019 version in the number of recommendations, with the most notable difference being the inclusion of a guideline for the diagnosis and treatment of active Charcot neuro-osteoarthropathy.
