Showing 5 results for Khaleghi
Mohamad-Hasan Bastan Hagh, Bagher Larijani, Ali-Reza Khalilyfard, Arash Hossein-Nezhad, Ramin Heshmat, Nasim Khaleghian, Gazal Khoshechin,
Volume 3, Issue 1 (16 2004)
Abstract
Diabetes mellitus (DM) is the commonest cause of renal failure, blindness and non traumatic amputation. According to ADA, prevention of DM complications is possible through monitoring and control of blood glucose levels.
Methods: The Betachek strip, produced in Australia, is able to determine biood glucose level with no need for electronic glucometer devices.
Results: In this study, we compared venous and capillary blood glucose levels as determined by lest strips with measurements of enzymatic method (the standard laboratory kit). The mean capillary and venous blood glucose measured by the strip test was 21.85 mg/dl (P< 0.0001) and 17.9 mg/dl (P< 0.002) respectively that was 11.13% more than the standard method.
Conclusion: In this study, standard method had higher correlation with venous samples glucose level, than capillary samples (as measured by Betachek) (0.84 vs. 0.824). This difference was statistically significant (P< 0.0001).
Good correlation between the Betachek strip and the standard enzymatic method of blood glucose measurements, advocate its usage in home setting.
Mohsen Khoshniat Niko, Farah Madarshahian, Mohsen Hassanabadi, Ramin Heshmat, Nasim Khaleghian,
Volume 7, Issue 1 (18 2007)
Abstract
Background: Increasing number of people with diabetes make it the greatest world-wide epidemy which indicates importance of education in physical and mental health of the patients. Since researches report different results about cognition status of diabetic patients, this study was conducted to determine and compare cognitive status in older people with and without type 2 diabetes.
Methods: In this case- control study 80 patients with type 2 diabetes mellitus compare with 80 persons without diabetes. Cases were selected from the patients refer to diabetes outpatient clinic and control group were patients referred to other clinics. Instruments were questionnaire for gathering demographic data, glucometer, DSM-IR-TR questionnaire, FBS for control group and TSH - T4- HbA1c for cases..
Results: The mean scores of MMSE were 23.3 and 26.8 in case and control group respectively. Difference between two groups was significant in MMSE scores (P<0.01), furthermore between men and women of two groups (P<0.01 for both). No significant difference of MMSE scores between men and women in case group was seen (P=0.45). There was negative association between MMSE scores and age also duration of illness according to the results.
Conclusion: Elderly diabetic patients encounter some cognitive impairment which is exacerbated with increasing age.
Iraj Khaleghi, Eidy Alijani, Alireza Rahimi, Mahsa Mohsenzade,
Volume 21, Issue 3 (9-2021)
Abstract
Background: Diabetes disorders can lead to muscular burnout. The aim of this study was to determine the simultaneous effect of resistance training and endothelial stem cell injection on the factor of degeneration in the muscles of diabetic rats.
Methods: 36 male wistar rats (age 6 weeks with weight of 20±200g) were randomly divided into five groups of basic healthy, diabetic control (D), diabetic and resistance training (DR), untrained diabetic by injection of endothelial stem cells (DI), diabetic training by simultaneous injection of endothelial stem questions (DRI). Western blotting and insulin resistance index were measured by ELISA method to evaluate the changes in MURF1 expression. The data were analyzed by two-factor analysis of variance by SPSS software version 19 at a significant level of α≥%5.
Results: In this study, 6 weeks of resistance training significantly reduced MURF1 and insulin resistance index. The interactive effect of resistance training and stem cell injection also resulted in a significant decrease in murf1 levels, but insulin resistance index was not significantly superior to only training or injection.
Conclusion: Based on the findings of this study, it can be stated that resistance training or injection of endothelial ancestral cells can improve muscular degeneration, but simultaneous use of these two strategies was not superior in reducing atrophy complications in diabetic rats.
Iraj Khaleghi, Eidy Alijani, Alireza Rahimi, Mahsa Mohsenzadh,
Volume 22, Issue 1 (4-2022)
Abstract
Background: Diabetic disorders can lead to muscle atrophy. The aim of this study was to investigate the combination of resistance training and endothelial progenitor cell injection on the expression of horseshoe muscle atrophy factor in diabetic rats.
Methods: 30 rats (6 weeks old weighing 200 20 200 g) were randomly divided into five groups: healthy baseline, control diabetic, trained diabetic, non-trained diabetic by endothelial progenitor cell injection, diabetic trained by simultaneous injection Endothelial progenitor cells were divided. Heat 25 was measured by Western blotting to evaluate changes in protein expression. Data were analyzed by two-factor analysis of variance test by SPSS software version 19 at a significance level of α≥ 5%.
Results: In this study, 6 weeks of resistance training had no significant effect on the expression of heat shock protein 25. But injection of endothelial progenitor cells resulted in a significant increase in the expression of heat shock protein 25. The interactive effect of resistance training and progenitor cell injection on heat shock protein 25 was not significant, in other words, there was no significant superiority over training and injection at the same time as training or injection alone.
Conclusion: Based on the findings of this study, it can be stated that injection of endothelial progenitor cells can improve muscle wasting but resistance training alone was not effective. Also, the combination of these two strategies was not superior in reducing the complications of atrophy in diabetic rats.
Mehdi Changizi, Rozita Fathi, Rostam Ali Zadeh, Seyed Mohsen Avandi, Ali Khaleghian,
Volume 24, Issue 6 (2-2025)
Abstract
Background: Obesity is known to have metabolic complications including insulin resistance (IR) and metabolic disorder. The aim of this study was to compare the effect of two traditional 12-week circular resistance training methods on the levels of branched and aromatic amino acids and insulin resistance of overweight and obese men.
Methods: The current research method is of the clinical trial type, with Thirty-three overweight and obese men with mean and standard deviation of age, weight and body mass index were 17.7±0.13 years, 92±2.45 kg and 30.70±32 1.32 kg / m2, respectively. They were selected and randomly divided into three groups: circular resistance training (n= 11), traditional resistance training (n= 11) and control (n= 11). The training program consisted of two traditional resistance training protocols and 12-week wave circuits that were exactly the same volume; Which was run three times a week. Blood sampling was performed 48 hours before and after the training protocol and after 8 hours of fasting. HPLC was used to measure serum levels of amino acids.
Results: The results of analysis of variance in the groups showed that circuit training more than 2 times compared to traditional training reduces total BCAAs (35.9 vs. 15.5%) and AAAs in serum (19.5 vs. 9%) and equally the level of insulin resistance. (23 and 26.7 percent, respectively) reduced the door in overweight and obese young men.
Conclusion: The results of this study showed that the level of changes in circular resistance training was higher than traditional. Circular resistance training may be able to prevent obesity-related metabolic disorders.
