Showing 9 results for Khoshniat
Ehia Garshaspi, Seied Mohsen Khoshniat Nikoo, Mariam Abbasian, Bita Radjabipour, Nader Fallah,
Volume 4, Issue 1 (17 2004)
Abstract
Background: Currently different criteria are used to diagnose Gestational Diabetes. ACOG (American college of obstetric and Gynecology) accepted NDDG's (criteria National Diabetes Data Group) Criteria and ADA (American Diabetes Association) accepted Carpenter Caustan’s. Although both of these criteria have been achieved by O Salivan and Mahan’s reaserches, the number of patients has been diagnosed are different .The aim of this study was to compare Gestational Diabetes prevalence according to Carpenter Caustan’s and NDDG’s Criteria.
Methods: 1200 pregnant women were screened in a prenatal care clinic. Patients with definite diabetes were excluded. According to universal GDM screening method, for all of the patients GCT and GTT (if GCT > 130) were preformed. The results evaluated according to Carpenter Caustan’s and NDDG’s criteria.
Results: In this screening, 377 participants had positive GCT, according to Carpenter and Caustan’s criteria 83 women (6.9%), and according to NDDG criteria 50 women (3.6%) had Gestational Diabetes Mellitus. If the cut of point of GCT was 140 mg/dl instead of 130 mg/dl, according to Carpenter and Caustan’s criteria 16 women (18.1%), and according to NDDG 4 patients (9%) were missed.
Conclusion: Regarding the significant difference between two methods in diagnosis of gestational diabetes mellitus, assessment of each method value in improving prognosis and outcomes is necessary. According to the results the cut of point of 130mg/dl, as recommended in previous studies, has more accuracy for screening.
Jila Maghbouli, Arash Hoseinnejad, Mohsen Khoshniatnikoo, Seyed Masoud Arzaghi, Mazaher Rahmani, Bagher Larijani,
Volume 6, Issue 1 (19 2006)
Abstract
Background: Few studies have investigated maternal leptin concentrations in women with pregnancies complicated by gestational diabetes mellitus (GDM), and these published results are conflicting. We examined the association between plasma leptin concentration and GDM risk.
Methods: As a cross-sectional study 741 pregnant women that referred to five university hospital clinics were recruited. The universal screening was performed with a GCT-50g and those with plasma glucose level ≥130mg/dl, were diagnosed as GDM if they had an impaired GTT-100g based on Carpenter and Coustan criteria. The level of insulin was measured during OGTT-100g. Also maternal plasma leptin concentrations were measured.
Results: GDM patients had higher age, parity, BMI, and serum leptin concentration as compare with normal pregnancies. In logistic regression model serum leptin levels were independent factor for GDM.
Conclusion: Serum leptin concentrations can predict GDM.
Atbin Moradi Zirkohi, Mohsen Khoshniat, Farhad Zare, Zhila Maghbooli, Arash Hossein-Nezhad, Alireza Shafaei, Bagher Larijani,
Volume 6, Issue 2 (18 2006)
Abstract
Background: Adiponectin and leptin are hormones which are related to body fat tissues and body weight. In pregnant women, conflicting associations have been reported between the role of serum concentrations of adiponectin and leptin with infant birth weight. The aim of this study was to determine the association between maternal and cord blood adiponectin and leptin concentrations with birth weight.
Methods: As a cross-sectional study 86 pregnant women referred to university hospital clinics were recruited. Maternal and umbilical cord blood samples were obtained in delivery room just after birth. The maternal and umbilical cord serum samples were analyzed for adiponectin and leptin. Their birth weight and height were measured at labor.
Results: The mean of maternal BMI, birth weight, and gestational age was 23.8±4.8 kg/m2, 3.13±0.14 kg, and 38.15±2.6 week, respectively. No correlation between adiponectin and birth weight were found. Birth weight positively correlates with leptin.
Conclusion: leptin concentrations in cord blood may be reflected the alternation of body fat tissue in infant and independently associated with infant birth weight.
Mahin Valikhani, Mohsen Khoshniat Niko, Ali Naser Tork,
Volume 6, Issue 3 (17 2007)
Abstract
Background: Pemphigus vulgaris is the most common autoimmune blistering disease. Corticosteroid is treatment of choice for it. Medication can affect many organs and causes metabolic difficulties which steroid- induced diabetes (SID) is one of the most important side effects. Determining risk factors not only help identify diabetes in early stages but also let continuing treatment of underlying disease.
Methods: Sixty eight patients with recently diagnosed pemphigus vulgaris were recruited. After admitting in hospital they were evaluated for positive family history of diabetes, blood pressure, body mass index (BMI), FBS, HbA1c, TG and HDL. Then they followed with FBS twice per week for 8 weeks.
Results: Ninety patients (27.9%) developed diabetes. In comparison with non-diabetic group, diabetic group had a significantly higher HbA1c>6% (NL: 4.5-6.8) or: 8.39 (CI: 1.46- 48.05), TG > = 200 or: 6.56 (CI: 1.64-28.18) and IFG or: 3.11 (CI: 1.04-9.31). There were no differences between the groups in respect of age, positive family history, blood pressure, BMI, HDL.
Conclusion: These findings suggest that HbA1c,TG and IFG are independent risk factors so patients with pemphigus vulgris who are candidates for steroid treatment should be evaluated for HbA1c, TG and IFG before treatment.
Mohsen Khoshniat, Zahra Komeylian, Mansoureh Moadi, Maryam Peimani, Ramin Heshmat, Reza Baradar Jalili, Bagher Larijani,
Volume 6, Issue 4 (17 2007)
Abstract
Background: Children with Type 1 diabetes were present one of the greatest challenges in the worldwide. Health-care providers must be sufficiently aware of diabetes so that such children make utmost benefit of their educational opportunities. The aim of the present study was to compare the effect of three educational methods in raising the level of knowledge of school health-care providers. Therefore the best method would be applied for this purpose.
Methods: In this interventional study 132 samples were randomly chosen from the list of school health care providers of Tehran and divided to the three groups (educated by posters, booklets, and group education). A questionnaire was completed for all the three groups before and after the education. Questionnaire consisted of two parts: -demographic information and 16 questions about diabetes information. Scores were analyzed by descriptive and inferential methods (T-test, ANOVA).
Results: The level of knowledge of school health-care providers was weak in 23.5% of the case, average in 59.8% of cases, and good in 16.7% of cases. The level of knowledge in the groups educated by booklets and group education increased meaningfully, while no obvious increase was observed in the group trained via posters.
Conclusion: From the three aforementioned training methods, group education and education by booklets have the most effect on raising the level of knowledge of health-care providers.
Mohsen Khoshniat Niko, Farah Madarshahian, Mohsen Hassanabadi, Ramin Heshmat, Nasim Khaleghian,
Volume 7, Issue 1 (18 2007)
Abstract
Background: Increasing number of people with diabetes make it the greatest world-wide epidemy which indicates importance of education in physical and mental health of the patients. Since researches report different results about cognition status of diabetic patients, this study was conducted to determine and compare cognitive status in older people with and without type 2 diabetes.
Methods: In this case- control study 80 patients with type 2 diabetes mellitus compare with 80 persons without diabetes. Cases were selected from the patients refer to diabetes outpatient clinic and control group were patients referred to other clinics. Instruments were questionnaire for gathering demographic data, glucometer, DSM-IR-TR questionnaire, FBS for control group and TSH - T4- HbA1c for cases..
Results: The mean scores of MMSE were 23.3 and 26.8 in case and control group respectively. Difference between two groups was significant in MMSE scores (P<0.01), furthermore between men and women of two groups (P<0.01 for both). No significant difference of MMSE scores between men and women in case group was seen (P=0.45). There was negative association between MMSE scores and age also duration of illness according to the results.
Conclusion: Elderly diabetic patients encounter some cognitive impairment which is exacerbated with increasing age.
Mahdieh Akhoundan, Zhaleh Shadman, Nooshin Poorsoltan, Mozhdeh Soleymanzadeh, Mohsen Khoshniat Nikoo, Bagher Larijani,
Volume 13, Issue 4 (5-2014)
Abstract
Background: Fasting in diabetic patients is accompanied by various changes in metabolism, lifestyle and medication. Evaluation of diabetic patients’ knowledge in the field of fasting conditions, the fasting-induced changes, complications, and ways to deal with them, is the first step towards efficient and effective diabetes self-management training in Ramadan fasting. The purpose of this study was to design a valid and reliable questionnaire on fasting knowledge of diabetic patients and evaluate the knowledge and determinant factors in diabetic patients.
Methods: In this study a questionnaire on diabetic patient’s awareness was designed in 5 sections: 1- fasting conditions in patients with diabetes (fasting status of diabetic patients), 2- drug use, 3- controlling of blood glucose, 4- physical activity and 5- diabetic diet in Ramadan. Validity and reliability (Cronbach's alpha coefficient=0.79) of the questionnaire was confirmed. In a cross-sectional study, the fasting knowledge of 200 diabetic patients of Diabetes and Metabolic disorders clinic were examined, before Ramadan 2012. The association between the knowledge and patients’ age, sex, weight, diabetes duration, educational levels, Ramadan fasting group education, fasting blood sugar, HbA1c and type of diabetes were evaluated.
Results: The mean of total correct answers were 46% with the highest scores in dietary information (62.5%) and lowest in physical activity (18%) and drug use (23%). Significant positive association was found between total and each part scores with patients’ educational level. Also group of participating in the Ramadan fasting education study and group of non- participating, showed significant difference in response to questions.
Conclusion: Findings of this study revealed (indicated) poor fasting knowledge in diabetic patients. Educational programs before Ramadan can increase awareness and could improve self-management of diabetic patients during Ramadan fasting and decrease complications.
Nima Baziar, Kurosh Djafarian, Zhaleh Shadman, Mostafa Qorbani, Mohsen Khoshniat Nikoo, Farideh Razi,
Volume 13, Issue 5 (7-2014)
Abstract
Background: Vitamin D deficiency is associated with impaired insulin secretion, glucose intolerance and type 2 diabetes. This study was conducted to investigate the effects of supplementation with 50,000 IU vitamin D on improving serum vitamin D levels and insulin resistance in vitamin D insufficient or deficient type 2 diabetic patients.
Methods: In this double blind randomized clinical trial, 81 type 2 diabetic patients with vitamin D levels between 10-30 ng/ml were randomly assigned to intervention (50,000 IU vitamin D3 once a week) and control (placebo once a week) groups according to gender. The study duration was 8 weeks. At the beginning and the end of study, blood samples were collected after 12 hours overnight fasting and fasting serum glucose, insulin and 25-hydroxyvitamin D were measured. Insulin resistance was obtained by HOMA-IR calculation.
Results: After 8 weeks supplementation with vitamin D, 25-hydroxyvitamin D level was significantly increased and reached to normal levels in the intervention group. Fasting serum glucose and insulin concentrations and HOMA-IR were significantly decreased in the vitamin D group, but there were no significant changes in the placebo group.
Conclusion: Supplementation with 50,000 IU vitamin D for 8 weeks compared to placebo can improve inadequate levels of vitamin D and glycemic indicators in vitamin D insufficient or deficient type 2 diabetic patients.
Nooshin Poorsoltan, Yadollah Mehrabi, Zhaleh Shadman, Mahdieh Akhoundan, Arash Rashidi, Mohsen Khoshniat Nikoo,
Volume 14, Issue 1 (1-2015)
Abstract
Background: Physiological stress may affect eating habits and also foods intake may alter the physiological stress. According to the reports of high levels of serum cortisol as a stress biomarker in type 2 diabetic patients the aim of this study was to investigate the relationship between dietary patterns and serum cortisol concentration in type 2 diabetic patents.
Methods: This cross-sectional study was conducted on 241 type 2 diabetic patients in 2013. Major dietary patterns were obtained by factor analysis. Serum cortisol was measured at 8 am. Serum cortisol level was compared among tertiles of dietary patterns using ANCOVA adjusted for confounders (age, sex, BMI, and fasting blood glucose). Linear regression analysis was performed to assess the association between serum cortisol and scores of dietary patterns.
Results: Three major dietary patterns were identified as Western, healthy and healthy like. None of the variables age, waist circumference, body mass index, physical activity level, duration of diabetes and fasting blood glucose was significantly associated with serum cortisol. After adjustment for confounders, no statistically significant difference was found in mean serum cortisol among tertiles of dietary patterns or no statistically significant association between serum cortisol and dietary patterns scores. Mean serum cortisol was 12.95±5.10 nmol/L which was in normal range.
Conclusion: This study showed that in type 2 diabetic patients, normal levels of serum cortisol were not associated with the adherence to Western, Healthy and Healthy like dietary patterns.
