Iranian Journal of

Background: Nesfatin-1 is an adipokine that released by adipose tissue and participated in the regulation of insulin activity and glucose metabolism. The aim of this research is the investigation the effect of 10 week resistance exercise training on serum levels of nesfatin-1 and insulin resistance index in women with type 2 diabetes. Methods: Eighteen women with type 2 diabetes recruited this study by using of the Purposive Sampling method and were randomly divided into two experimental (n= 10) and control (n= 8) groups. The experimental group participated in resistance exercise training (the exercises training started with 30-50% intensity of one maximum repetition in the first training session and increased to 70-80% intensity of one maximum repetition in the final session) in three times per week for 10 weeks. Also, the control group not participated in exercise program. Blood samples were taken pre-and post-exercise test in the 12 h fasting conditions for evaluation of nesfatin-1, insulin and glucose levels. The resulting data was analyzed by SPSS 21 and used of Kolmogorov-Smirnov, t-independent and dependent t-tests at a significance level of &alpha<0.05. Results: Intra-group changes in the experimental group showed that a significant increase in nesfatin-1 levels and a significant reduction in blood glucose and insulin resistance levels after 10 weeks resistance training (P<0.05). However, there was no significant change in insulin levels (P>0.05). In the comparison between groups, the changes of nesfatin-1 and glucose levels were significantly in pre- and post-exercise test in the experimental group compared with the control group (P<0.05). Conclusion: According to the results of this research, resistance exercise training could be recommended as adjunctive therapy method for women with type 2 diabetes.

Background: Omentin-1 is recognized as new Adipokine that mostly is excreted from visceral fatty tissue. Circulating levels of Omentin-1 are inversely associated with obesity. The aim of the present study on two training methods of endurance and resistance on Omentin-1 levels of plasma and factors related to obesity and overweight in obese girls, respectively.

Methods: Thirty four obese and overweight girls (BMI>25) were chosen purposefully then they were categorized at random to three endurance group (n=12), resistance group (n=12) and control (n=10). A total of 8 weeks of endurance and resistance training and endurance training was 4 times a week with 65 to 80 percent of HRmax and intensity resistance training was 65-80% of 1RM. Phlebotomizing was done at various stages with similar conditions and plasma Omentin-1 levels by ELISA method was measured. Data were analyzed by Kolmogorov-Smirnov and related t tests for studying the changes within the ANOVA and LSD post Hoc test for comparison between groups at the significance level of p<0.05.

Results: The results showed a significant increase Omentin-1 in both the experimental group (p _endurance =0.001, p _resistance =0.004) and reduce factors associated with obesity such as weight (p _endurance =0.003, p _resistance =0.005), fat mass body (p _endurance =0.001, p _resistance =0.001), BMI (p _endurance =0.002, p _resistance =0.004) and WHR (p _endurance =0.011, p _resistance =0.013) in both experimental groups after 8 weeks of training (p<0.05).

Conclusion: It can be stated that both endurance and resistance practices after 8 weeks of training, to improve factors related to obesity, maximal oxygen uptake and increased plasma levels Omentin-1 was.

Background: Omentin-1 is known as adipokines that are secreted by visceral fat tissue. Omentin-1 levels are inversely associated with obesity. The aim of this research was investigation of the effect of Rhythmic aerobic exercise on serum concentration of Omentin-1 and same Anthropometric markers in obese women.

Methods: Thirty two obese women voluntarily selected with mean age 37± 8 years old and body mass index of  32.34±3.54 kg/m² and randomly were divided into two groups of experimental (n=17) and control group (n=15). Subjects in the experimental group performed the exercise training with intensity 80-70% of maximum heart rate for 45-60 minutes per session, three times a week for 10 weeks. The control group did not participate in any exercise program. Omentin-1 serum levels, weight, body mass index and waist-to-hip ratio was calculated before and after exercise. Collected data were analyzed by using of Shapiro-Wilk, Leven, dependent t test and analysis of covariance (ANCOVA) with software SPSS version 21 in significant level of α<0.05 or α<0.001.

Results: 8 week aerobic exercise in the experimental group was associated with a significant increase in the omentin-1 levels (P=0.0001) and significant reduction of weights and body mass index (p= 0.0001) (P<0.05). Whereas there was no significant change in WHR levels (P>0.05). Reviews for between group indicated a significant increase in the amount of omentin-1 (P=0.009) and a significant reduction in weight values (P=0.0001) and BMI (P=0.001) in the experimental group compared with the control group (P<0.01).

Conclusion: It seems that rhythmic aerobic exercise is an important role in improving cardiovascular health and obesity-related disorders in obese women by increasing omentin-1 and reducing obesity-related factors.