Showing 2 results for Mosaferi
Atefeh Ketabdar, Seyed Reza Attarzadeh Hosseini, Mehrdad Fathei, Mohamad Mosaferi,
Volume 23, Issue 5 (12-2023)
Abstract
Background: Fatty liver disease and its relationship with cardiovascular diseases is one of the concerns of today's society, therefore the present study was conducted to investigate the effect of eight weeks of endurance training and growth hormone injections on Cardiac mitochondrial PGC1α content and some oxidative stress indices in mice with hepatic damage.
Methods: In this experimental study, 21 male mice were, randomly, divided into three groups (n=7): control (C), Exercise (E), Exercise + Growth Hormone (EGH) group. The Medium intensity endurance training program was performed for eight weeks and 5 sessions with an intensity of 50% VO2max of per week. The somatropin injection protocols were 1 mg/ kilogram/body weight, respectively. Statistical analysis of the data was performed using the software SPSS, using One-Way ANOVA and post hoc Tukey tests.
Results: PGC1a levels increased in both groups compared to the control group. SOD and MDA levels increased and decreased in both groups compared to the control group, respectively. The reduction of HOMA levels was significant only in E group compared to the control group. Also, the difference between E and E-GH group was significant. ALT/AST ratio decreased in both groups compared to the control group. The reduction of LDL/HDL ratio was significant only in group E compared to the control group.
Conclusion: Endurance training has produced a more effective response in improving NAFLD markers than GH peptides. Growth hormone injection can have negative consequences on some indicators of this abnormality.
Bizhan Hooshmand Moghadam, Amir Rashidlamir, Mohammad Mosaferi Ziaaldini,
Volume 24, Issue 5 (12-2024)
Abstract
Background: Exercise interventions can play an important role in improving metabolic status by regulating hepotokines. The present study aimed to investigate the effect of eight weeks of Jump Rope Interval Training on serum levels of Fetuin-A and insulin resistance in overweight and obese young men.
Methods: In this semi-experimental study, 26 overweight and obese young men (body mass index: 28.24±1.66) were voluntarily and purposefully selected as a statistical sample and randomly divided into two experimental (n= 13) and control (n= 13) groups. The participants of the experimental group performed Jump Rope Interval Training for 8 weeks (four sessions per week/40 minutes each session). At the beginning and end of the study, venous blood samples were collected to measure Fetuin-A and insulin resistance. Data analysis was done using SPSS software version 24 and with dependent and independent t-tests at a significance level of less than 0.05.
Results: After 8 weeks of Jump Rope Interval Training, a significant decrease was observed in serum levels of Fetuin-A, insulin resistance and, body fat percentage (P≤ 0.05). Also, a significant difference was observed between the experimental and control groups in serum levels of Fetuin-A, insulin resistance and, body fat percentage (P≤ 0.05).
Conclusion: According to the results of the present study, it seems that regular jump rope interval training for eight weeks can effectively improve the metabolic complications in overweight and obese young men by reducing the serum levels of hepotokine Fetuin-A.
