Showing 4 results for Pejman Sani
Azin Saeidzadeh, Roya Naemi, Shahrzad Mohseni, Mahnaz Pejman Sani, Masoud Amanzadeh,
Volume 25, Issue 3 (7-2025)
Abstract
Background: Type 1 diabetes mellitus or juvenile/adolescent diabetes has a significant impact on the quality of life among children and parents. Thus, the development of a deep understanding of the disease of diabetes in childhood and the ways to prevent and treat patients allows health care providers to respond to their specific needs. One of the solutions to improve the knowledge of the patients is online education. Therefore, this study designed and evaluated a childhood diabetes education website with the goal of improving the quality of care for children and reducing mortality.
Methods: This study involved three phases of content collection, website design, and evaluation. The website content information was collected from reliable library sources and created using the WordPress website design tool. Subsequently, the website content, performance, display capabilities, terminology and information retrieval, and ease of learning were evaluated by physicians and nurses.
Results: Comprehensive clinical information about pediatric diabetes was provided on the website. In the evaluation of the website content, the highest average was related to the type 1 diabetes section at a glance and the lowest average was related to the pathology section. In evaluating the website performance, the highest average was related to the overall design and the lowest average was related to the ease of use. Overall, the website performance was of good quality.
Conclusion: To increase the effectiveness of care services and reduce the complications of diseases, providing accurate and reliable information in the form of educational websites should be considered.
Shahrzad Mohseni, Mahnaz Pejman Sani,
Volume 25, Issue 4 (9-2025)
Abstract
Osteoporosis is a metabolic bone disorder characterized by reduced bone mineral density and an increased risk of fractures. It has significant health impacts and is associated with socioeconomic consequences. Triglyceride-glucose indices [TyG, TyG-body mass index (BMI), TyG-waist circumference (WC), and TyG-waist to height ratio (WHTR)] are recognized as surrogate and cost-effective markers for assessing insulin resistance and can be effective in evaluating bone health and predicting the risk of osteoporosis and fractures. However, according to existing evidence, the relationship between these indices and bone health can be influenced by various factors such as gender, age, obesity, and metabolic disorders. There is also evidence of a nonlinear association between these indices and bone density, where their positive effect diminishes or reverses after reaching a certain threshold. These indices can serve as alternative and affordable markers for assessing bone health and early identification of individuals at risk of osteoporosis and bone fractures. Nonetheless, further longitudinal research is needed to confirm these findings across different populations and to determine the underlying mechanisms. The aim of this review study was to examine the existing evidence regarding the relationship between triglyceride-glucose indices and bone health.
Shahrzad Mohseni, Mohammadreza Mohajeri-Tehrani, Mahnaz Pejman Sani,
Volume 25, Issue 6 (1-2026)
Abstract
Blood glucose variability, defined as variations in blood glucose levels over time, is increasingly recognized as a significant factor in the pathology of diabetes complications. While chronic hyperglycemia has been linked to microvascular complications (retinopathy, nephropathy, and neuropathy) and macrovascular complications (coronary artery disease, stroke, and peripheral artery disease), emerging evidence suggests that glucose variability is an independent risk factor for these conditions. This review examined the relationship between blood glucose variability and the development of microvascular and macrovascular complications in diabetes, highlighting the underlying mechanisms, clinical implications, and therapeutic approaches.
Parisa Karimzadeh, Mahdis Khazaeli Najafabadi, Sina A Sharghi, Farzaneh Karimi Birgani, Effat Asadollahpour, Somayeh Parichehreh-Dizaji, Mahnaz Pejman Sani, Sayed Mahmoud Sajjadi-Jazi, Mahmood Naderi, Hilda Samimi, Shirzad Nasiri, Seyed Mohammad Tavangar, Bagher Larijani, Vahid Haghpanah,
Volume 25, Issue 6 (1-2026)
Abstract
Background: Biobanks are biological repositories that collect, process, store, and distribute human biological samples. Among them, tumor banks play a central role in biomedical research. The overall goal of a tumor bank is to collect cancerous and normal samples under standardized conditions for basic, clinical, or applied research.
Methods: Tumor samples from patients with endocrine neoplasms were collected from excess tissue samples not required for diagnostic purposes after surgery in the surgical department of Dr. Shariati Hospital, Tehran, Iran. In addition, relevant biological samples such as serum, plasma and DNA were collected in parallel. Prior to sampling, informed consent was obtained from the patients and a questionnaire was completed. After rapid freezing with isopentane, tissue samples were stored in a liquid nitrogen tank, while other biological materials, such as serum, were stored in a -80°C freezer.
Results: Tissue, plasma, serum, and DNA samples collected from patients with endocrine neoplasms were stored in separate barcoded storage boxes in the biobank and were made available to researchers.
Conclusion: The use of bioproducts in domestic research and international networks has strengthened research collaborations through supporting the collection and distribution of tissues, especially cancer tissues. This trend plays an important role in facilitating basic and applied research in various fields of cancer, including molecular biology, immunology, genetics and pharmacology, and will pave the way for scientific advances and therapeutic innovations.
