Showing 8 results for Ramezani
Maryam Farahmand , Fahimeh Ramezani Tehrani, Mahnaz Bahri Khomami, Fereidoun Azizi,
Volume 14, Issue 1 (1-2015)
Abstract
Background: The present study was conducted to assess the association between duration of oral contraceptive pills consumption and metabolic syndrome.
Methods: Study subjects were selected among 5532 of women 15-45 years old aged participating in Tehran Lipid and Glucose Study (TLGS). TLGS questionnaires were used for data collection.
Results: Metabolic syndrome and its components did not significantly differ between study sub groups after adjustment for confounders.
Conclusion: OCPs duration of consumption does not affect prevalence of metabolic syndrome among non menopausal women.
Fahimeh Ramezani Tehrani, Sonia Minooee, Masoumeh Simbar, Fereidoun Azizi,
Volume 14, Issue 2 (1-2015)
Abstract
Background: Considering the limited population-based studies and lack of a general consensus on the most sensitive and precise predictor of insulin resistance and metabolic syndrome in the women with polycystic ovary syndrome (PCOS), the present study was performed with the aim of comparing the validity of various available adiposity markers in these patients. Methods: In the national and population-based study of PCOS prevalence, 1772 girls and women, aged 18-45 years, were assessed for the diagnosis of PCOS based on Rotterdam criteria. Waist circumference, body mass index, waist to hip ratio, lipid accumulation product, visceral adiposity index (VAI) and homeostasis assessment model- insulin resistance (HOMA-IR) were calculated. The diagnosis of metabolic syndrome was based on Joint Interim Statement (JIS)criteria and HOMA-IR&ge 2.3 was considered as the resistance cutoff point. Results: In among different markers, VAI served as the best predictor of insulin resistance (sensitivity %60, positive predictive value %83) and metabolic syndrome (sensitivity %97, positive predictive value %95). ROC curve showed the cutoff points of 1.8 and 3.1 as the optimum values for insulin resistance and metabolic syndrome prediction, respectively. Conclusion: It seems that visceral adiposity index is a reliable marker for the screening of cardiometabolic disorders in the women with PCOS.
Maryam Aalaa, Mohammad Reza Mohajeri-Tehrani, Ghobad Ramezani, Mohammad Reza Amini, Maryam Aboeerad, Mahnaz Sanjari,
Volume 19, Issue 1 (1-2020)
Abstract
Background: Peripheral neuropathy is one of the most common problems in diabetic patients. The increased risk of Diabetic Foot Ulceration (DFU) and amputation would be a complication of diabetic neuropathy. The aim of this study was to compare the DFU healing in different severity classification of neuropathy.
Methods: This is a retrospective study that was conducted over a two-year period from April 2016 to March 2018 according to the information of patients records with Diabetes Mellitus (DM) referred to clinic of diabetes and metabolic disorders of Endocrinology and Metabolism Research Institute of Tehran University of Medical Sciences. Wound healing criteria including area, depth and healing duration were studied. Accordingly, changes in the area and depth of wounds were evaluated and reported during the first, third and sixth months after baseline. Data were analyzed using descriptive and inferential statistics using SPSS software version 16.
Results: The results of the study of patients with neuropathic ulcer showed that males and age group of 56 to 65 years had the highest frequencies. In addition, most of these patients suffered from type 2 DM (79%). The rate of wound healing, which was measured by area and depth of wound in three time periods, differed in different severity classification of neuropathy; at mild level of neuropathy the area and depth of wound decreased faster but in severe neuropathy, duration of wound healing in both mentioned criteria has increased. Regarding to the increase in the duration of DM, the healing time increased too. However the rate of wound healing decreased with increased age (p-value = 0.001).
Conclusion: Evidence suggests that early identification of neuropathy can reduce the incidence of DFU and amputation. Due to the slow healing of the size and depth of the wound in diabetic patients with severe neuropathy, it is necessary to prevent DFU by conducting preventive care and educational interventions.
Samira Behboudi-Gandevani, Mojgan Modoodi, Razieh Bidhendi Yarandi, Mina Amiri, Amir Abbas Momenan, Fereidoun Azizi, Fahimeh Ramezani Tehrani,
Volume 19, Issue 1 (1-2020)
Abstract
Background: Although a positive association between type 2 diabetes and breast cancer has been reported, an association with gestational diabetes mellitus (GDM) is less clear. This study aimed to assess the relationship between the history of GDM and the incidence of BC a long term population based study.
Methods: To conduct this research, 4076 women aged 20-50 years who participated in the first phase of Tehran-Lipid-and-Glucose-Study, who had at-least one pregnancy were included. Each participants were asked about the history of GDM every 3 years. They was evaluated about the occurrence of breast cancer (BC). Cox-survival analysis was used to measure the Hazard-ratio (HR) for both groups with and without history of GDM
Results: The study population included 886 women with prior GDM and 3,909 women without history of GDM. The median duration of follow-up among women with and without the history of GDM were 12.12 and 11.62 years, respectively. The incidence of BC was 0.64 per 1,000 year-olds with confidence=interval of 95% (0.44-0.91). Among them, 4 cases were reported in women with GDM and 26 cases in women without GDM. (Incidence of 0.36 per 1000 person-years with confidence=interval 95% (0.11-0.99) in women with prior GDM and 0.73 per 1,000 person-years with confidence=interval 95% (0.49-1.1) in women without a history of GDM.
Conclusion: Our study showed that the history of GDM is not an independent risk factor for breast cancer.
Aboozar Ramezani, Leila Shahmoradi, Fereydoon Azadeh, Fatemeh Sheikhshoaei, Rasha Atlasi, Nazli Namazi, Bagher Larijani,
Volume 20, Issue 1 (25th Anniversary of the Foundation, Special Issue 2021)
Abstract
Background: A key aspect of Scientific collaboration increases scientific productivity. This study aimed to draw up a scientific collaboration network of the Endocrinology and Metabolism Research Institute (EMRI) at Tehran University of Medical Sciences.
Methods: A Descriptive Cross-Sectional Study was conducted by the Scientometrics method. Data collection from the Scopus and Web of Science Core collection databases between 2002 until 30 October 2020. MS-Excel, HistCite, VOSviewer, and ScientoPy were used for descriptive statistics and data analysis.
Results: A total of 4190 records with the affiliation of the EMRI are indexed in two international databases. All of the records received a sum of 89480 citations. The EMRI Researchers were published in 1118 journals. The annual growth rate of publication and citation of the scientific output of the EMRI was 20.3% and 22.7%, respectively. A total of 17662 authors from 186 countries participated in the publication. The co-authorship pattern shows. The next section of the Study was classified and visualized based on authorship (institutes and country of affiliation), keywords (co-occurrence and trend).
Conclusion: Overall, these results indicate that the pattern of collaborations in the authorships' articles increases the flow of knowledge among the institute's researchers as a result of international collaborations, interaction with leading countries, and interdisciplinary collaborations. To develop a full picture of co-authorship, additional studies will need a comprehensive picture of network cooperation to analyze the situation with other social network analysis indicators.
Sohila Mardani, Sayed Abbas Binias, Sajjad Ramezani,
Volume 22, Issue 2 (7-2022)
Abstract
Background: Irisin is a myokine that is released from FNDC5 membrane protein and has positive effects on carbohydrate metabolism. The aim of this study was to evaluate the effect of 8 weeks of aerobic exercise on irisin levels and insulin resistance in middle-aged women with type 2 diabetes.
Methods In this quasi-experimental study, 24 women with type 2 diabetes were purposefully selected and randomly divided into two groups of aerobic exercise (n = 12) and control (n = 12). The training group performed aerobic exercises for 8 minutes (3 sessions per week) for 50 minutes with an intensity of 45-85% of the maximum heart rate on the treadmill. The control group did not engage in any physical activity during exercise. Blood samples were collected 24 hours before and 48 hours after the last training session and the serum was used to measure the levels of irzin, insulin resistance index (HOMA-IR), fasting glucose and insulin. Correlated t-test and independent t-test were used to examine intra-group changes and differences between groups. Data analysis was performed using SPSS software (version 22) at a significant level (P≥0.05).
Results: Intragroup changes showed that 8 weeks of aerobic exercise increased serum levels of irizin (P = 0.000), significantly decreased insulin resistance index (HOMA-IR) (P = 0.000), fasting glucose and insulin ratio (P = 0.001) ratio He became diabetic in the control group. Also, in comparison between groups, aerobic exercise caused a significant increase in levels of irizin (P = 0.001) and a decrease in insulin resistance index (HOMA-IR), fasting glucose (P = 0.001) and insulin (P = 0.001) compared to the control group. He became diabetic.
Conclusion: Aerobic exercise, through its beneficial effect on increasing irisin levels and decreasing insulin resistance index, is an effective factor in improving glucose metabolism in type 2 diabetic patients.
Sajjad Ramezani, Amaneh Porrahim Ghouroghchi, Mohsen Yaghobi, Roghayeh Afroundeh, Mina Rasouli,
Volume 23, Issue 2 (5-2023)
Abstract
Background: During recent decades, physical activity has become a key auxiliary tool in controlling many diseases, including diabetes. The aim of this study was to investigate the effect of 8 weeks of resistance training on the plasma levels of preptin and endothelin 1 in men with type 2 diabetes.
Methods: The current research is semi-experimental. The statistical sample of this study consisted of 38 men with type 2 diabetes, who were randomly divided into two groups of 19 experimental and control. Subjects in the experimental group performed 8 weeks of resistance training three sessions a week with moderate intensity. 24 hours before and after 8 weeks of training, plasma levels of preptin, endothelin 1, and indicators related to type 2 diabetes were measured by the ELISA method. Correlated t-tests and independent t-tests were used to examine intra-group changes. SPSS software was used to analyze the data (P≥ 0.05).
Results: Correlated t results showed that plasma levels of preptin and insulin resistance index (P= 0.001) as well as plasma endothelin 1 (P= 0.001) decreased significantly in the post-test compared to the pre-test of the experimental group. has been found Also, the independent t-test results showed that the plasma levels of preptin, insulin resistance index (P= 0.001) and endothelin 1 (P= 0.002) were significantly lower in the post-test of the experimental group compared to the control.
Conclusion: According to the obtained results, it seems that doing resistance exercises improves glucose sensitivity by reducing preptin and reducing the possibility of blood pressure by reducing endothelin 1 in preople with type 2 diabetes.
Sajjad Ramezani, Marefat Siahkouhian,
Volume 24, Issue 2 (6-2024)
Abstract
Background: This review aims to investigate and analyze recent studies related to the effects of various exercise training on adipokines secreted from adipose tissue in patients with type 2 diabetes.
Methods: Search in Persian and Latin databases PubMed, ScienceDirect, Google Scholar, Magiran, and SID with the keywords aerobic exercise, resistance training, High-intensity interval training, diabetes, Adipokine, Leptin, Adiponectin, and Resistin, resistance training, intense interval training, aerobic exercise, combined exercise, adipokine, leptin, adiponectin and resistin were performed to retrieve articles published in the period from 2010 to 2023.
Results: The results obtained from the study showed that aerobic exercise with moderate intensity (60 to 80%) reduces the leptin levels of diabetic patients, however, the effect of combined exercises (aerobic and resistance) is much greater than other types of exercises. In addition, aerobic exercises with moderate intensity (50 to 70%) lead to an increase in adiponectin levels in diabetic patients, however, high-intensity interval training (HIIT) had a greater effect in increasing adiponectin levels than other exercises. Also, studies showed that all three types of activities, aerobic exercise (50-70% intensity), intense intermittent exercise, and resistance exercise (30-70% 1RM) have the same effects in reducing the resistance levels of diabetic patients.
Conclusion: Aerobic exercises with medium and high intensity and especially combined exercises (aerobic and resistance) while improving adipokines, decreasing leptin and resistin levels, and also increasing adiponectin in diabetic patients.
