Monir Jadidoleslami, Mehdi Abbas Nejad, Mohammad Reza Shahraki,
Volume 6, Issue 2 (18 2006)
Abstract
Background: Aloe vera is a herbal plant being used as an anti-inflammatory agent, burning recovery as well as immune system boosting agent. The aim of this study was to evaluate the effects of Aloe vera on blood glucose , lipids and lipoproteins in streptozotocin-induced diabetic male rats.
Methods: This study was carried out on 56 male rats, weighing 150-200 gr. Animals are divided into 7 groups (one control and six test groups). Diabetes were induced in test groups via streptozocin (65mg/ kg-IP). After a week, blood samples analyses for FBS. All diabetic groups, except the control one, were taken 100,200,300,400 mg/kg Aloe vera extract and 5mg/kg glibenclamid by gavages for a period of 4 weeks, respectively. After this period fasting blood samples were collected from all groups.
Results:The results showed that the FBS decreased in groups that received 400mg/kg and glibenclamid (respectively,162/62±23.12and193.37±26.51). In addition, 3-6 groups showed decrease TG and Cholesterol level in comparison with those of control groups. In all groups which received Aloe vera and glibenclamid, LDL level were significantly decreased in comparison with control groups but HDL level had no change.
Conclusion: The results of this research indicate that Aloe vera aqueous extract lead to decreased Blood glucose, Cholesterol, LDL and TG levels. Further studies is suggested for exact mechanism of Aloe vera in diabetic rats.
Roohangiz Alirezaei Shahraki, Ahmad Aliakbari Kamrani, Robab Sahaf, Yahola Abolfathi Momtaz, Narjes Khosravi Samani,
Volume 17, Issue 5 (7-2018)
Abstract
Background: Diabetes is a chronic disease that is increasing in the world that has a different outbreak in different societies. 90% to 95% of all types of diabetes include type 2 diabetes. This disease is spreading due to the Industrial life and urbanization .The Nationwide Program for Prevention and Control of Diabetes is already under way for controlling the disease and its side-effects. This study is intended to probe into the effects of the program in the country.
Methods: This study used a cross-sectional pre- and post-test design involving 100 elderly patients newly introduced to be suffering from diabetes who were selected by convenience sampling in Isfahan. The data collection methods were a questionnaire on demography and health, and another one on patients’ levels of fasting blood sugar (FBS) and hemoglobin glycosides (HbA1c(The data was gathered before and three months after the patients’ entrance into the program.
Results: The mean and standard deviation of the fasting blood sugar before the program were 172.73 and 71.68 and after the program 143.02 and 51.19, respectively (P<.001; t=5.30). And finally, glycated hemoglobin mean and standard deviation before the program were 8.24 and 1.9 and after the program 7.44 and 1.66, respectively (P<.001; t=4.79).
Conclusion: The results indicate the importance of the program for the prevention and control of the elderly patients’ diabetes by controlling their fasting blood sugar and glycated hemoglobin.It is recommended that this program be implemented in all health centers of the country.
