Showing 4 results for Shojaei
Mohammad Ali Besharat, Forough Shojaei, Alireza Kiamanesh, Hamid Amiri,
Volume 14, Issue 2 (1-2015)
Abstract
Background: The role of obesity and overweightness in emerging and enduring of serious medical and psychological disorders on one hand and the effect of psychological factors in obesity on the other hand, has made the surveys about psychological role in obesity of great importance. The aim of the present study was to compare the attachment styles and parenting styles of obese and non-obese adults. Methods: 144 individuals (72 obese patients: 48 females and 24 males) and (72 non-obese: 48 females and 24 males) participated in this study. Participants were asked to complete the Adult Attachment Inventory (AAI) and the Parental Authority Questionnaire (PAQ). Results: There was a negative relationship between secure attachment and Body Mass Index (BMI) of the obese patients, but no statistically significant relationship between insecure attachment styles (avoidant and ambivalent) was found. There was also a statistically significant relationship between the mean scores of secure and ambivalent attachment styles with BMI. Regarding the parenting styles and BMI, there was a statistically significant relationship between authoritative parenting style of the father and BMI, but no relation between authoritarian and permissive parenting styles was confirmed. Conclusion: Regarding the role of attachment styles and parenting styles of obese and non-obese adults, we can improve the physical and psychological public health of patients by changing the prevention and treatment protocols for the patients.
Masoumeh Shojaei Barjouei, Somayeh Norouzi, Parsa Bernoos, Kimia Mokhtari, Azizeh Asadzadeh,
Volume 22, Issue 3 (9-2022)
Abstract
Background: Diabetes mellitus is a group of metabolic disorders that are associated with elevated blood glucose levels due to impaired insulin secretion, insulin function, or both. alpha-glucosidase is a key enzyme in hydrolyzing carbohydrates and raising blood sugar levels. This study aimed to investigate the bioinformatics of inhibition of the alpha-glucosidase enzyme by the main constituents of Salvia officinalis.
Methods: This research was done by descriptive-analytical method. To study how the compounds interact and the amount of binding energy in the active site of the enzyme, the three-dimensional structure of the compounds and proteins were obtained from PubChem and PDB database, respectively. After energy optimization by Hyperchem software, docking studies were performed by AutoDock 4.2 software and the Swiss ADME server was used to obtain Lipinski parameters and physical and chemical properties of the compounds.
Results: The studied compounds were similar to the two positive control compounds, Voglibose and miglitol, in terms of binding energy and how they interact. The best docking results are related to the camphor . In fact, this compound with the most negative binding energy level (-3.95 Kcal / mol) has a greater tendency to bind to key amino acids in the active site of the alpha glucosidase enzyme.
Conclusion: Due to the appropriate interactions of Salvia officinalis.compounds with enzymes, after confirming the results in vitro and in vivo, this plant can be used as a suitable drug candidate in the treatment of diabetes.
Fatemeh Kazeminasab, Mohadeseh Shojaei, Mousa Khalafi,
Volume 22, Issue 6 (3-2023)
Abstract
Background: Non-alcoholic fatty liver disease (NAFLD) is a pathological syndrome associated with increased serum levels of liver enzymes. The purpose of this study was to investigate the impact of exercise training on liver enzymes (ALT, AST, and GGT) and liver fat content in adults with NAFLD.
Methods: The PubMed, Web of Science, SID, Magiran, and Google scholar databases were searched until February 2022 for English and Persian articles. Meta-analyses were performed to compare the impact of exercise training on liver function in patients with fatty liver. SMD and 95% confidence interval (95% CI) were calculated using effect models. Also, the I2 test was used to determine heterogeneity, and the Funnel plot and Egger tests at a significant level of 0.1 were used to determine publication bias.
Results: The results of meta-analysis of 36 studies with 1602 patient with NAFLD, showed that exercise training caused a significant decrease in ALT enzyme [SMD=-0.73, (95% CI: -0.51 to -0.95), p=0.001], AST enzyme [SMD=-0.61, (95% CI: -0.39 to -0.83), p=0.001], GTT enzyme [SMD=-0.66, (95% CI: -0.18 to -1.14), p =0.007], and intrahepatic fat [SMD=-0.58, (95% CI: -0.78 to -0.38), p=0.001].
Conclusion: The findings of the present meta-analysis show the important role of exercise training (aerobic, resistance, and combined training) in improving liver function. So, all three types of aerobic, resistance, and combined exercise are suggested as a non-drug approach to reduce liver enzymes and intrahepatic fat for adults with NAFLD.
Farzaneh Shojaei, Zohreh Latifi, Sheida Jabalameli, Mansour Siavash,
Volume 24, Issue 4 (10-2024)
Abstract
Background: Type 2 diabetes is a common disease, which is associated with psychological problems. This study aimed to compare the effectiveness of self-healing on difficulties in emotion regulation and blood sugar index in patients with type 2 diabetes.
Methods: This research was semi-experimental (pre-test, post-test, follow-up with control group). The statistical population consisted of 300 people with type 2 diabetes who visited Sedighe Tahereh Clinic in Isfahan in 2021. Of these, 40 people were selected through purposive sampling and were assigned randomly in the experimental and control groups. Data collection tool was Gratz and Romer’s (2004) Difficulties in Emotion Regulation Scale (DERS) and laboratory equipment to measure blood sugar index. the experimental groups underwent 12 sessions of self-healing therapy and the control group did not receive any treatment. Analysis of variance with repeated measures and Bonferroni’s post hoc test were used to analyze the data. SPSS version 24 was used to analyze the data
Results: The results showed that self-healing has an effect on difficulties in emotion regulation and blood sugar index (P<0.05) and this result is continuous (P<0.05).
Conclusions: According to the results, it can be said that self-healing is effective in manegment of blood sugar of people with type 2 diabetes.
