Showing 5 results for Soveid
Mahmood Soveid, Masood Kaviani, Mohammad Behgam, Gholamhosein Omrani,
Volume 2, Issue 2 (17 2003)
Abstract
Background: A controversy exists on the prevalence of hearing impairment in diabetic patients. Previous studies have reported figures ranging from 0 to 93%.
Methods: 80 diabetic patients (mean age: 49.0816 range: 16-65 years) were evaluated with regards to their hearing thresholds, using pure tone and speech audiometry. The results were compared with 78 healthy controls.
None of the patients or controls reported histories on exposures that might affect their hearing power.
Results: For all frequencies, lower hearing thresholds were registered in diabetic patients (on average 5.741.8 dB) compared to the controls. In sum, 53.7% of diabetics showed hearing thresholds lower than controls. Diabetics had poorer speech discrimination function but equal speech reception as compared to the controls.
Age seemed to influence the mode of hearing impairment in the diabetic patients. To say, high frequencies disturbances were more commonly affected in older diabetics the reverse was true for the younger ones.
Genders, duration of diabetes and positive family history for diabetes were not related to the degree of hearing impairment. Patients with retinopathy had poorer hearing threshold.
Conclusion: Hearing loss seems to be a frequent feature of diabetes mellitus.
Mahmood Soveid, Mohammad Reza Ghavanini, Elaheh Shirdel, Gholamhossein Omrani,
Volume 3, Issue 1 (16 2004)
Abstract
Neuropathy is a common complication of diabetes mellitus. Meticulous neurological examination and electrodiagnosis are valuable tools in early diagnosis of neuropathy and prevention of its sequels.
Methods: A hundred and three randomly selected diabetic patients were recruited from the endocrine clinic. Mean age of patients was 52.6 ±14 years. 29.4% had type 1 and 70.6% had type 2 diabetes.
Medical history was taken from patients and neurological examination was done. Electroneurographic examination included nerve conduction velocity, action potential amplitude, distal latency and H reflex measurements.
Results: Neuropathy was found in 79.4% of patients. The prevalence of neuropathy had a direct relation with duration of the disease. The most common complaints were tingling and numbness of extremities (72%) and burning sensation of the feet (36%). The most common physical findings were abnormal ankle jerk (92%), and decreased vibration perception (76%) in feet. Abnormal H reflex
(92.5%) and decreased amplitude of action potentials (79%) were the most common electroneurographic findings. There was a strong correlation between clinical and electroneurographic findings.
Conclusion: Neuropathy was quite common in diabetic patients. Neurologic examination is, therefore, recommended to prevent unnecessary workups and prevent complications.
Gholam Hossein Ranjbar Omrani, Mahmood Soveid, Hassan Rajaii, Abdo Assamd Sadegholvaad,
Volume 3, Issue 2 (16 2004)
Abstract
Background: Chronic complications of diabetes causes substantial mortality and morbidity. The incidence and rate of progression of these complications depends on ethnic factors. The aim of this study was to investigate the incidence of late complications of diabetes and its relation to blood glucose control in a group of diabetic patients from South of Iran.
Methods: In this retrospective study, medical records of all diabetic patients who were followed regularly during a 12 year period at outpatient clinics of Shiraz University of Medical Sciences were investigated. Information regarding age, sex, type of diabetes, duration of disease , mean fasting and postprandial blood sugar, complications (eye, kidneys, peripheral nerves, foot, cardiovascular, cerebrovascular), and timing of complications with regard to duration of disease were collected.
Results: The study population included 392 patients (205 males and 186 females), 300 patients had type 2 and 92 had type 1 diabetes. The mean age at diagnosis was 20.412.8 years for type 1 and 47.510.4 years for type 2 patients. 95% of patients developed at least one chronic complication during the follow-up period. The incidence rates of eye , renal, and peripheral nerve complications were 51.5, 44.7, and 68.8 percent respectively. Diabetic foot problems occurred in 16.8 percent of cases and it led to amputation in 8.4 percent (33 cases) of patients. The incidence rates of cardiovascular and cerebrovascular complications were 49.7 and 15.3 percent respectively. The development of eye, renal, and peripheral nerve complications was related to blood sugar control.
Conclusion: Our diabetic patients developed chronic complications early and at a higher than expected rates. Future studies and more emphasis on prevention methods are recommended.
Mahmood Soveid, Ali Reza Serati, Gholam Hossein Ranjbar Omrani,
Volume 3, Issue 2 (16 2004)
Abstract
Background: Previous in vitro and animal studies have supported a role for growth hormone in development of diabetic nephropathy. The purpose of this study was to investigate the relation between basal and stimulated growth hormone and proteinuria in type 2 diabetic patients.
Methods: 21 type 2 diabetic patients with macroalbuminuria were selected. Fasting insulin, basal and levodopa stimulated growth hormone levels were measured. The control group consisted of 21 type 2 diabetic patients with 24 hr urine protein of less than 50 mg. The two groups were matched according to sex, age, duration of diabetes, body mass index, creatinine clearance, fasting blood sugar, glycosylated hemoglobin, and blood pressure.
Results: The patients with macroalbuminuria had higher basal growth hormone (3.1 2.6 vs 1.25 0.7 ng/ml, P = 0.024). Stimulated growth hormone and fasting insulin levels were not significantly different.
Conclusion: There is direct relation between basal growth hormone and development of diabetic nephropathy and this relation suggests a role for growth hormone in human diabetic nephropathy.
Mohammad Hossein Dabbaghmanesh, Mohammad Reza Kalantarhormozi, Mahmood Soveid, Abdosamad Sadeghalvad, Gholamhossein Ranjbar Omrani,
Volume 7, Issue 2 (17 2007)
Abstract
Background: The relationship between diabetes and serum insulin and Zinc (Zn) levels is complex with no clear cause and effect relationships. Since Zn plays a clear role in the synthesis, storage and secretion of insulin as well as conformational integrity of insulin in the hexametric form, the decreased Zn, which affects the ability of the islet cell to produce and secrete insulin, might then compound the problem, particularly in type 2 diabetes. The aim of this study was to determine the changes of plasma Zn in patients with type 2 diabetes mellitus and healthy control in Shiraz city.
Methods: As a case-control study, we determined the serum Zn levels by atomic absorption spectrophotometer, blood HbA1c levels with columnar chromatographic method and Glucose, by enzymatic colorimetric method in auto analyzer. Data are reported as the Mean±SD and P<0.05 was considered as statistically significant
Results: Results of this study revealed that levels of Zn in serum of diabetic patients is lower than in the healthy control in Shiraz city (P<0.05).
Conclusion: With respect to the result of this study, dietary educations about consuming enriched Zn foods such as sea foods and corn in diabetic patients is necessitated.
