Showing 4 results for Zafarmand
Omid Zafarmand, Fatemeh Kazeminasab,
Volume 25, Issue 1 (4-2025)
Abstract
Background: Physical activity and green tea are one of the recommended ways to control obesity and its complications such as cardiovascular diseases, diabetes and liver inflammation. The aim of this study was to evaluate the combined effect of exercise training and green tea on lipid profile in adults with overweight and obesity.
Methods: A systematic search of English and Persian articles published in PubMed, Web of Science, Scopus, SID, Civilica, and Magiran databases was conducted until June 2024.
Results: A total of 14 studies with 390 adults with overweight and obesity, of which 198 subjects were in the combined exercise and green tea group with an average age of 34 years old and BMI with an average of 30 kg.m2, of which 192 subjects in the control group with an average age of 34 years old and BMI with an average of 31 kg.m2 entered the present meta-analysis. The results showed that the combination of exercise training and green tea caused a significant decrease in TC [WMD=-22.923 mg/dL, P=0.001], TG [WMD=-9.946 mg/dL, P=0.001], LDL [WMD=-11.675 mg/dL, P=0.001] and significant increase in HDL [WMD=8.888 mg/dL, P=0.017] in adults with overweight and obesity, compared to the control group.
Conclusion: The results of this meta-analysis showed that the combination of exercise training and green tea in overweight and obese adults decreases TC, TG, LDL and increases HDL. Therefore, exercise and green tea can be suggested to to adults with overweight and obesity as a non-medicinal and practical solution to improve lipid profile.
Abbas Saremi, Omid Zafarmand,
Volume 25, Issue 2 (7-2025)
Abstract
Background: Irisine is a new myokine that is released from the membrane protein fndc5 and has positive effects on metabolism. The aim of the present study was to investigate the effect of high-intensity interval training on plasma irisin levels and glycemic indices in obese and type 2 diabetic people.
Methods: A systematic search of published English and Persian articles was conducted from PubMed, Web of Science, Scopus, SID, and Magiran databases up to 20 November 2024. The mean difference and 95% confidence interval (CI) were calculated using a random-effects model. Heterogeneity was assessed using the (I2) test and publication bias was assessed using visual analysis of funnel plots and Egger's test.
Results: A total of 11 studies and 264 obese and type 2 diabetic subjects were included in the present meta-analysis. The results showed that high-intensity interval training significantly increased irisin [WMD = 1.448 ng/ml (2.280 to 0.616), P= 0.001], significantly decreased glucose [WMD = -12.127 mg/dl (-24.180 to -0.074), P= 0.049] and insulin resistance [WMD= -1.275 (-0.567 to -1.983), P= 0.001] compared to the control group in obese and type 2 diabetic subjects. While insulin [WMD= -0.249Iu/ml (3.402 to -3.901), P= 0.894] was not significantly reduced.
Conclusion: Overall, the findings of the present meta-analysis indicate that high-intensity interval training plays an effective role in irisin, glucose, insulin, and insulin resistance to high-intensity interval training. High-intensity interval training increases irisin, decreases glucose, insulin, and insulin resistance in obese and diabetic individuals. Lifestyle modification and exercise training are preferred treatment strategy in obese and type 2 diabetic people.
Omid Zafarmand, Rahman Soori,
Volume 25, Issue 4 (9-2025)
Abstract
Background: Exercise training represents an effective approach that contributes substantially to lowering chemerin and vaspin levels, enhancing body composition, and preventing complications related to overweight and obesity. In this context, the present study sought to examine the effects of exercise training on chemerin, vaspin, and body composition in individuals with type 2 diabetes.
Methods: A systematic review and meta-analysis was conducted to evaluate the effects of exercise interventions on various outcomes in patients with type 2 diabetes. A comprehensive search for English and Persian articles published up to )January 4, 2025( was performed across the following databases: PubMed, Web of Science, Scopus, Google Scholar, IranDoc, Magiran, Noormags, and SID (Scientific Information Database). Fifteen studies, including 19 exercise interventions and 440 participants with type 2 diabetes, were included. Data were analyzed using a random-effects model, and the mean differences with 95% confidence intervals (CI) were calculated. Heterogeneity was assessed using the I² statistic, and publication bias was evaluated through visual inspection of funnel plots and Egger’s test.
Results: A total of 15 studies (with 19 exercise interventions) involving 440 participants with type 2 diabetes were included in the meta-analysis. The results indicated that exercise interventions led to non-significant changes in c-Merlin [SMD= −0.967, 95% CI: −2.453 to 0.518, P= 0.202], body mass index (BMI) [SMD= −0.228, 95% CI: −0.470 to 0.013, P= 0.064], waist-to-hip ratio (WHR) [SMD= −0.038, 95% CI: −0.773 to 0.007, P= 0.054], and body fat percentage [SMD= 0.080, 95% CI: −0.524 to 0.685, P= 0.795] compared with the control group in individuals with type 2 diabetes.
Conclusion: The results of the present study demonstrated that exercise training significantly reduces vaspin levels in patients with type 2 diabetes, while it has no significant effect on chemerin, body composition, or body composition indices (including body mass index, body fat percentage, and waist-to-hip ratio). It appears that physical exercise may play an effective role in improving the metabolic status of patients with type 2 diabetes through the modulation of vaspin levels.
Khadijeh Molaei, Mehdi Mogharnasi, Omid Zafarmand,
Volume 26, Issue 1 (4-2026)
Abstract
Background: Obesity is one of the causes of diabetes. On the other hand, exercise along with cinnamon supplementation has been recommended as an important approach for controlling and preventing obesity and its related complications, such as diabetes and insulin resistance. Therefore, the aim of the present study is to investigate the combined effect of exercise training and cinnamon supplementation on glycemic indices in individuals with obesity and type 2 diabetes.
Methods: A systematic search of English and Persian articles published in PubMed, Web of Science, Scopus, Magiran, Google Scholar, NorMags, Irandoc, and SID databases was conducted up to January 2025. In data analysis, a random-effects model was used to calculate the weighted mean difference (WMD), standardized mean difference (SMD) and 95% confidence interval (CI). Also, heterogeneity of studies was assessed with the I² test.
Results: In total, 11 studies involving 230 participants with obesity and type 2 diabetes were meta-analyzed. The results indicated that the combination of exercise training and cinnamon supplementation significantly reduced glucose (WMD = -13.317 [95% CI: -19.599 to -7.034]; P = 0.001) and insulin resistance (WMD = -1.098 [95% CI: -1.577 to -0.618]; P = 0.001) compared to the control group in individuals with obesity and type 2 diabetes. However, insulin levels did not show a significant change (WMD = -2.123 [95% CI: -4.333 to 0.088]; P = 0.060).
Conclusion: The results of the present meta-analysis demonstrated that the combination of exercise training and cinnamon supplementation improves glucose and insulin resistance in individuals with obesity and type 2 diabetes. These beneficial effects are not accompanied by changes in insulin levels.
