Showing 67 results for Men
Alireza Safarzade, Khadije Esmailpour, Elahe Talebi-Garakani, Rozita Fathi,
Volume 13, Issue 3 (3-2014)
Abstract
Background: Adiponectin and omentin-1 are adipokines with insulin-sensitizing properties. The aim
of this study was to investigate the effect of resistance training on serum levels of adiponectin and
omentin-1 in Streptozotocin-induced diabetic rats.
Methods: Twenty four male Wister rats (12-14 weeks’ old) were randomly divided into three groups:
non-diabetic control, diabetic control, and diabetic training. The rats in diabetic training group were
subjected to a resistance training program (3 days/wk, for 4 wk) consisted of climbing a ladder
carrying a load suspended from the tail. Following four weeks resistance training serum glucose,
insulin, lipid profile, adiponectin, and omentin-1 concentrations were measured.
Results: Serum levels of omentin-1 and adiponectin were significantly lower in diabetic control group
compare with non-diabetic control group (P<0.001). After 4 weeks of resistance training serum
adiponectin levels was significantly higher in diabetic trained group compared with diabetic control
group (P= 0.028), but we did not find any significant difference in omentin-1 levels between two
diabetic groups. Morever, we did not find any significant difference in serum lipid profile among all
groups. Four weeks resistance training did not change serum glucose and insulin concentrations in
diabetic rats.
Conclusion: This study indicated that resistance training could increase serum adiponectin levels in
diabetic rats without significant changes in lipid profile, glucose, insulin, and omentin-1
concentrations. It seems low intensity and short term duration of resistance training had important
roles in failure of significant changes of omentin-1, glucose, and insulin concentrations.
Fariborz Bakhtiyari, Mahshid Foroughan, Hossein Fakhrzadeh, Neda Nazari, Baharak Najafi, Mahtab Alizadeh, Seyed Masoud Arzaghi, Farshad Sharifi, Shervan Shoaee, Qorbani Mostafa ,
Volume 13, Issue 6 (9-2014)
Abstract
Background: One of the common problems of the elderly, which increase of its prevalence with aging is the dementia and the cognitive impairment. We can help the involved patients to have a better quality of life with early diagnosis of the cognitive impairment. The aim of this study was an assessment of the validity and reliability of the Persian version of the abbreviated mental test (AMT) among the older people in a nursing home setting.
Methods: 176 eligible elderly people aged ≥ 60 years living in KahrizakCharity Foundation (KCF), were selected randomly based on medical record number. Demographic information and past medical history of the participants were collected. Geriatric depression scale 15 (GDS-15), global deterioration scale (GDS) forms and also the Persian version of the abbreviated mental test (AMT) were administered. The participants were assigned to two groups the normal and impaired cognitive groups, based on DSM-IV diagnostic criteria. The GDS cut-points were used for assessment of validity, sensitivity and specificity of the Persian version of AMT.
Results: The mean age of the participants was 77.30 (7.94) years. The Persian version of AMT had good discriminated validity in diagnosis of normal and impaired cognitive participants (7.35 ± 2.33 and 5.99 ± 2.29, P < 0.01 respectively) and at cut-point AMT< 8,(based on GDS cut-point) it had a sensitivity and specificity 92.15 % and 81.50% respectively. The sensitivity and specificity based on theism IVcriteriawere 64.9% and 64.0% at cut-off point equal to 7, respectively. The internal consistency of the Persian version of AMT was acceptable (Cronbach’salpha coefficient =0. 76). As well as the external reliability (intra-rater) of this instrument was good inter-class correlation coefficient (ICC) = 0.89)
Conclusion: The Persian version of the AMT has appropriate validity and reliability in Iranian older people.
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Volume 13, Issue 6 (9-2014)
Abstract
Background: Dementia is a common health problem in the elderly. Studies have shown that levels of pulse wave velocity (PWV) could predict cognitive impairment. The objective of this study was assessment of the relationship between arterial stiffness levels and cognitive status among the older people.
Methods: In this cross-sectional study, 60 individuals included 31 women and 29 men aged ≥ 60 years who were admitted to Khatam-Ol-Anbya hospital in Tehran and were eligible, were randomly selected according to admission code. Data such as demographic information, Global Deterioration Scale level, Geriatric Depression Scale -15 score, were collected by face to face interview. The arterial stiffness was measured using Sphygomocor system by calculation of carotid to femoral pulse wave velocity. Data analyzing was conducted using univariate and multivariable logestic regression models.
Result: The mean age of the participants was 72.62 (7.62) and it was significantly higher in cognitive impairment than those who had normal cognition [73.40(7.36) vs. 70.27(8.00) respectively, P = 0.05]. The average years of the schooling in individuals with normal cognitive status was higher than the other groups (P < 0.01). Average pulse wave velocity in the participants was 11.81(4.11) meters per second. The PWV was significantly increased with the exacerbation of the cognitive impairment (7.24 m/s in normal group vs. 15.52 m/s in the severe cognitive impaired group, P < 0.01).
Conclusion: The pulse wave velocity has an inverse relationship with cognitive status. It seems that arterial stiffness associates with lower levels of cognitive status independent to other cardiovascular risk factors.
Mohammad Asghari Jafarabadi, Seyede Momene Mohammadi, Akba Soltani,
Volume 14, Issue 2 (1-2015)
Abstract
In medical studies, measures are required to reveal the effect of exposures and interventions and also the precision of measurements. This paper aimed to introduce the measures of effect and agreement and inferences about them in these studies. Principles and method of calculating measures of effect and agreement and inference about them were presented for all types of medical studies taking into account the relevant considerations. To assess the effect of risk factors on outcomes in case-control and cohort studies, and to determine the relevant effect, the attributable risk and fraction in the exposed group and population were used along with their confidence intervals. Also the relative risk reduction, absolute risk reduction and number needed to treat were applied as the measures of effect of intervention in the interventional studies especially in trails. The sensitivity, specificity and related measures along with their confidence intervals were computed for diagnostic accuracy and screening studies. In addition it is needed to evaluate the precision of measurements using standard error of measurements, ICC, Altman and Bland’s limits of agreement and Lin’s concordance correlation coefficient for quantitative variables and using kappa and weighted kappa for nominal and ordinal variables. In each of these situations the results of research based examples were presented along with the methods of their calculations.To assess the measures of effect and agreement, the mentioned analyses are recommended considering the situation and purpose of the study.
Abass Bayat Asgari, Sahar Mossanejad, Mina Asgari, Abass Ramazani Farani, Javad Javaheri,
Volume 14, Issue 2 (1-2015)
Abstract
Background: Having high knowledge in patients is not sufficient for disease control and it is necessary to get more skills and capabilities that could be helping in confronting with diabetes associated stresses. This study is aim to assess the relationship between coping styles approaches with adherence to treatment in type 2 diabetic patients. Methods: In a cross sectional design 100 type 2 diabetic patients were selected by convenience route. Folkman and Lazaros as well as adherence to treatment questionnaires were filled by participants. Data was analyzed by SPSS software version 16, spearman correlation test and linear regression model were used for inferential statistics. Results: Problem and excitement oriented subscales were significant correlation. The correlation between problem oriented subscale and adherence was positive and significant (P<0.05) so that regression model showed as this subscale increase the adherence was increasing as well. The correlation between excitement oriented subscale and adherence was negative and significant (P<0.05) so that regression model showed as this subscale increase the adherence was decreasing. Conclusion: The results emphasized that there is significant correlation between copying styles and adherence to treatment in type 2 diabetic patients.
Mohammad Ali Besharat, Forough Shojaei, Alireza Kiamanesh, Hamid Amiri,
Volume 14, Issue 2 (1-2015)
Abstract
Background: The role of obesity and overweightness in emerging and enduring of serious medical and psychological disorders on one hand and the effect of psychological factors in obesity on the other hand, has made the surveys about psychological role in obesity of great importance. The aim of the present study was to compare the attachment styles and parenting styles of obese and non-obese adults. Methods: 144 individuals (72 obese patients: 48 females and 24 males) and (72 non-obese: 48 females and 24 males) participated in this study. Participants were asked to complete the Adult Attachment Inventory (AAI) and the Parental Authority Questionnaire (PAQ). Results: There was a negative relationship between secure attachment and Body Mass Index (BMI) of the obese patients, but no statistically significant relationship between insecure attachment styles (avoidant and ambivalent) was found. There was also a statistically significant relationship between the mean scores of secure and ambivalent attachment styles with BMI. Regarding the parenting styles and BMI, there was a statistically significant relationship between authoritative parenting style of the father and BMI, but no relation between authoritarian and permissive parenting styles was confirmed. Conclusion: Regarding the role of attachment styles and parenting styles of obese and non-obese adults, we can improve the physical and psychological public health of patients by changing the prevention and treatment protocols for the patients.
Maryam Bahadori , Leila Kohan, Nosaybeh Jafari ,
Volume 14, Issue 2 (1-2015)
Abstract
Background: obesity is the major health problems affecting communities worldwide and the prevalence is rapidly rising. Obesity as a lifestyle-related factor increases the risk of many diseases. Omentin is a new adipocytokine that is abundantly expressed in visceral fat tissue and its expression levels reversely correlated with obesity. The purpose of this study was to investigate the association between Val109Asp genetic polymorphism of Omentin gene and obesity risk in women. Methods: This case - control study was done on 260 women, including 186 women with BMI<30 as a control group and 74 women with BMI&ge30 with obesity. Omentin genotypes were determined by the use of polymerase chain reaction (PCR) followed by restriction fragment length polymorphism (RFLP). The data were analyzed using the computer software SPSS for windows version17. Results: Genotype frequencies of the Asp/Asp, Asp/Val and Val/Val in the control group were 65.6%, 31.7%, 2.7% and obese patients were 51.4%, 39.2%, 9.5%, respectively. Comparison of genotype frequencies in the two groups showed that women with Val/Val genotype in compare to Asp/Asp had greater risk for complications of obesity (OR: 4.5, 95%CI: 1.3-14.9, P: 0.01). Conclusion: There is significant association between Val109Asp polymorphism in omentin gene and obesity in Iranian women.
Hossein Farzalivand,
Volume 14, Issue 4 (5-2015)
Abstract
Background: One of the serious complications of type 1 diabetes is a sudden increase and drop in blood glucose levels causing risks of anesthesia and coma. Thus, an important step towards the optimal control of the disease is to use intelligent methods with low error rate and available information in order to predict and prevent such complications. In this paper, a combined Fuzzy SARSA algorithm was employed to design an expert system to predict fluctuations in blood glucose levels in patients with type 1 diabetes. The aim of this paper is to propose and implement a new algorithm based on reinforcement learning and fuzzy logic called FSA (Fuzzy SARSA Algorithm) to develop an expert system. Methods: The medical data used in this article were related to 3 Iranian female patients with type 1 diabetes. The data included parameters such as the type and dose of injected insulin and time interval between the hours of recorded blood glucose level and the one at the beginning of the period. A well-known reinforcement learning algorithm called SARSA was implemented with fuzzy logic. The Fuzzy SARSA algorithm was used in an expert system to predict fluctuations in blood glucose levels in patients with type 1 diabetes. Results: The results of the expert system with the proposed FSA algorithm for a learning factor included the parameters of blood glucose level at the beginning of the period (mg/dlit), short-acting injected insulin dose in to the body (unit), long-acting injected insulin dose (unit), stress level (unit), physical activity level (unit), used carbs (gr), and the interval between the beginning and end of the period (hour). They indicated that the factor managed to keep blood glucose levels at 85% in a normal range of 80 to 120, and it had 15% error. The error was observed in cases in which there was no proper exploratory factor for short-acting and long-acting injected insulin. Conclusion: According to the results, it was found that the proposed algorithm for intelligent system, with an approximate reduction of 15% in prediction error, can be used as a good model to predict fluctuations in blood glucose levels in patients with type 1 diabetes in comparison with other conventional methods including the ones based on reinforcement learning. In addition, other prediction methods based on artificial intelligence such as neural networks can be used to predict the results accurately.
Abodulaziz Aflakseir, Sare Raoofi, Javad Mollazadeh, Farhad Khormaei, Azam Farmani,
Volume 14, Issue 5 (7-2015)
Abstract
Background: Health locus of control is an important variable in diabetes. The aims of the present study were to investigate the role of health locus of control in predicting psychosocial adjustment to illness and compare psychosocial adjustment to illness and dimensions of health locus of control among male and female type 2 diabetic patients.
Methods: One hundred and eighteen patients were recruited via convenience sampling method from type 2 diabetic patients who were referred to the Shahid Motahari diabetes clinic in Shiraz. The participants filled Multidimensional Health Locus of Control (MHLC) and Psychosocial Adjustment to Illness Scale (PAIS).
Results: The results indicated that there were significant positive correlations between psychosocial adjustment to illness and internal health locus of control (r= .30, P &le .001) and God health locus of control (r= .18, P &le .05). Internal health locus of control (&beta= .28, P &le .01) significantly predicted psychosocial adjustment to illness. There were significant differences between male and female diabetic patients on the basis of chance health locus of control. Female patients got higher scores on chance health locus of control. Moreover, there were no significant differences between male and female diabetic patients on the basis of psychosocial adjustment to illness.
Conclusion: The findings highlighted that internal health locus of control and God health locus of control play significant role in psychosocial adjustment to illness. Therefore, it is recommended that psychologists and clinicians take the dimensions of health locus of control into considerations in the treatment of psychological problems of diabetic patients.
Alireza Safarzade, Fakhri Baradaran-Jam, Elahe Talebi-Garakani, Rozita Fathi,
Volume 14, Issue 5 (7-2015)
Abstract
Background: kallikrein 7 (KLK7), a serine protease with a chymotrypsin-like specificity, is able to cleave human insulin in the A- and B-chain. The aim of this study was to investigate the effects of aerobic exercise training on plasma KLK7 concentration and insulin resistance index (HOMA-IR) in normal and overweight sedentary women.
Methods: Twenty-eight sedentary women, aged 24-60 years, voluntary participated in this study and according to body mass index status divided into normal (n=15) and overweight (n=13) groups. All subjects completed an 8-week progressive aerobic exercise training program (running with 40- 80% Heart rate reserve). Metabolic and Anthropometric (body weight, BMI, body fat percentage) parameters in addition to plasma KLK7 concentrations were measured at baseline and end of training program.
Results: Body fat percentage significantly decreased (P<0.05) and maximum oxygen consumption increased (P<0.05) by this training program in both training groups. At baseline, plasma KLK7 concentration in overweight women was significantly higher compared with normal weight group (P<0.05). Plasma KLK7 concentrations significantly increased after 8-week aerobic exercise training only in normal weight group (P<0.05). Changes in plasma KLK7 concentrations were not correlated with changes in insulin concentration and insulin resistance index (P<0.05).
Conclusion: Aerobic exercise training could be an effective factor to increase plasma KLK7 concentration in sedentary women. These data do not support a role of plasma KLK7 in insulin resistance alterations.
Mehdi Sadeghian, Zatollah Asemi, Maryam Karamali, Parvane Saneei, Esmaillzadeh Ahmad ,
Volume 15, Issue 1 (1-2016)
Abstract
Background: This study was designed to assess the effects of calcium and vitamin D supplementation on the metabolic status of pregnant women with gestational diabetes mellitus (GDM).
Methods: This randomized placebo-controlled trial was performed at maternity clinics affiliated to Kashan University of Medical Sciences, Kashan, Iran. Participants were 56 women with GDM at 24–28 weeks gestation (18 to 40 years of age). Subjects were randomly assigned to receive calcium plus vitamin D supplements or placebo. All study participants were blinded to group assignment. Individuals in the calcium–vita- min D group (n = 28) received 1,000 mg calcium per day and a 50,000 U vitamin D3 pearl twice during the study (at study baseline and on day 21 of the intervention), and those in the placebo group (n = 28) received two placebos at the mentioned times. Fasting blood samples were taken at study baseline and after 6 weeks of intervention.
Results: The study was completed by 51 participants (calcium–vitamin D n = 25, placebo n =26). However, as the analysis was based on an intention-to-treat approach, all 56 women with GDM (28 in each group) were included in the final analysis. After the administration of calcium plus vitamin D supplements, we observed a significant reduction in fasting plasma glucose (p < 0.001), serum insulin levels (p = 0.02) and HOMA-IR (p = 0.001) and a significant increase in QUICKI (p = 0.003) compared with placebo. In addition, a significant reduction in serum LDL-cholesterol (P=0.02) and total cholesterol: HDL-cholesterol ratio (p = 0.003) and a significant elevation in HDL-cholesterol levels (p = 0.01) was seen after intervention in the calcium–vitamin D group compared with placebo. In addition, calcium plus vitamin D supplementation resulted in a significant increase in GSH (p =0.03) and prevented a rise in MDA levels (p = 0.03) compared with placebo.
Conclusion: Calcium plus vitamin D supplementation in women with GDM had beneficial effects on their metabolic profile.
Rezvane Galdavi, Mehdi Mogharnasi,
Volume 15, Issue 2 (1-2016)
Abstract
Background: Omentin-1 is recognized as new Adipokine that mostly is excreted from visceral fatty tissue. Circulating levels of Omentin-1 are inversely associated with obesity. The aim of the present study on two training methods of endurance and resistance on Omentin-1 levels of plasma and factors related to obesity and overweight in obese girls, respectively.
Methods: Thirty four obese and overweight girls (BMI>25) were chosen purposefully then they were categorized at random to three endurance group (n=12), resistance group (n=12) and control (n=10). A total of 8 weeks of endurance and resistance training and endurance training was 4 times a week with 65 to 80 percent of HRmax and intensity resistance training was 65-80% of 1RM. Phlebotomizing was done at various stages with similar conditions and plasma Omentin-1 levels by ELISA method was measured. Data were analyzed by Kolmogorov-Smirnov and related t tests for studying the changes within the ANOVA and LSD post Hoc test for comparison between groups at the significance level of p<0.05.
Results: The results showed a significant increase Omentin-1 in both the experimental group (p endurance =0.001, p resistance =0.004) and reduce factors associated with obesity such as weight (p endurance =0.003, p resistance =0.005), fat mass body (p endurance =0.001, p resistance =0.001), BMI (p endurance =0.002, p resistance =0.004) and WHR (p endurance =0.011, p resistance =0.013) in both experimental groups after 8 weeks of training (p<0.05).
Conclusion: It can be stated that both endurance and resistance practices after 8 weeks of training, to improve factors related to obesity, maximal oxygen uptake and increased plasma levels Omentin-1 was.
Mahin Nasrabadi, Mehdi Mogharnasi,
Volume 15, Issue 3 (2-2016)
Abstract
Background: Omentin-1 is known as adipokines that are secreted by visceral fat tissue. Omentin-1 levels are inversely associated with obesity. The aim of this research was investigation of the effect of Rhythmic aerobic exercise on serum concentration of Omentin-1 and same Anthropometric markers in obese women.
Methods: Thirty two obese women voluntarily selected with mean age 37± 8 years old and body mass index of 32.34±3.54 kg/m2 and randomly were divided into two groups of experimental (n=17) and control group (n=15). Subjects in the experimental group performed the exercise training with intensity 80-70% of maximum heart rate for 45-60 minutes per session, three times a week for 10 weeks. The control group did not participate in any exercise program. Omentin-1 serum levels, weight, body mass index and waist-to-hip ratio was calculated before and after exercise. Collected data were analyzed by using of Shapiro-Wilk, Leven, dependent t test and analysis of covariance (ANCOVA) with software SPSS version 21 in significant level of α<0.05 or α<0.001.
Results: 8 week aerobic exercise in the experimental group was associated with a significant increase in the omentin-1 levels (P=0.0001) and significant reduction of weights and body mass index (p= 0.0001) (P<0.05). Whereas there was no significant change in WHR levels (P>0.05). Reviews for between group indicated a significant increase in the amount of omentin-1 (P=0.009) and a significant reduction in weight values (P=0.0001) and BMI (P=0.001) in the experimental group compared with the control group (P<0.01).
Conclusion: It seems that rhythmic aerobic exercise is an important role in improving cardiovascular health and obesity-related disorders in obese women by increasing omentin-1 and reducing obesity-related factors.
Sayede Sahere Ghoreishi, Sajad Ahmadizad, Dariush Sheikhol-Eslami Vatani, Farhad Azari,
Volume 15, Issue 4 (5-2016)
Abstract
Background: The purpose of this study was the investigation effect of gender on plasma glucose, insulin and insulin resistance index in response to acute endurance activity and subsequent recovery periods in healthy individuals.
Methods: Eight females and seven males 20-30 years old (females 22.37±1.50 and men 23.42±1.27 years old, female weight 55.50±8.14 men and 79.85±15.16 kg, women height 160.12 ± 4.18 men and 179.71±6.57 cm) voluntarily participated in this study. Subjects performed two control activities during two consecutive weeks. The implementation of the sessions was randomly determined for each subject. Exercise program consisted of 45 min acute endurance at 75% of maximum heart rate on the treadmill and subsequently the subject was in a sitting position for one clock recovery. Four blood samples (6 ml) before and immediately after exercise, as well as 1 and 24 hours after the activity was collected. Two-way analysis of variance for data analysis was used.
Results: Regardless of gender, effects of activity and recovery on plasma insulin and insulin resistance index was significant (p <0.05) but not significant for glucose. Also when the data were corrected by changes in plasma volume, similar results were observed for insulin. Although changes of all factors (glucose, insulin, and insulin resistance) in response to activity session of acute exercise endurance was higher in men than in woman, gender has not significant effect on factors.
Conclusion: acute endurance activity and recovery induce change in insulin resistance index but these changes were not related to gender.
Nasimeh Sadat Razavi, Fereshteh Majlessi, Bahram Mohebbi, Azar Tol, Kamal Azam,
Volume 16, Issue 3 (3-2017)
Abstract
Background: Patient’s adherence to treatment regimen can predict treatment plan and decrease intensity and symptoms of sickness. This study aimed at determining the effect of educational intervention based on AIM (Ability, Information, Motivation) model on improving adherence of patients with type 2 diabetes.
Methods: This semi experimental interventional study was performed on 180 patients with type 2 diabetes as intervention and control groups. The patients selected using simple random sampling. Study instrument was a questionnaire including demographics (14 items) and AIM model questionnaire (10 items about information, 9items about motivation, 6 items for ability). After baseline, educational intervention was performed in intervention group and post test conducted after six months for both groups. Collected data was analyzed with SPSS software version 23using Mann–Whitney U, Wilcoxon and chi-squared tests. The significant level was considered less than 0.05.
Results: There was no significant difference in demographics and AIM model constructs between two groups (p>0.05). After educational intervention, intervention group revealed a significant difference with control group in terms of information (P<0.001), motivation (P<0.001), ability (P<0.001) and level of HbA1C (P<0.001).
Conclusion: study results revealed AIM model based educational intervention has an important role on treatment adherence among type2 diabetic patients. With increasing patient information and belief regarding disease patient’s motivation will be improved.
Farshad Sharifi, Neda Nazari, Shervan Shoaee, Hassan Ahmadi, Marjan Asadollahi, Seyed Masoud Arzaghi, Mahtab Alizadeh Khoee, Hossein Fakhrzadeh,
Volume 16, Issue 4 (9-2017)
Abstract
Background: Although several tools for evaluating and screening of cognitive status have been introduced, most of them are not applicable in Iranian elderly population because of cultural differences and high illiteracy rate. This study is report of "Brief Cognitive Assessment Tool"(BCAT) was developed as a cognitive status-evaluating test and reported psychometric characteristics.
Methods: the BCAT tool includes memory assessment using three words recall test with a rating similar to Mini-Cog and the functional status including "ability to dress", "ability to use the phone," " ability to manage own medications", among both two sexes and financial management capabilities in men and ability to prepare food in women. Functional rating is different in educated and non-educated people. Diagnosis of dementia is considered, when memory impairment is accompanied by the dysfunction. Eighty-six residents of a nursing home (41 men and 45 women) among who had inclusion and no had exclusion criteria also consent to participate were randomly enrolled. Concurrent validity was shown as correlation coefficient between the BCAT categorization and score of mini meAntal state examination (MMSE). Criterion validity, sensitivity and specificity of BCAT were evaluated based on global deterioration scale (GDS). Reliability of two raters results within two weeks was indicated by Kappa coefficient.
Results: The sensitivity and specificity and accuracy rate of the BCAT based the GDS was 88.6%, 82.6%, and 84.9%, respectively. The correlation between the MMSE score and results of the BCAT classifying was significant. The Kappa coefficient between the results of two raters was 81.1%.
Conclusion: It seems that the BCAT has good psychometric properties to recognize cognitive impairment among Iranian older adults.
Shahab Alizadeh, Khadijeh Mirzaei, Seyed Ali Keshavarz,
Volume 16, Issue 6 (10-2017)
Abstract
Background: The adipokines omentin-1, vaspin, and retinol binding protein-4 (RBP-4) are mediators of body composition and adipose tissue that contribute to metabolic changes caused by obesity. The aim of this study was to determine the association between serum levels of these adipokines with body composition indices and metabolic status in different phenotypes of body size.
Methods: In the present cross-sectional study, a total of 350 women, including 127 metabolically healthy (MH) subjects and 223 metabolically unhealthy (MUH) subjects participated. The subjects were considered as MH in the presence of at least 4 of the five following metabolic indices: TG ≤ 1.70 mmol/L, LDL-C≤ 2.60 mmol /L, TC≤ 5.20 mmol /L, HDL-C≥1.30, and HOMA-IR≤ 1.95; otherwise subjects were considered as MUH.
Results: The results showed that serum levels of omentin-1 have a significant positive association with MHS (OR = 1.04, p <0.0001). Even after controlling the confounding factors of age, sex and weight, this relationship was still significant. Plasma levels of vaspin and RBP-4 were not significantly related to MHS. Furthermore, there was a significant correlation between omentin-1 and body mass index (r = 0.31, p = 0.02) and body fat percentage (r = 0.32, P = 0.02) in MH subjects. In the healthy group, serum levels of RBP-4 were positively correlated with fat percentage (r = 0.68, p <0.0001) and body fat mass (r = 0.74, P <0.0001) and were negatively correlated with fat-free mass (r = -0.74, P <0.0001) and total body water (r = -0.76, P <0.0001). There was no statistically significant correlation between serum vaspin levels and body composition indices in both groups.
Conclusion: Serum levels of adipokines may be an appropriate predictor for metabolically healthy status. Further studies in this field can reveal possible mechanisms.
Maryam Hor, Golam Reza Manshaee,
Volume 16, Issue 6 (10-2017)
Abstract
Background: diabetes causes psychological problems besides physiologic ones for the people. Therefore the purpose of the present study was to determine the effectiveness of acceptance and commitment therapy on mental health of the patients with type 2 diabetes in the city of Isfahan.
Methods: the research method was semi-experimental and its design was pretest, post-test with control group and follow-up stage. The statistical population of included diabetic patients in Isfahan charity diabetes center in 2015. In order to do the study, 30 patients with type 2 diabetes were selected through improbable available and purposeful sampling method and put into experimental and control groups (15 in the experimental and 15 in the control group). The applied instruments were General health questionnaire (GHQ) and demographic questionnaire. After administering pretest, the experimental group received acceptance and commitment therapy during eight ninety-minute sessions in eight weeks while the control group didn’t have such intervention. After finishing therapeutic session, the people in two groups had the post test. After two months the follow-up test was administered. After data collection, the data analysis was conducted via COVARISNCE statistical analysis method through SPSS21 software.
Results: the results showed that there is a significant difference between experimental and control group between pretest and posttest scores (P<0.001). The results revealed that the effect of treatment was stable at the follow-up stage (P<0.001).
Conclusion: considering the significant effect of acceptance and commitment therapy on the mental health of the patients with type 2 diabetes, it is suggested to use this method to increase mental health of these patients.
Shima Keyvan, Noshiravan Khezri Moghadam, Asadollah Rajab,
Volume 17, Issue 2 (3-2018)
Abstract
Background: Diabetes is one of the most prevalent chronic illness that is closely associated with some psychological problems, particularly stress. In this case, psychological interventions can be useful. The aim of this study was to investigate effectiveness of Mindfulness Based Stress Reduction (MBSR) on psychosocial adjustment to illness in patient with type 2 diabetes.
Methods: In this study, semi-experimental method (pre-posttest) with control group was used. Population of the study included patients with type 2 diabetes that were member of Iranian Diabetes Society of Tehran. For sampling, 60 patients with type 2 diabetes were considered and then divided in two groups based on random sampling method. Psychosocial Adjustment to Illness Scale was used.
Results: ANCOVA showed that MBSR significantly effect on psychosocial adjustment to illness. Additionally, the results showed that MBSR significantly effect on attitude towards the disease and the social environment (P<0.05).
Conclusion: Findings revealed that MBSR can be effective on increasing psychosocial adjustment to illness in patients with type 2 diabetes. These findings have been inferred that patients with type 2 diabetes need to increase their psychosocial adjustment to illness.
Maryam Zangeneh, Nahid Mohamadi, Tahereh Kolahi, Ghodratolah Roshanei, Masood Khodaveisi, Arezoo Shayan,
Volume 17, Issue 3 (3-2018)
Abstract
Background: Gestational diabetes is one of the most common metabolic disorders during pregnancy. The purpose of this study was to determine Prevalence of Gestational Diabetes Mellitus in Pregnant Women Referred to Therapeutic and Health Centers in Hamadan Town.
Methods: This descriptive-sectional study was done in the year2014 on 620 pregnant women Referred to The health Centers in Hamadan Town. The necessary information was collected by means of a self-made
Questionnaire. The scientific validity of the questionnaire Comments 15 members of the faculty of nursing and midwifery. The necessary amendments were made. To determine the reliability question a pilot study on 10 patients was performed twice with an interval of 10 days and offer 0/91 reliability was confirmed Then the data was analyzed by using SPSS software, independent Fisher test, Chi-square and a=0.05 was taken as the significant level.
Results: 110 of the 620 cases studied (almost 17.1%) suffered from gestational diabetes mellitus and 38 cases of all (almost 6.1%) had overt diabetes. Mean age of the pregnant women was30.6±5 and BMI25.3±4.1 their mean number of pergment was 1.6±0.8. Increasing the hours of mother's work at home, body mass index, household size, number and history of abortion, number of pregnancies and delivery, and the history of diabetes in the family, the chance of having diabetes also significantly increases (P<0.05).
Conclusion: Regarding the great importance of gestational diabetes and its complications on the fetus, diabetes preventive practices demand special attention to pregnant women Regarding the trend of increasing the incidence of pregnant women to gestational diabetes mellitus and the effect of demographic and obstetric factors on its development, screening for women before admission for diabetes and healthy lifestyle education is recommended.
