Showing 87 results for Arya
Maryam Karkhaneh, Ehsaneh Taheri, Mostafa Qorbani, Mohamad Reza Mohajeri Tehrani, Saeed Hoseini,
Volume 14, Issue 4 (5-2015)
Abstract
Background: A unique subset of Individuals with normal body mass index (BMI= 18.5-24.9 kg/m2) and high body fat percentage (above 30% in women and 23% in men) that are termed as normal weight obese, are at increased risk for development of the metabolic syndrome and chronic diseases because the adipose mass and the excess of fat mass are an important source of proinflammatory cytokines. The aim of the present study was based on this hypothesis that women with high body fat percentage and normal body mass index are at increased risk for the metabolic syndrome in compared to healthy non obese women. Methods: This was as case-control study in which 40 obese women with normal weight (BMI= 18.5-24.9 kg/m2) and body fat percentage above 30% (FM> 30%) and 30 non-normal weight obese women (BMI= 18.5-24.9 kg/m2) and fat percentage less than 25% (FM <25%) who were matched for age (mean age = 28 years) recruited for this study. The components of metabolic syndrome including Anthropometric variables, blood pressure and fasting plasma concentrations of total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, glucose and insulin were measured. Results: The anthropometric measurements including waist and hip circumferences in NWO was higher than non-NWO (respectively 74.78±4.81 vs. 70.76±2.91 and 99.12±4.32 versus 93.16±2/91, Pvalue<0.001), while the waist-to-hip ratio did not differ between the two groups (p=0.448).Also no significant differences were observed in concentrations of total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, fasting plasma glucose, systolic and diastolic pressure between groups. Fasting serum insulin and insulin resistance was higher in NOW compared to non NWO (Pvalue<0.05) and insulin sensitivity in NWO was lower than non NWO (0.357 versus 0.374, pvalue = 0.043). Conclusion: Because of the higher serum insulin concentration and the lower insulin sensitivity, obese women with normal body mass index but high body fat percentage can be associated with a higher risk for metabolic dysregulation and metabolic syndrome compared to healthy women with the same body mass index and normal body fat percentage
Maryam Ahmadi, Gholam Hosin Vaezi,
Volume 14, Issue 6 (9-2015)
Abstract
Background: Diabetes accompanies with hormonal, biochemical changes, and metabolic damages are of body. So in this research, therapeutic effect of the blue mesocarp extract on streptozotocin diabetes has been discussed.
Methods: 30 adult Westar rats were divided into five groups six below. Witness group: that at the same time by injecting (STZ) to diabetic rats citrate buffer has been injected into them as the attribute. First experimental group: became diabetes by injecting 55mg/kg (STZ). Second experimental group and Third experimental group and Fourth experimental group: including six diabetic rats that were treated by injecting daily 100, 150& 200mg blue mesocarp extract of walnut end of week 13direct bloodletting from the heart has been achieved due to study of One way anova and a further test of TUKEY were consumed then samples were delivered to the lab for insulin hormone and blood sugar measuring
Results: In the treated group there was a meaningful decrease in blood sugar in all doses of blue mesocarp extract of walnut than diabetic group and also a meaningful increase in serum's ansoline level and body weight in treated group than diabetic group. This study for the first time showed that using blue mesocarp extract of walnut in long period, meaningfully decreases blood sugar in diabetic rats and it causes the meaningful increase of serum's ansoline in treated group.
Conclusion: diabetes redounds to decrease of ansoline hormone and increase of blood sugar by making free radicals and oxidative stresses. Blue mesocarp extract with ability of prevent and treating of oxidative stresses has an important role in improving the consequences of diabetes and also the increase of ansoline hormone.
Hamid Mohammad Sadeghi, Amirhossein Mansourabadi, Sepehr Emami, Mohammad Reza Nahvinejad, Maryam Moogooei,
Volume 14, Issue 6 (9-2015)
Abstract
Background: Diabetes is a metabolic disorder caused by insufficient production of insulin or insulin receptors deficiency. It is now the major cause of morbidity and hospitalization in patients with a significant financial burden to the society. The aim of this study was to evaluate the effect of Ziziphora ethanolic extract on active pancreatic beta cells on streptozotocin induced diabetic mice.
Methods: In this study, 36 mice were used and divided in to 6 group such as control group, diabetic control and experimental groups which were exposed to dose of 100, 150, 200 and 300mg/kg. STZ intraperitoneally at a dose of 70 mg / kg was administered. In order to determine the number of active pancreatic beta cells, the mice were anesthetized by diethyl ether after treatment with the extracts for 18days. The pancreases were removed from the mice and fixated in 4% formaldehyde afterwards, the pancreases were prepared for sectioning. Three-micron sections were prepared from the samples, and the number of active beta cells was evaluated by an immunocytochemistry kit.
Results: The results showed that the hydroalcoholic extracts of Ziziphora clinopodioides lam (100, 150, 200 and 300 mg/kg) increased the number of beta cells and insulin secretion in diabetic mice, compared to control diabetic mice. In other words, this plant could effectively increase the activity of beta cells in diabetic mice, compared to control mice. Therefore, Ziziphora clinopodioides lam could reduce serum glucose level in diabetic animals by increasing insulin secretion.
Conclusion: According to the results, the hydroalcoholic extract of Ziziphora clinopodioides lam had hypoglycemic effects in streptozotocin-diabetic mice by stimulating insulin secretion from pancreatic beta cells. Therefore, based on the obtained findings, application of this plant may be useful.
Mehdi Sadeghian, Zatollah Asemi, Maryam Karamali, Parvane Saneei, Esmaillzadeh Ahmad ,
Volume 15, Issue 1 (1-2016)
Abstract
Background: This study was designed to assess the effects of calcium and vitamin D supplementation on the metabolic status of pregnant women with gestational diabetes mellitus (GDM).
Methods: This randomized placebo-controlled trial was performed at maternity clinics affiliated to Kashan University of Medical Sciences, Kashan, Iran. Participants were 56 women with GDM at 24–28 weeks gestation (18 to 40 years of age). Subjects were randomly assigned to receive calcium plus vitamin D supplements or placebo. All study participants were blinded to group assignment. Individuals in the calcium–vita- min D group (n = 28) received 1,000 mg calcium per day and a 50,000 U vitamin D3 pearl twice during the study (at study baseline and on day 21 of the intervention), and those in the placebo group (n = 28) received two placebos at the mentioned times. Fasting blood samples were taken at study baseline and after 6 weeks of intervention.
Results: The study was completed by 51 participants (calcium–vitamin D n = 25, placebo n =26). However, as the analysis was based on an intention-to-treat approach, all 56 women with GDM (28 in each group) were included in the final analysis. After the administration of calcium plus vitamin D supplements, we observed a significant reduction in fasting plasma glucose (p < 0.001), serum insulin levels (p = 0.02) and HOMA-IR (p = 0.001) and a significant increase in QUICKI (p = 0.003) compared with placebo. In addition, a significant reduction in serum LDL-cholesterol (P=0.02) and total cholesterol: HDL-cholesterol ratio (p = 0.003) and a significant elevation in HDL-cholesterol levels (p = 0.01) was seen after intervention in the calcium–vitamin D group compared with placebo. In addition, calcium plus vitamin D supplementation resulted in a significant increase in GSH (p =0.03) and prevented a rise in MDA levels (p = 0.03) compared with placebo.
Conclusion: Calcium plus vitamin D supplementation in women with GDM had beneficial effects on their metabolic profile.
Bita Faam, Asieh Zahedi, Mehdi Hedayati, Fereidoun Azizi, Mohammad Ali Mansournia, Maryam Daneshpour,
Volume 15, Issue 1 (1-2016)
Abstract
Background: The scavenger receptor class B type I (SR-BI), as the high density lipoprotein cholesterol (HDL-C) receptor, is a key component in the reverse cholesterol transportation. The objective of this study was to assess the association between exon1 (G→A) polymorphism of SR-BI gene and lipid profiles among the Tehran Lipid and Glucose Study (TLGS) population.
Methods: This cross-sectional study included 774 adults (322 males and 452 females) aged 20–70 years, who were randomly selected from among TLGS population. Anthropometrical and biochemical variables for participants were measured. Selected SR-BI gene polymorphism was determined with restriction fragment length polymorphism (RFLP) using the Alu restriction enzyme.
Results: according to the results of current study, in the Tehran population, the allele frequency of SR-BI (G→A) polymorphism was 0.159 for an allele (minor allele) and 0.841 for G allele. Allele frequencies were in conformity with Hardy–Weinberg equilibrium. The result of this study showed that Subjects with the less common allele (allele A), after adjusting for age, have lower HDL-CandHDL3concentrations (p=0.046, p=0.041 respectively).
Conclusion: lipid disorders are caused by the interaction of environmental and genetic factors; therefore, exon1 (G→A) polymorphism of SR-BI gene could not be the only cause for the abnormality in the HDL-C levels. In future, this polymorphism may be use as a molecular marker for diagnosis.
Maryam Peimani, Camelia Rambod, Robabeh Ghodsi, Ensieh Nasli Esfahani,
Volume 15, Issue 4 (5-2016)
Abstract
Background: The objective of the current study is to assess the effectiveness of Mobile Short Message Service (SMS) intervention on education of basic self-care skills in patients with type 2 diabetes. Moreover, we aimed to determine whether delivering individually-tailored educational messages can be more effective than general educational messages.
Methods: A total of 150 patients with diabetes type 2 were randomized into three groups: tailored SMS group, non-tailored SMS group, and the control group. Biochemical parameters including HbA1c, FBS, lipid profile were evaluated for the three groups at baseline and after 12 weeks. Moreover, self-care Inventory (SCI), Diabetes Management Self-Efficacy Scale (DMSES) and Diabetes Self -Care Barriers assessment scale for Older Adults (DSCB-OA) were completed. In the tailored SMS group, each person received 75% of their messages based on the top two barriers to adherence that they had experienced and reported in their scale. In the non-tailored SMS group, random messages were sent to every patient.
Results: After12 weeks, although HgA1c levels did not significantly change, significant decline was observed in FBS and mean BMI in both intervention groups. Mean SCI-R scores significantly increased and mean DSCB and DMSES scores significantly decreased in both tailored and non-tailored SMS groups. In the control group, mean SCI-R scores decreased and mean DSCB and DMSES scores significantly increased (P< 0.001).
Conclusion: Sending short text messages as a method of education in conjunction with conventional diabetes treatment can improve glycemic control and positively influence other aspects of diabetes self-care. According to our findings, sending SMS regularly in particular times appears to be as effective as sending individually tailored messages.
Esmat Mosayebi, Maryam Sharifi, Ahmad Abedi,
Volume 15, Issue 4 (5-2016)
Abstract
Background: Diabetes is a chronic and prevalent disease. In recent years, its prevalence has increased because of lifestyle changes, immobility and subsequent obesity. The increase in diabetes prevalence has provoked multiple and scattered interventions by specialists and health care providers in order to control and regulate blood sugar and its related factors. The purpose of this study was to collect and integrate the results of these interventions in two fields of psychological and sport interventions and to investigate the impact of them on control of Glycosylated haemoglonin (HbA1c) in patients with diabetes by meta-analysis method.
Methods: For this purpose 38 acceptable studies (19 sport interventions and 19 psychological interventions), in terms of methodology, were selected and meta-analysis performed on them. This study is based on 38 effect sizes and research instrument is checklist of meta-analysis.
Results: The study findings showed that the effect size of psychological interventions on control of Glycosylated haemoglonbin is 0.67 (p<0.00001) and the effect size of sport interventions is 0.79 (p<0.00001).
Conclusion: according to Cohen’s chart, the effect size of both psychological and sport intervention on control of Glycosylated haemoglonin in patients with diabetes is medium. However, the effectiveness of sport interventions have been obtained more than the psychological intervention
Maryam Mortezaee, Abbasali Raz, Shole Mansouri, Zohreh Annabestani, Zahra Mirzaeezadeh, Bagher Larijani, Mehrdad Hashemi, Kobra Omidfar,
Volume 15, Issue 5 (7-2016)
Abstract
Background: Insulin resistance and progressive β-cells failure are the key factors in type 2 diabetes mellitus (T2DM) pathogenesis. Many studies support a primary role of RBP4 in insulin resistance and suggest that genetic variations which alter the expression level of RBP4 might influence the risk of T2DM and its complications. Diabetic foot is one of the main complications of diabetes leading to disability and hospitalization. In addition, it reduces quality of life and imposes great cost to patients. The purpose of this study was to evaluate the correlation between two single nucleotide polymorphisms (rs10882273 and rs10882283) of RBP4 genes with diabetic foot ulcer in order to identify a biomarker for prediction of diabetic foot ulcer.
Methods: This is a case-control study. Two single nucleotide polymorphisms of RBP4 genes were genotyped by hit Tetra ARMS PCR technique. In this study, 100 and 133 diabetic patients with and without foot ulcer were selected as the cases and controls, respectively.
Results: The Chi-square test revealed no significant difference in frequency of TT, CC and TC alleles of rsl0882273 between case and control groups (P=0.414). Also, Comparison of AA, CC and AC alleles of rsl0882283 in both groups did not show significant difference (P=0.85).
Conclusion: According to this study, there is no relationship between two single nucleotide polymorphisms of RBP4 genes (rs10882273 and rs10882283) with diabetic foot ulcer in type2 diabetes patients.
Sahba Aryandoost, Parvaneh Nazarali, Rozita Fathi, Farshad Sohbatzadeh,
Volume 16, Issue 2 (1-2017)
Abstract
Background: Diabetic foot wound considered as cause of disability in diabetic's patients. And despite the progress made in the diagnosis and treatment of diabetes, since diabetic foot problem has not been resolved. The aim of this study was to investigate the effect of endurance training and cold plasma on wound healing in diabetic rats.
Methods: 25 male Wistar rats were divided randomly into 5 groups (n=5). The once injected intraperitoneally with a concentration of 40mg/kg of body weight was taken. 4mm punch biopsy wounds were used to create skin wound. The exercise protocol, consists of 60minutes of running on a treadmill at a speed of 25m/min, 5days a week for 4times in a week. The whole process of plasma irradiation on wound took over 8times at each of the plasma samples for 10 minutes under direct radiation at a distance of 20 mm from the tip, respectively. The wound picture was taken with the camera Dino-Lite. Given the normal distribution of data to test hypotheses of parametric tests one-way ANOVA and repeated measure ANOVA were used to determine differences (P≤ 0.05).
Results: The findings showed that the difference between exercise+diabetes group and Ctrl+diabetes group wasn’t significant. In addition, the difference between plasma+diabetes group and Ctrl+diabetes group wasn’t significant. However, the significant difference was between plasma+training+diabetes group and Ctrl+diabetes group.
Conclusion: This is the first time that the combination of exercise and cold plasma used for wound healing in diabetes and have significantly accelerated wound healing in diabetic mice.
Maryam Hor, Golam Reza Manshaee,
Volume 16, Issue 6 (10-2017)
Abstract
Background: diabetes causes psychological problems besides physiologic ones for the people. Therefore the purpose of the present study was to determine the effectiveness of acceptance and commitment therapy on mental health of the patients with type 2 diabetes in the city of Isfahan.
Methods: the research method was semi-experimental and its design was pretest, post-test with control group and follow-up stage. The statistical population of included diabetic patients in Isfahan charity diabetes center in 2015. In order to do the study, 30 patients with type 2 diabetes were selected through improbable available and purposeful sampling method and put into experimental and control groups (15 in the experimental and 15 in the control group). The applied instruments were General health questionnaire (GHQ) and demographic questionnaire. After administering pretest, the experimental group received acceptance and commitment therapy during eight ninety-minute sessions in eight weeks while the control group didn’t have such intervention. After finishing therapeutic session, the people in two groups had the post test. After two months the follow-up test was administered. After data collection, the data analysis was conducted via COVARISNCE statistical analysis method through SPSS21 software.
Results: the results showed that there is a significant difference between experimental and control group between pretest and posttest scores (P<0.001). The results revealed that the effect of treatment was stable at the follow-up stage (P<0.001).
Conclusion: considering the significant effect of acceptance and commitment therapy on the mental health of the patients with type 2 diabetes, it is suggested to use this method to increase mental health of these patients.
Manijeh Dehi , Kian Norozi, Parvaneh Aghajari, Maryam Khoahbakht, Nazila Vosoghi,
Volume 17, Issue 1 (3-2018)
Abstract
Background: The diabetes is one of the most common chronic diseases in the world. One of the most considerable factor in case of a diabetic patient is quality of life. and the home visit can be effective. The present study aims to investigate the effects of home visits on quality of life type II diabetes.
Methods: the present study is a clinical trial study for which 61 patients suffering type II diabetes visiting healthcare homes in the villages in Maragheh, were selected considering the criteria for entering the study and using random sampling method. Later on, in order to control the limitations, subjects were homogenized according to their age, marital status, education and the period of their illness. Then, they were divided into two control and experimental groups. then all units of study completed Quality of life questionnair before and after the intervention (6 month structured program of home visits). Data were analysed by SPSS and descriptive and analytic stastics (t test)
Results: The finding showed there was a significant difference between mean Quality of life in case group befor and after the intervention (P< 0/01). But there was no significant between mean Quality of life in control group befor and after the intervention (P>o/o5).
Conclusion: Based on the finding of this study, home visit has been effective on the improvement of Quality of life, and the nurses by appropriate intervention and home visit can help to improve quality of life.
Seyed Ali Hosseini, Fatemeh Rezvanipour, Nasibeh Kazemi, Omidreza Salehi, Maryam Kasraeian,
Volume 17, Issue 1 (3-2018)
Abstract
Background: Gestational diabetes in on of common complications of pregnancy which has different complications for fetus and mother. Aim of present study was to review the effect of six weeks aqua training in second trimester of pregnancy on visfatin and glucose tolerance of gestational diabetic women.
Methods: In this semi experimental research 24 gestational diabetic mothers who recourse to hafez clinic of shiraz city which were in 23- 24 week of pregnancy select as sample and divided in two groups of 12 persons of aqua training and control. Aqua training group trained aqua trainings 6 weeks, 3 sessions per week and 45 minutes per session. In this period of the time control group has just their daily activities. For measure the research variables fasting blood sample gathered from antecubital vein in pretest and post test.
Results: Six weeks aqua training in second trimester of pregnancy has significant effect on increase of visfatin and decrease of glucose tolerance of gestational diabetic women (p=0.001).
Conclusion: It seems that for improvement of visfatin levels and glucose tolerance of gestational diabetic women can use six weeks aqua training in second trimester of pregnancy.
Rasoul Soleimani Moghadam, Shabnam Mohammadi , Nayereh Kargar Kakhki , Maryam Mohammadi, Abolfazl Ghadimifar , Abolfazl Ahmadnejad , Atefeh Talaei Bagestani , Mahmoud Reza Nemat Allahi , Alireza Mohammadzadeh , Majid Ghayour Mobarhan, Fatemeh Mohammadzadeh ,
Volume 17, Issue 3 (3-2018)
Abstract
Background: According to the World Health Organization, cardiovascular diseases are the leading cause of death. Behavior modification to improve lifestyle habits can reduce the risk of cardiovascular disease. The aim of this study was to investigate the health promoting lifestyle in Patients with cardiovascular disease in 2014.
Methods: After approval of the study, 352 patients with cardiovascular disease in Gonabad city were enrolled 2014. Data were collected using Health Promoting Lifestyle Promoting (HPLP2) questionnaire. Then analyzed using SPSS software and the Mann-Whitney and Kruskal-Wallis tests. The significance level of P value was considered to be less than 0.05.
Results: Three hundred and fifty-two patients (232 females and 120 males) were recruited, with a mean age of 61.89 ± 1.34 years. The highest mean score of lifestyle was 24.45 ± 8.05 in personal relationships and the lowest was 12.65 ± 5.60 in the area of stress management. All structures had the direct impact on the lifestyle that the most direct impact was social relations (R2= 0.329) and the least direct impact was stress management (R2= 0.164) and the strongest predictor of lifestyle in the mechanisms related to physical activity with the overall effect 14.38 was based on the pattern walker.
Conclusion: Considering, life style has a significant effect on cardiovascular disease. It is possible to improve the lifestyle of patients by providing steps to prevent and control this disease.
Maryam Zangeneh, Nahid Mohamadi, Tahereh Kolahi, Ghodratolah Roshanei, Masood Khodaveisi, Arezoo Shayan,
Volume 17, Issue 3 (3-2018)
Abstract
Background: Gestational diabetes is one of the most common metabolic disorders during pregnancy. The purpose of this study was to determine Prevalence of Gestational Diabetes Mellitus in Pregnant Women Referred to Therapeutic and Health Centers in Hamadan Town.
Methods: This descriptive-sectional study was done in the year2014 on 620 pregnant women Referred to The health Centers in Hamadan Town. The necessary information was collected by means of a self-made
Questionnaire. The scientific validity of the questionnaire Comments 15 members of the faculty of nursing and midwifery. The necessary amendments were made. To determine the reliability question a pilot study on 10 patients was performed twice with an interval of 10 days and offer 0/91 reliability was confirmed Then the data was analyzed by using SPSS software, independent Fisher test, Chi-square and a=0.05 was taken as the significant level.
Results: 110 of the 620 cases studied (almost 17.1%) suffered from gestational diabetes mellitus and 38 cases of all (almost 6.1%) had overt diabetes. Mean age of the pregnant women was30.6±5 and BMI25.3±4.1 their mean number of pergment was 1.6±0.8. Increasing the hours of mother's work at home, body mass index, household size, number and history of abortion, number of pregnancies and delivery, and the history of diabetes in the family, the chance of having diabetes also significantly increases (P<0.05).
Conclusion: Regarding the great importance of gestational diabetes and its complications on the fetus, diabetes preventive practices demand special attention to pregnant women Regarding the trend of increasing the incidence of pregnant women to gestational diabetes mellitus and the effect of demographic and obstetric factors on its development, screening for women before admission for diabetes and healthy lifestyle education is recommended.
Maryam Hor, Asghar Aghaei, Ahmad Abedi, Mohsen Golparvar,
Volume 17, Issue 5 (7-2018)
Abstract
Background: Diabetes is a chronic disease with consequences affecting many aspects and dimensions of life. Patients experience relates to many aspects of their lives because the disease involves their whole life.
The present study aims at defining the role of life style in patient's life. Reviewing their lived-experience can provide basic solutions to reform the life style of patients with diabetes.
Method: in this phenomenology qualitative research, sampling was done among patients referred to Isfahan Diabetes Charity Center in a purposeful manner with the most possible variety. A number of 33 women with diabetes in the age range of 35 to 69 years with an experience of at least one year of living with diabetes and without a history of acute mental disease were chosen. Gradual sampling was conducted from January 2017 to March 2017. Patients took part in 45 to 50 minute semi-structured interviews. The interviews were recorded and then the Colaizzi method format was analyzed.
Results: analysis process of data gathered from these patients' lived-experiences, resulted in extracting four themes including physical health, psychologic health, spiritual health and social health.
Conclusion: In order to reform the life style of patient's' with diabetes, a general comprehensive attitude in way of living is needed. Understanding the lived-experience and analyzing the life style experiences results in the field of health among patients with diabetes can assist the health care staff in providing better services and prevent returns to the inappropriate life style in the future.
Mahdi Bakhtiari Moghadam, Hossein Shabaninejad, Alireza Shams Moatar, Maryam Sarikhani, Asra Asgharzadeh,
Volume 17, Issue 6 (10-2018)
Abstract
Background: Effect of mobile text message on blood glucose (HbA1c) control in providing type 2 diabetes care (diabetes mellitus non insulin dependent).
Methods: The present study is a systematic review with meta-analysis. A search of the most important electronic medical databases of medical resources from December 1992 to January 2017 in a systematic manner, including: CRD, Ovid Medline, PubMed, Cochrane Library, and moreover, by referring to the resources found in the articles and manual search on the site. Related to this technology and, if necessary, contacting experts. All randomized clinical trials and cohort studies were reviewed.
Results: Participants included nine studies (818), all randomized clinical trials, and quality assessment. The average decrease in Mobile SMS Services users compared to the control group (SMD-0.324, 95% CI, -0.526 to -0.121; I2 = 51.0). The analysis of subgroups showed that young patients are more likely to use diabetes programs, and the size of the effect increases with short intervals of interventions and the size of large samples.
Conclusion: Mobile SMS services may be considered as an effective component for helping control glycosylated hemoglobin and as a side intervention for the care of patients with type 2 diabetes.
Mohammad Soltanizadeh, Maryam Montazeri, Zohreh Latifi,
Volume 18, Issue 2 (2-2019)
Abstract
Background: Type 1 diabetes is one of the most common metabolic abnormalities in childhood, with one in every 400 to 600 children affected by the disease. The aim of study was to evaluate the effectiveness of cognitive-behavioral therapy on emotional regulation of children with type 1 diabetes.
Methods: The research design was a quasi-experimental design with pre-test, post-test and follow-up and control group. The sample of 25 children aged 8 to 13 years with type 1 diabetes was diagnosed by endocrinologist. They were randomly assigned control (n = 15) and experimental (n = 10) groups. Subjects completed an cognitive emotion regulation questionnaire (Garnefski et al., 2007) in a pre-test, post-test, and one month and a half follow-up. Data were analyzed using repeated measure analysis of variances.
Results: The results of this study showed that there was a significant difference between the mean scores of emotional regulation in pre-test, post-test and follow-up (P <0.01). Also, there was a significant difference between emotional regulation in the experimental and control groups (P <0.05).
Conclusion: Cognitive-behavioral therapy can be considered as an effective intervention to regulate the excitement of children with diabetes.
Narges Shafaei Bajestani, Maryam Aradmehr, Ensieh Nasli Esfahani, Behrooz Khiabani Tanha,
Volume 18, Issue 2 (2-2019)
Abstract
Background: Diabetes is one of the most dangerous and common diseases of the modern world. Since medical research usually has limited data available and medical data is very ambiguous, it seems appropriate to use the fuzzy model to find out the relationship between input and output in medical data. None of the previous articles of fuzzy regression have been used to predict complications of diabetes, including nephropathy. Therefore, in this study, a fuzzy regression model was used to predict nephropathy in a diabetic patient.
Methods: In the present study, GFR results of previous patient experiments were used to predict a deeper horizons of GFR and ultimately to predict renal disease. Chronic kidney disease has been stratified based on the amount of GFR, that fuzzy data has been constructed based on these levels. The GFR prediction was performed in the following steps. Step 1: Define fuzzy sets based on the GFR level, which is considered for each level of a fuzzy set. Step 2: Fuzzify patient data Based on fuzzy sets. Step 3: GFR prediction with fuzzy regression model. Step 4: Defuzzifying the predictions. Step 5: Evaluating the model efficiency. The RMSE error is used to compare the performance of the model.
Results: The results of GFR prediction showed that comparison RMSE was 10.09 with using simple linear regression model and 4.24 in fuzzy model.
Conclusions: fuzzy regression model can predict nephropathy in diabetic patients.
Mohammad Azimi Alamouti , Niloufar Shayan, Maryam Momeni, Masoumeh Nouri, Azam Koohkan, Ensiyeh Hajizadeh-Saffar, Fatemeh Soltanolizadeh, Maliheh Mahmoudi, Mahin Jamshidi Makiani, Marzieh Ebrahimi,
Volume 18, Issue 3 (3-2019)
Abstract
Background: For nearly 100 years, amniotic membranes have been used to treat various types of skin wounds. Amniotic extract is one of the derivatives of amniotic membrane that contains all the properties of amniotic membrane. The aim of this study was to evaluate the safety of the amniotic membrane extract in the treatment of diabetic ulcers.
Methods: This study was an Open labeled clinical trial without control group. A total of 10 patients with Wagner Grade 2 diabetic foot ulcers were selected in both sexes. The extract was used every 48 hours in the first week and every 72 hours from the second week until the end of the wound treatment. Patients were followed up weekly until wound healing.
Results: In this study 80% of patients were men and 20% were women with mean age (56.7 ± 8.7) years. The ulcer duration was 8.9 ± 2.12 weeks. The mean area of ulcers at the time of entry into the wound group ≥ 500 mm2, 977.5 ± 201.9 and in the wound group ≤500 mm2 was 145.6 ± 36.4. At 4 weeks post treatment, the wound healing rate in the wound group was ≤500mm2 ,98.9 ± 2.40 % and in the wound group ≥mm2 500 was 92.1 ± 7.23%. in sixth week of treatment, ulcers were complete closure in both groups.
Conclusion: The results of this study suggest that the use of amniotic extract can be effective in the healing of diabetes foot ulcer without any side effects.
Neda Aghaei, Mohammad Sherafati Moghadam, Farhad Daryanoosh, Saeedeh Shadmehri, Shiva Jahani Golbar,
Volume 18, Issue 3 (3-2019)
Abstract
Background: The mTORC1 pathway is one of the important pathways for protein synthesis in the heart, which can lead to physiological or pathological hypertrophy. Diabetes can lead to defects in this pathway. The aim of this study was to examine the effect of 4 weeks’ aerobic training on the content of mTORC1 signaling pathway proteins in heart tissue of type 1 diabetes rats.
Methods: In this experimental study, 16 Sprague-Dawley male rats (mean weight of 300 ± 20 gr) were selected and after induction of diabetes by STZ was randomly assigned into two groups: diabetic training and diabetic control. The experimental group performed HIIT training for 4 weeks’ accordance with the training program (each session 42 minutes, 10-20 m/m) for 4 weeks, while the control group did not have any training program. Dependent t-test and independent T-test were used to analyze the data
Results: Significant increase was observed in the content of AKT1 (p<0.015), mTOR (p<0.001), P70S6K1 (p<0.006), 4EBP1 (p<0.05) proteins in the aerobic training group compared to control group.
Conclusion: Aerobic training for 4 weeks enabled to activate the pathway AKT1/mTOR/P70S6K1 and AKT1/mTOR/4E-BP1 in mTORC1 pathway; therefore, due to cardiac complications in type 1 diabetic patients, aerobic training can lead to protein synthesis and physiological cardiac hypertrophy through mTORC1 pathway.
