Showing 126 results for Type 2 Diabetes
Zeinab Shayeghian, Parisa Amiri, Maria E. Aguilar-Vafaie, Mohammad Ali Besharat, Mahmoud Parvin, Kobra Roohi Gilani,
Volume 14, Issue 4 (5-2015)
Abstract
Background: One of the important goals in control diabetes to maintain normal levels of glycated hemoglobin, but different social and psychological factors such as social support and alexithymia play role on process of this control. The purpose of present study was to examine the role of alexithymia on the association of social support and glycated hemoglobin in patients with type 2 diabetes. Methods: This was a cross-sectional study. The study sample consisted of 100 (60% females, 40-60 years) type 2 diabetic out-patients visiting the Labbafinejad hospital in 2013. The sample of the present study was a convenience sample. Measures of data collection included demographic and anthropometric questionnaires, Multidimensional Scale of Perceived Social Support, Toronto Alexithymia Scale and test of glycated hemoglobin. The collected data were analyzed, using multiple regression analysis. Results: Pearson's correlation coefficients showed a significant association between better reported perceived social support and lower alexithymia and glycated hemoglobin. Results of hierarchical linear regression analyses indicated that social support explained 23% and alexithymia 31% of glycated hemoglobin variance. As well as, alexithymia moderated association between perceived social support and glycated hemoglobin in patient with type 2 diabetes. Conclusion: Based on the present data, alexithymia has moderate role on the association between perceived social support and glycated hemoglobin in patient with type 2 diabetes. The results of this study highlight effective psychological factors in glycated hemoglobin which can help in the conceptualization, planning and design of treatment policies for control and treatment of type 2 diabetes.
Abodulaziz Aflakseir, Sare Raoofi, Javad Mollazadeh, Farhad Khormaei, Azam Farmani,
Volume 14, Issue 5 (7-2015)
Abstract
Background: Health locus of control is an important variable in diabetes. The aims of the present study were to investigate the role of health locus of control in predicting psychosocial adjustment to illness and compare psychosocial adjustment to illness and dimensions of health locus of control among male and female type 2 diabetic patients.
Methods: One hundred and eighteen patients were recruited via convenience sampling method from type 2 diabetic patients who were referred to the Shahid Motahari diabetes clinic in Shiraz. The participants filled Multidimensional Health Locus of Control (MHLC) and Psychosocial Adjustment to Illness Scale (PAIS).
Results: The results indicated that there were significant positive correlations between psychosocial adjustment to illness and internal health locus of control (r= .30, P &le .001) and God health locus of control (r= .18, P &le .05). Internal health locus of control (&beta= .28, P &le .01) significantly predicted psychosocial adjustment to illness. There were significant differences between male and female diabetic patients on the basis of chance health locus of control. Female patients got higher scores on chance health locus of control. Moreover, there were no significant differences between male and female diabetic patients on the basis of psychosocial adjustment to illness.
Conclusion: The findings highlighted that internal health locus of control and God health locus of control play significant role in psychosocial adjustment to illness. Therefore, it is recommended that psychologists and clinicians take the dimensions of health locus of control into considerations in the treatment of psychological problems of diabetic patients.
Jafar Sadegh Tabrizi, , Saeide Alidoost, , , ,
Volume 14, Issue 6 (9-2015)
Abstract
Background: Type 2 diabetes is one of the chronic diseases and quality of care for people with type 2 diabetes is important. Hence, measuring the quality of care for patients leads to identification of weaknesses and improves the quality of services. The aim of this study is to assess the quality of care provided to patients with type 2 diabetes by CQMH model.
Methods: This cross sectional study was conducted on 180 patients with type 2 diabetes in diabetes clinic of sina hospital in Tabriz, in 2012. Participants were selected with convenience sampling method. Validity of questionnaire was confirmed by experts. Principal Component Analysis (PCA) was used to calculate quality index. Chi-squared test, Independent T test, and ANOVA test were used to investigate association between different variables and aspects of quality (technical quality, customer quality and service quality). Statistical analysis was carried out using SPSS software version 17 and P-value &le 0.05 were considered as statistically significant level.
Results: There is a wide gap between standards and care provided for people with diabetes especially in self-management and lifestyle. Continuity of care and safety, respectively, were aspects with the highest and lowest score. Customer quality score is 72.62 (from 100) and only 9.4% of participants reached to stage 4 that shows weakness of this aspect of quality. Also, there was statistically significant relationship between customer quality score and educational level and diabetes status. (P-value &le 0/05).
Conclusion: The results of study show wide gap between standards and care provided. Also, there was wide gap between customers' expectations and providers' performance. In the other hand, self-management behavior among patients was not suitable and most of them were not able to action under stress.
Nazanin Moslehi, Firoozeh Hosseini-Esfahani, Farhad Hosseinpanah, Parvin Mirmiran, Parvane Hojjat, Fereidoun Azizi,
Volume 15, Issue 2 (1-2016)
Abstract
Background: The aim of this study was to identify major dietary patterns in Iranian adults and their associations with the risk of type 2 diabetes (T2DM).
Methods: This nested case-control study was conducted among 698 women and men with a mean age of 43.6 ± 12.0 years in the Tehran Lipid and Glucose Study (TLGS). Among participants who were free of T2DM at baseline and developed T2DM during follow-up examinations, individuals with dietary intakes data were considered as cases. Each case was matched to three T2DM free controls on sex, age, and the date of blood drawing. Major dietary patterns were identified using principal component analysis and odds ratios of T2DM were estimated using conditional logistic regression.
Results: In this study, three major dietary patterns were identified. After adjusting for diabetes risk factors, 1-SD increase in score of the dietary pattern characterized by high intake of whole grain, legumes, egg, and red meat (traditional dietary pattern) was associated with reduced risk of T2DM (OR : 0.82; 95% CI: 0.67-0.99).
Conclusion: A whole grain and legumes based dietary pattern may be associated with reduced risk of T2DM in Iranian population.
Mahnaz Seyedoshohadaee, Morteza Kaghanizade, Mohsen Nezami, Behzad Hamedani, Salman Barasteh,
Volume 15, Issue 5 (7-2016)
Abstract
Background: Type 2 diabetes mellitus is a major general health problem that causes widespread effects on the individual and social functions. The purpose of this study was to investigate the relationship between health literacy and general health in type 2 diabetic patients.
Methods: This cross-sectional study was done on 200 patients referred to the Diabetes Research Center, Tehran University of Medical Sciences in 1392. Data were collected using three questionnaires: demographic characteristics, health literacy (TOHFLA), general health (GHQ28 . Data analyses were done by using descriptive statistical tests, frequency distribution tables and tests (test t, ANOVA) using SPSS (Version 16).
Result: More than half of participants (58%) didn't have adequate health literacy and their general health was average (average: 53/7 ± 58/48). There was a significant correlation between health literacy and public health (p: 0.007, r:-0.191). Health Literacy was statistically significant with three aspect of general health, anxiety and sleep disorders (p: 0/0029, -0/154), social functioning (p: 0/013, r:-0/176) and depression (p: 0/002, r:-0/218).
Conclusion: In general, chronic diseases, including diabetes type 2 has clinical, social and psychological problems, which leads to mental and physical limitations in these people. This study showed that inadequate health literacy and public health are common problems, which indicate that diabetic patients need more education to improve their level of health literacy and general health.
Maryam Mortezaee, Abbasali Raz, Shole Mansouri, Zohreh Annabestani, Zahra Mirzaeezadeh, Bagher Larijani, Mehrdad Hashemi, Kobra Omidfar,
Volume 15, Issue 5 (7-2016)
Abstract
Background: Insulin resistance and progressive β-cells failure are the key factors in type 2 diabetes mellitus (T2DM) pathogenesis. Many studies support a primary role of RBP4 in insulin resistance and suggest that genetic variations which alter the expression level of RBP4 might influence the risk of T2DM and its complications. Diabetic foot is one of the main complications of diabetes leading to disability and hospitalization. In addition, it reduces quality of life and imposes great cost to patients. The purpose of this study was to evaluate the correlation between two single nucleotide polymorphisms (rs10882273 and rs10882283) of RBP4 genes with diabetic foot ulcer in order to identify a biomarker for prediction of diabetic foot ulcer.
Methods: This is a case-control study. Two single nucleotide polymorphisms of RBP4 genes were genotyped by hit Tetra ARMS PCR technique. In this study, 100 and 133 diabetic patients with and without foot ulcer were selected as the cases and controls, respectively.
Results: The Chi-square test revealed no significant difference in frequency of TT, CC and TC alleles of rsl0882273 between case and control groups (P=0.414). Also, Comparison of AA, CC and AC alleles of rsl0882283 in both groups did not show significant difference (P=0.85).
Conclusion: According to this study, there is no relationship between two single nucleotide polymorphisms of RBP4 genes (rs10882273 and rs10882283) with diabetic foot ulcer in type2 diabetes patients.
Leila Zamanpour, Ebrahim Banitalebi, Seyed Ehsan Amirhosseini,
Volume 15, Issue 5 (7-2016)
Abstract
Background: The purpose of this study is to the comparison of the effect of 12 weeks of sprint training and concurrent aerobic and strength training on high sensitive C-reactive protein (hs-CRP), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α) and insulin resistance in women with diabetes mellitus (T2DM)
Methods: 52 overweight female type 2 diabetic patients (age; 45-60 years old and fasting blood glucose ≥ 126 mg/dl (7.0 mmol/l)) were assessed for eligibility. Participants were assigned to intense interval training group (N=17), concurrent resistance- endurance training group (N=17) and control group (N=18). The combined strength-endurance group did 12 weeks, three sessions per week endurance training with 60 % of maximal heart rate and two session resistance training with 70 % 1-RM. Intense interval training group did three session/week of 4-10 repetition of all out 30s Wingate on ergometer were included 10 weeks of concurrent resistance- endurance training and intense interval training.
Results: The results showed that following sprint training, there were significant changes in hs-CRP (p<0.001), but it wasn’t significant following concurrent training (p=0.062). According to results, TNF-α change were not significant in intense sprint (p=0.11) and concurrent training (p=0.23). Differences were not significant for the fasting blood glucose in the intense interval training groups (p=0.000). Serum insulin levels showed significant increases in the SIT (p<0.000) and concurrent training (p=0.000) significantly. The data showed significant differences in insulin resistance index (HOMA-IR) in intense interval training (p=0.000) and concurrent resistance- endurance training (p=0.008). ANCOVA test showed no significant difference in fasting blood glucose concentrations (P=0.171).
Conclusion: Intense sprint training compare to concurrent strength-endurance training can have better inflammatory status for patients with type 2diabete.
Marzieh Jahandar, Morteza Badeleh, Mohammad Taghi Badeleh, Shahram Mohamad Khani,
Volume 15, Issue 6 (7-2016)
Abstract
Background: This study was planned to investigate the effectiveness of a short Cognitive Behavioral Group Intervention for Diabetes Mellitus Disease (CBGI-CHD) on quality of life and illness Perception in patients with type 2 diabetes disease.
Methods: Twenty eight patients with type 2 diabetes mellitus who were the members of Iran Diabetes Association, were selected through voluntary accessible sampling .Type 2 diabetes patients were randomly assigned in a 12-week (2.5 –h sessions) cognitive behavioral group intervention for Diabetes Mellitus Disease (n=14) or to a control group (n=14) that received usual care. Quality of life were measured using a Persian version quality of life questionnaire(WHQOL-BREF) , illness Perception were measured Using a brief Illness Perception Questionnaire( brief IpQ ) before and directly after intervention. Data were analyzed with SPSS 19 software, descriptive statistics, covariance analysis and
Results: Experiment group showed significant increases in quality of life and illness Perception at post–test, compared with control group (p< %5).In addition ,intervention in, quality of life dimensions was significant for The experimental group .(p< %5).except the environment dimension.(P>%5).
Conclusion: The results indicate that CBGI-CHD can improve quality of life and illness Perception in patients with type 2diabetes mellitus. The future researches with longer pursuing periods for reviewing efficacy continuation is suggested
Mir Hojat Mousavinezhad, Hassan Matin Homaee, Mohamad Ali Azarbaijan, Maghsood Piri,
Volume 15, Issue 6 (7-2016)
Abstract
Background: Exercise training is identified as a beneficial component of diabetes treatment plan. Angiogenesis process in diabetics can be affected by exercise activity. The purpose of this study is to determine the effect of aerobic exercise on the expression of mir-126 and capillary density in the cardiac tissue of diabetic rats.
Methods: Twenty diabetic male Wistar rats (mean weight, 191.9±10.85) were divided into two groups of control (n=10) and training (n=10) and the groups were matched based on weight. 48 hours after the last training session, cardiac tissue samples were taken after an overnight fast. Mir-126 expression was used through Real Time PCR. Also, immunohistochemistry (alkaline phosphatase activity) was used to measure the cardiac muscle capillary density.
Results: Independent t-test showed that the 8-week aerobic training significantly increased the expression of mir-126(p=0.001) and capillary density (p=0.018) of cardiac tissue in the exercise group compared to the control group.
Conclusion: The results of this study indicate that the development of angiogenesis by aerobic exercise in diabetic conditions; can be expressed as a non-drug treatments for aerobic exercise and can be used to improve heart perfusion.
Malihe Akbari Abdolabadi, Bahram Mohebbi, Roya Sadeghi, Azar Tol, Mahmood Mahmoudi Majdabadi,
Volume 16, Issue 1 (1-2017)
Abstract
Background: Overcoming barriers associated with diabetes is considered a logical infrastructure to empower diabetic patients in management of living with diabetes and identify factors which affect these barriers. This study aimed to determine the effect of an educational intervention based on the BASNEF model on barriers to awareness, lifestyle, adaptation, and support in living with diabetes in patients with type 2 diabetes and it's related factors.
Methods: This was a quasi-experimental study which. Performed among 168 patients with type 2 diabetes referred to health centers of Beheshti University of Medical Sciences from August to September 2014. Before the educational intervention, questionnaires of life barriers and the BASNEF structures were completed. After pre-test, the patients were randomly allocated to the case and control groups based on randomizing four block design. Only in the intervention group patients received six education sessions of 45 to 60 minutes that fifth education session with their families, and related staff. The educational program was designed based on the BASNEF constructs (Knowledge, attitude, subjective norm, enabling factors and behavioral intention), and educational content was developed based on the barriers to living with diabetes (awareness, lifestyle, adaptation, and protection). Data analyzed Spss stafware version 20 utelized to data analysis using statistical tests such as independent sample t-test, paired t test, Wilcoxon, McNemar test, and Mann-Whitney U
Results: Our findings showed that there was a significant difference between a score received on components of barriers to of living with diabetes (awareness, lifestyle, adaptation, and protection) and variable of the BASNEF model (knowledge, attitude, subjective norm, enabling factors and behavioral intention) before and after the educational intervention the significant level was set less than 0.05 (P<0.05).
Conclusion: Education in type 2 diabetic patients based on BASNEF, as a model for effective education, can lead to dimensions barriers reduction in (awareness, lifestyle, adaptation, and protection).
Mehdi Zarei, Mohamadreza Hamedinia, Amirhossein Haghighi, Raha Noorafshar, Sara Amini,
Volume 16, Issue 1 (1-2017)
Abstract
Background: The purpose of this study was to compare effects of three combined aerobic-resistance exercise training protocols with different intensities on metabolic control and Visfatin levels in men with type 2 diabetes.
Methods: 43 male patients with type 2 diabetes were randomly divided into 4 groups (three combined aerobic-resistance exercise training groups 1, 2, 3 and control). Training groups performed combined aerobic-resistance exercises for 12weeks, 3 times a week with given intensities )group 1:resistance 50-60% one repetition maximum- aerobic 70-80%maximum heart rate, group 2:resistance 60-70% one repetition maximum- aerobic 60-70% maximum heart rate and group 3:resistance 70-80% one repetition maximum- aerobic 50-60% maximum heart rate). Blood sampling to determine the levels of Visfatin, insulin, HbA1c, fasting glucose before and after 12weeks, were conducted.
Results: Visfatin levels and HbA1c in all training groups and fasting glucose in 2 combined training groups significantly decreased compared with control group (P<0.05). Vo2max was significantly increased in all training groups (P<0.05). No significant difference were observed between groups in body weight, Body mass index, fat mass, insulin levels and resistance insulin.
Conclusion: 12 weeks of combined aerobic-resistance exercise training protocols with were executed intensities through decreasing Visfatin and HbA1c levels and improving aerobic capacity could be helpful in patient with type 2diabetes. In addition to the above benefits, combined exercise training protocols of with intensity of 60-70% maximum heart rate–intensity 60-70% repetition maximum due to reducing fasting blood glucose could give greater benefits to patients.
Azar Tol, Bahram Mohebbi, Roya Sadeghi, Mehdi Yaseri, Malihe Akbari Abdolabadi, Fateme Dadrast, Parvin Abassi Borojeni,
Volume 16, Issue 1 (1-2017)
Abstract
Background: Improving self-care behaviors happened by self-efficacy which result in better quality of life. Current study aimed at assessing the perceived coping self-efficacy predictors among patients with type 2 diabetes referees to health centers affiliated to Tehran University of Medical Sciences.
Methods: In this cross sectional study which was descriptive and analytical one, perceived coping self-efficacy and its effective factors assessed among 536 type 2 diabetic patients referee to Tehran University of medical Sciences using random sampling based on 11-likert scale questionnaire. This questionnaire included 11 items in demographic variables and 24 items in perceived coping self-efficacy. Collected data analyzed by SPSS version 23 using MANCOVA.
Results: Study findings revealed that age (P=0.013), level of education (P<0.036), and HbA1c (P=0.004) had significant relation with total score of perceived coping self-efficacy. But, variables such as gender, occupation, disease duration, marital status, family history and history of chronic disease had no relation with scales of perceived coping self-efficacy.
Conclusion: Planning theory based intervention programs to improve coping self-efficacy among diabetic patients in low socioeconomic status population and poor diabetes control is recommended.
Fahimeh Kazemi, Saleh Zahedi Asl,
Volume 16, Issue 2 (1-2017)
Abstract
Background: Recently the role of apelin in inflammation has been known. However, the effect of exercise training-induced cytokine apelin in diabetes status hasn’t been investigated. The purpose of this study was to determine the atni-inflammation effect of 8-week aerobic training on apelin plasma concentration in diabetic male rats.
Methods: Twenty eight diabetic male Wistar rats were randomly divided into 3 groups: Non-diabetic (n=9), control diabetic (n=9) and trained diabetic (n=10). Type 2 diabetes was induced by intraperitoneal injection of nicotinamide (95 mg/kg body weight) and streptozotocin (60 mg/kg body weight). The training group ran 8-week on treadmill progressively for 45 min at a speed of 24 m/min and a 5% grade. After the training, plasma concentrations of glucose, insulin, TNF-α and apelin were measured and HOMA-IR was calculated. One-way analysis of variance (ANOVA) and Pearson’s correlation was used for analyzing data. P<0.05 was considered to be statistically significant.
Results: Results showed a significant decrease in plasma concentrations of glucose, insulin and TNF-α and HOMA-IR in trained diabetic vs control diabetic group, a significant increase in plasma concentration of apelin in trained diabetic group vs non-diabetic and control diabetic group and a significant negative correlation between plasma concentrations of apelin and TNF-α in trained diabetic group.
Conclusion: It appears that 8-week aerobic training by improvement of insulin sensitivity and decrease of inflammation can increase plasma concentration of apelin in diabetic male rats.
Marzieh Arshadi Mashkani, Mahsa Mohammad Amoli, Iman Salahshorifar, Farideh Razi,
Volume 16, Issue 3 (3-2017)
Abstract
Background: Diabetes is the most common endocrine disorder that affects many people every year. Diabetic nephropathy is main complication of diabetes type 2. Renoprotective effects of vitamin “D” in chronic kidney disease have been reported that including diabetic nephropathy. The purpose of this study is to investigate the association between polymorphism (rs731236 (Taq1)) at gene receptor vitamin D (VDR), and the risk of diabetic nephropathy in patients with type 2 diabetes.
Methods In this case-control study, 104 patients with type 2 diabetes and nephropathy, 100 patients with type 2 diabetes and no nephropathy, and 98 people without diabetes and nephropathy who referred to the Diabetes Clinic of Tehran University of Medical Sciences were included . Clinical data were obtained and biochemical parameters were measured. The DNA samples were extracted from blood samples by phenol chloroform method. TheTaqI polymorphism (rs731236) was studied by TaqMan specific genotypes.
Results: Urea, creatinine and urine albumin values were significantly higher and glomerular filtration rate was lower in nephropathy group. Although frequency of TT genotype and also T allele was higher in nephropathy group, the difference was not significant.
Conclusion: There was no association between Taq1 polymorphism and diabetic nephropathy in the studied population
Ali Jalili, Bagher Larijani, Farideh Razi, Ensieh Nasli, Mostafa Qorbani,
Volume 16, Issue 6 (10-2017)
Abstract
Background: Diabetic nephropathy is a chronic kidney disease and of more common complications of type 2 diabetes mellitus. The current diagnostic markers of diabetic nephropathy, albumin and creatinine, are only able to catch the disease in the stage of renal damage. The aim of this study is evaluation of targeted metabolomics of serum amino acids to identify the association of the changes of serum amino acid profile with diabetes and diabetic nephropathy.
Methods: This cross-sectional study was conducted in 2015-2016 on thirty patients with type 2 diabetes subsequent diabetic nephropathy and thirty type 2 diabetic patients without nephropathy attending diabetes clinic of endocrinology and metabolism institute and thirty non diabetic persons. Blood hemoglobin, HbA1c and BUN and also, serum albumin, uric acid and the albumin/creatinine ratio from a random urine specimen were measured by standard methods and serum amino acids level were identified using high performance liquid chromatography (HPLC). Statistical analysis ANOVA, Kruskal-Wallis, and nominal regression were used for the comparison of the investigated groups.
Results: significant differences were seen in serum levels of 8 essential, branched-chains, aromatic and 8 non-essential amino acids alanine, aspartic acid, serine, glutamine, arginine, glycine, tyrosine and ornithine between three groups. Serum levels of arginine and isoleucine were higher in the diabetic group than non-diabetics. However, Levels of amino acids serine, glutamine, glycine, threonine, tyrosine, tryptophan, methionine, valine, ornithine, and lysine in 2 groups of diabetic nephropathy and diabetes were higher than non-diabetic patients.
For every standard deviation decrease in serum levels of amino acids serine, alanine and isoleucine, in comparison to diabetic patients, the risk of diabetic nephropathy were increased 3.257 (95%CI: 0.10- 0.94, P=0.039), 2.207 (95%CI: 0.18- 0.81, P=0.039) and 2.652 (0.21- 0.96, P=0.012), respectively.
Conclusion: Since this study was conducted in patients in the early stages of the disease, reduced serum levels of the amino acids serine, leucine and alanine may be associated with development and progression of diabetic nephropathy. and in the future with more studies in this field can be used in metabolic control and improvement of the prognosis of patients with diabetic nephropathy.
Maryam Hor, Golam Reza Manshaee,
Volume 16, Issue 6 (10-2017)
Abstract
Background: diabetes causes psychological problems besides physiologic ones for the people. Therefore the purpose of the present study was to determine the effectiveness of acceptance and commitment therapy on mental health of the patients with type 2 diabetes in the city of Isfahan.
Methods: the research method was semi-experimental and its design was pretest, post-test with control group and follow-up stage. The statistical population of included diabetic patients in Isfahan charity diabetes center in 2015. In order to do the study, 30 patients with type 2 diabetes were selected through improbable available and purposeful sampling method and put into experimental and control groups (15 in the experimental and 15 in the control group). The applied instruments were General health questionnaire (GHQ) and demographic questionnaire. After administering pretest, the experimental group received acceptance and commitment therapy during eight ninety-minute sessions in eight weeks while the control group didn’t have such intervention. After finishing therapeutic session, the people in two groups had the post test. After two months the follow-up test was administered. After data collection, the data analysis was conducted via COVARISNCE statistical analysis method through SPSS21 software.
Results: the results showed that there is a significant difference between experimental and control group between pretest and posttest scores (P<0.001). The results revealed that the effect of treatment was stable at the follow-up stage (P<0.001).
Conclusion: considering the significant effect of acceptance and commitment therapy on the mental health of the patients with type 2 diabetes, it is suggested to use this method to increase mental health of these patients.
Negar Fani, Bahram Mohebbi, Roya Sadeghi, Azar Tol, Ahmadreza Shamshiri,
Volume 17, Issue 1 (3-2018)
Abstract
Background: Adherence to diet is one of the basis of diabetes management in patients with diabetes. Regarding to diabetes control, healthy lifestyle including nutritional behaviors, play an important role in preventing and managing diabetes. However, compliance with a diabetic diet is one of the most important challenges in diabetes control. This study aimed at determining the effect of educational intervention on promoting nutrition adherence among patients with type 2 diabetes referee to south health center of Tehran University of Medical Sciences based on Health Belief Model.
Methods: This interventional study was performed with216 type 2 diabetes patients as population study who referred to health centers in south of Tehran. Participants were randomly allocated to intervention and control groups.
Questionnaires were completed by both groups at baseline, three and six months after intervention. Intervention group received intervention including during the month, six training sessions for 45 to 60 minutes for group training and Q & A With the package held at meetings to assess the diabetes-related complications. SPSS software version 22 utilized to data analysis using t-test and repeated measure analysis. Significance level was set less than 0.05.
Results: Before the intervention, demographics and HBM constructs model were not significantly different in two groups. In intervention group, there were statistically significant differences between all parts of HBM after educational intervention (perceived susceptibility (p <0.001), perceived severity (p <0.001), perceived benefits (p <0.001), perceived barriers (p <0.001), cues to action (p <0.001)), also nutrition adherence (p <0.001) and HbA1c. there was no significant differences in control group after intervention.
Conclusion: According to study results, it can be concluded that education through Health Belief Model can be effective to follow in terms of improved nutrition among patients with type 2 diabetes.
Hamed Rezaei Nasab, Roohollah Ranjbar, Abdolhamid Habibi, Mohammad Taher Afshoon Pour,
Volume 17, Issue 1 (3-2018)
Abstract
visfatin secreted by various factors, including cytokines such as TNF-α and IL-6 is affected. The purpose of this study was to evaluate the effect of eight weeks of combined training (resistance circular - aerobic) visfatin concentration, IL-6 and TNF-α in obese men with type II diabetes.
Methods: The population of the research was all men with diabetes type II in District 2 of Ahwaz. Twenty four patients with diabetes type II, aged 40-55 years and fasting blood glucose lower than 200 mg /dl were selected by purposive sampling. First, the anthropometric variables and body composition were measured, then subjects were randomly divided into two groups (experimental, n=12 and control, n=12). Combined exercise training was done for 8 weeks (5 days/week, 30 to 50 minutes) for experimental group. To analyze the changes in the covariance analysis and dependent t test measured variables at a significance level of p≤05.
Result: After eight-week combined exercise training, fasting blood glucose and plasma visfatin significantly decreased p≤05. But no significant changes were observed in the levels of IL-6 and TNF-α p≥05. Also, the inverse relationship between plasma visfatin with IL-6 and TNF-α was observed (P≤ 0.05).
Conclusion: Eight weeks of combined training despite a positive effect on plasma visfatin, due to no significant changes in plasma IL-6 and TNF-α in patients with type 2 diabetes, it seems this type of exercise in reducing obesity and visceral fat and thereby reducing plasma visfatin is appropriate, but the potential change in IL-6 and TNF-α does.
Sahar Shafiee, Abbasali Raz, Neda Adibi, Masoomeh Mansouri, Zohreh Annabestani, Zahra Mirzaeezadeh, Mehrdad Hashemi, Kobra Omidfar,
Volume 17, Issue 1 (3-2018)
Abstract
Background: Type 2 diabetes is the most common type of diabetes, and a complex endocrine metabolic disorder that one of its main complications is diabetic foot ulcers. Matrix metalloproteinases (MMPs) are one of the key enzymes in the reconstruction of extracellular matrix which have proteolytic activity. The aim of this research is based on evaluating relationship between -1562 C>T allele at MMP-9 gene promoter with diabetic foot ulcer in type II diabetic patients. If such correlation proves, it can be used as a prognostic biomarker in patients with high-risk.
Methods: This is a case-control study. The single nucleotide polymorphism of -1562C>T allele of MMP9 gene promoter was genotyped by hit Tetra ARMS PCR technique in 100 diabetic patients with foot ulcer grade 1 or 2 as the case group according Wagner classification and in 100 diabetic patients without foot ulcer as the control group. Results: The Chi-square test revealed significant difference in genotype frequency of CC, CT and TT alleles of -1562C>T allele of MMP9 gene promoter between case and control groups (P=0.000).
Conclusion: According to this study, there is a relationship between -1562C>T allele of MMP9 gene promoter with diabetic foot ulcer in type2 diabetes patients. Thus we can introduce this biomarker for evaluation of risk and prognosis of diabetic foot ulcers.
Shima Keyvan, Noshiravan Khezri Moghadam, Asadollah Rajab,
Volume 17, Issue 2 (3-2018)
Abstract
Background: Diabetes is one of the most prevalent chronic illness that is closely associated with some psychological problems, particularly stress. In this case, psychological interventions can be useful. The aim of this study was to investigate effectiveness of Mindfulness Based Stress Reduction (MBSR) on psychosocial adjustment to illness in patient with type 2 diabetes.
Methods: In this study, semi-experimental method (pre-posttest) with control group was used. Population of the study included patients with type 2 diabetes that were member of Iranian Diabetes Society of Tehran. For sampling, 60 patients with type 2 diabetes were considered and then divided in two groups based on random sampling method. Psychosocial Adjustment to Illness Scale was used.
Results: ANCOVA showed that MBSR significantly effect on psychosocial adjustment to illness. Additionally, the results showed that MBSR significantly effect on attitude towards the disease and the social environment (P<0.05).
Conclusion: Findings revealed that MBSR can be effective on increasing psychosocial adjustment to illness in patients with type 2 diabetes. These findings have been inferred that patients with type 2 diabetes need to increase their psychosocial adjustment to illness.
