Showing 183 results for Mohammad
Dr. Alireza Bagheri, Dr. Hamidreza Aghaei Meybodi, Dr. Mohammadreza Mohajeri, Dr. Akbar Soltani, Dr. Ramin Heshmat, Dr. Bagher Larijani,
Volume 24, Issue 5 (12-2023)
Abstract
Background: Vitamin D (vitD3) deficiency is common in Iran. Although there are several studies on therapeutic doses of vitD3, the optimal dose is to be evolved. we compared the effects of high dose supplemental vitD3 versus its recommended dose on the serum level of 25(OH)D.
Methods: This clinical trial study is performed at Endocrine & Metabolism Research Institute in Shariati Hospital within 2008-2009. The subjects were osteopenic women older than 50 years who had been referred to Bone Densitometry laboratory. They were received either (group P) 50000u vitD3 weekly for 3 months then monthly for another 9 months, or (group M) 800u vitD3 daily for one year. 1000 mg calcium carbonate was given to both groups. Serum 25(OH)D, Calcium, Phosphorus, PTH was checked at base, 3rd, 6th and 12th month. 24h Urine for calcium was collected before and at the end of trial.
Results: Serum 25(OH)D level was significantly higher in group P at 3rd month (p<0.05), but it gradually declined and there was not statistically difference to group M. PTH decreased in both groups. Urine calcium to creatinine ratio did not rise in both groups.
Conclusion: vitD3 supplement at doses of 50000u weekly for 3 months then monthly for another 9 months as compare to 800u vitD3 daily for one year increases serum 25(OH)D at higher level without causing hypercalcemia and hypercalciuria, but it seems that more frequent doses in monthly period would be required to maintain the optimal 25(OH)D level.
Alireza Bagheri, Dr Mehdy Morady, Dr Mohammad Malekipooya, Dr Bahram Abedi,
Volume 24, Issue 5 (12-2023)
Abstract
Background: Obesity is a disease whose incidence and burden on societies around the world is increasing. Sexual performance in these patients is an important aspect that is often ignored. Therefore, the aim of the present study was to investigate the effect of a period of exercise along with electrical stimulation on the gene expression of some sex markers in testicular tissue of fasted obese rats.
Methods: In this experimental study, with a control group of 40 male rats after induction of obesity and weight gain, randomly divided into 5 groups: control, fasting-obese, fasting-endurance exercise, fasting-electrical stimulation and Fasting-endurance training-electrical stimulation were divided. Intervention groups for a period of 4 weeks under endurance sports activity (with a speed of 10 to 20 m/min and duration of 20 to 40 minutes), electrical stimulation (foot shock device for 0.5 mA and 20 minutes) and fasting were placed. After exercise and anesthesia, brain tissue was done and after molecular processes, gene expression was measured using Real time-PCR machine.
Results: The results showed that training led to a significant increase in the expression of 5-alpha reductase and aromatase genes in samples compared to the fasted obese group (P=0.0001). Also, electrical stimulation and its combination with endurance training showed a significant increase in the 5-alpha reductase gene (P=0.0001).
Conclusion: It seems that endurance training and combined electrical stimulation of both during fasting by increasing the expression of 5-alpha reductase and aromatase genes in obese samples are effective in their sexual health and lead to its improvement.
Ms. Khadigeh Zameni Jafarkolaei, Dr. Mohammadreza Esmaelzadeh Toloee,
Volume 24, Issue 5 (12-2023)
Abstract
Abstract
Background: This study aimed to compare the effects of high-intensity interval games and high intensity interval training on body composition indicators, aerobic capacity and lipid profiles of obese and overweight girls aged 10 to 12 years.
Methods: In this semi-experimental research, 30 girls (average height 149.26 ± 5.32 m, weight 67.41 ± 7.65 kg, and body mass index 30.14 ± 2.3 kg/m2) with overweight and obesity participated and were randomly divided into the groups of high intensity interval training (10), high intensity interval game (10) and the control (10). Training programs for eight weeks(3d/w), (90-85% of maximum heart rate) and 3-minute recovery (65-75% of maximum heart rate) with 4 times Repetition was done, which was done in the form of running in high intensity interval training and in the form of playing in high intensity interval game. Blood samples were taken to measure the serum levels of lipid profiles (48 hours before and after the intervention period).
Results: The two training groups compared to the control group, increased aerobic capacity and HDL and body fat percentage, TG, TC and LDL (P < 0.010) showed a significant decrease and between the two training groups in TG, LDL and HDL (P<0.01) was a significant difference, with a greater increase in HDL and a greater decrease in TG and LDL was accompanied in the high intensity game group.
Conclusion: High intensity interval games can be suggested as a more suitable solution to improve the lipid profile of obese and overweight girls.