Showing 12 results for Rahmani
Seyed Mehrdad Sulati, Arash Ghanbarian, Maziayar Rahmani, Narghes Sarbazi, Sima Alah Verdian, Fereidoun Azizi,
Volume 2, Issue 2 (17 2003)
Abstract
Background: Risk factors of cardiovascular disorders have been the subject of several studies. Recently, simultaneous high waist circumference (WC) and high serum triglyceride (Tg) has been proposed as a simple screening measure to predict non-traditional risk factors. This study has looked at the risk factors of cardiovascular disorders present in subjects with this phenotype.
Methods: Non diabetic females of age 18-65 years who had been enrolled in the Tehran Lipid and Glucose Study (TLGS) were recruited.
Based on fasting Tg and WC, subjects fell into four categories: TgHWH ( Tg>160 mg/dl, WC>80 cm), TgHWL (Tg>160 mg/dl,WC<80 cm), TgLWH(Tg<160 mg/dl,WC>80 cm) and TgLWL (Tg<160 mg/dl,WC<80 cm).
Cardiovascular risk factors including lipid profiles and anthropometric variables were compared between the categories. The prevalence of hypertension, LDL-C>130 mg/dl, total cholesterol>220 mg/dl and HDL- C<45 mg/dl were also determined in each category.
Results: 5630 subjects were studied. TgLWL and TgHWH constituted to 27.5 % and 31.9 % of subjects, respectively. Mean age of subjects dropping in TgLWL, TgLWH, TgHWL and TgHWH groups was 28±10, 39±12, 36+12 and 46±11, respectively and TgHWH subjects were significantly older than other groups (p<.001).
Systolic and diastolic blood pressures, body mass index and WC were significantly higher in TgHWH. Significantly higher levels of total cholesterol, triglycerides and LDL-C and significantly lower level of HDL-C were found in the TgHWH group. The prevalence of subjects with four or more risk factors was 61.4% in TgHWH versus 1% in TgLWL group.
Conclusion: Parallel high waist circumference and high serum triglycerides (TgHWH) can find use as a simple screening measure to predict other risk factors of cardiovascular disorders.
Arash Hossein-Nezhad, Jila Maghbooli, Seyed Masoud Arzaghi, Alireza Shafaei, Mazaher Rahmani, Bagher Larijani,
Volume 5, Issue 3 (17 2006)
Abstract
Background: Although there is increasing evidences that vitamin D is related to the occurrence of diabetes mellitus, its relation to glucose metabolism in pregnancy is not well studied. This study investigated 25-hydroxyvitamin D deficiency status in GDM pregnant women.
Methods: As a cross sectional study we recruited 741 pregnant women referred to five university educating hospital clinics. The universal screening was performed with a GCT-50g and those with plasma glucose level ≥130mg/dl, were diagnosed as GDM, if they had an impaired GTT-100g based on Carpenter and Coustan criteria. The levels of insulin was studied during OGTT-100g. Serum concentrations of 25-hydroxy vitamin D was measured too.
Results: Univeriate analysis revealed that 25 (OH) vit D concentrations were positively correlated with HOMA and ISOGTT index. Subjects with hypovitaminosis D (<12.5nmol/dl) had greater prevalence of GDM than others.
Conclusion: The results reveal a positive association between 25(OH) vit D concentrations and insulin sensitivity. Vit D deficiency is more prevalent in patients with GDM than normal pregnant women, So vit D supplementation may control glucose levels and improves outcome of pregnancy.
Mohammad Ali Bayani, Zhila Maghbouli, Arash Hossein Nezhad, Mazaher Rahmani, Abbas Kitabchi, Bagher Larijani,
Volume 5, Issue 4 (17 2006)
Abstract
Background: Gestational diabetes mellitus is a common metabolic disorder in pregnancy. Low levels of sex hormone–binding globulin level (SHBG) is associated with increased insulin resistance and hyperinsulinemia. The aim of this study was comparison of SHBG levels between gestational diabetic pregnant women and normal ones.
Methods: Serum SHBG concentration were measured in 38 women with gestational diabetes and in 143 women with normal pregnancy. The levels of Insulin, C-peptide and testosterone were measured and Insulin resistance was estimated via HOMA Index. Insulin sensitivity was estimated via QUIKE Index.
Results: Serum SHBG concentrations was significantly lower in the diabetic group (P=0.015). In a logistic regression model after adjustment of age, body mass index (BMI) and number of gravid, lower than 25 percentile of SHBG was independently effective in prediction of gestational diabetes mellitus.
Conclusion: SHBG concentrations are lower in gestational diabetic pregnant women and low levels account as a predictor of gestational diabetes mellitus.
Jila Maghbouli, Arash Hoseinnejad, Mohsen Khoshniatnikoo, Seyed Masoud Arzaghi, Mazaher Rahmani, Bagher Larijani,
Volume 6, Issue 1 (19 2006)
Abstract
Background: Few studies have investigated maternal leptin concentrations in women with pregnancies complicated by gestational diabetes mellitus (GDM), and these published results are conflicting. We examined the association between plasma leptin concentration and GDM risk.
Methods: As a cross-sectional study 741 pregnant women that referred to five university hospital clinics were recruited. The universal screening was performed with a GCT-50g and those with plasma glucose level ≥130mg/dl, were diagnosed as GDM if they had an impaired GTT-100g based on Carpenter and Coustan criteria. The level of insulin was measured during OGTT-100g. Also maternal plasma leptin concentrations were measured.
Results: GDM patients had higher age, parity, BMI, and serum leptin concentration as compare with normal pregnancies. In logistic regression model serum leptin levels were independent factor for GDM.
Conclusion: Serum leptin concentrations can predict GDM.
Ladan Giahi, Abolghasem Jazayeri, Abbas Rahimi, Mazaher Rahmani, Bagher Larijani,
Volume 6, Issue 2 (18 2006)
Abstract
Background: Plasma concentration of adiponectin was found to play an important role in regulation of glucose metabolism, insulin resistance and conditions commonly associated with obesity. The aim of this study was to assess adiponectin level and its relation with percent of body fat mass and insulin sensitivity in over-weight men.
Method: This study was conducted on two groups of type 2 diabetic (n=20) and non-diabetic (n=20) overweight adult men. Serum level of adiponectin (ELIZA), FBS (GOD-PAP), fasting insulin (immunoreactive assay) and body fat mass (Bio-electric impedance) were measured. Insulin sensitivity was calculated using QUICKI.
Results: Diabetics had significantly higher mean of fat mass% than non-diabetics (26.55± 2.87% vs. 22.93±2.64 p< 0.05), despite fairly similar BMIs (27.7 kg/m2). Adiponectin concentration was lower in diabetics (7.77 ±3.53µg/ml) than non-diabetics (8.13 ± 0.03µg/ml) however, this difference was not statistically significant. The negative correlation between adiponcetin and fat mass didn't reach statistical significance. Adiponectin positively related with insulin sensitivity in non-diabetics (r= +0.5 p= 0.04).
Conclusion: Lower level of adiponcetin in diabetics than their non-diabetic counterparts. As well as the positive association of adiponectin with insulin sensitivity confirm the suggested role of decreased level of adiponectin in conditions such as insulin resistance and diabetes.
Fatemeh Mohammadzadeh, Kobra Omidfar, Ramin Heshmat, Mazaher Rahmani, Bagher Larijani,
Volume 6, Issue 3 (17 2007)
Abstract
Background: Microalbominuria (MA) is early presentation of renal damage which acts as an independent factor of cardiovascular events in these patients. There are various methods for sampling and also different laboratory tests to measuring albominuria. The aim of this study was to compare of different urine collection methods for measuring albominuria using immunoturbidometry assay which has acceptable accuracy and sensitivity after HPLC (High Performance Lipid Chromathography).
Methods: Forty seven diabetic patients were selected for a cross-sectional study in 2006. For all patients 24-h urine sample were collected, also an overnight urine sample (8 hour long) and spot urine sample (morning time) was provided in the next day. The level of albumin in all samples were measured via immunoturbidometry assay. Then the results of agreement coefficient were accounted and comprised with each others.
Results: In this study 47 patients were selected which 46 of them were type 2 and one of them type 1 diabetic. Our results revealed significant correlation between all methods. In addition agreement coefficient (kappa) was accounted for all methods, time 24-h urine in comparison with 8 hours overnight urine, timed 24-h urine in comparison with spot urine and overnight urine samples in comparison with spot urine which were 0.876, 0.936 and 0.807 respectively.
Conclusion: Regarding significant agreement for screening of microalbominuria between different collecting methods, we suggest 8-h overnight or spot urine sampling carry out instead of 24-h urine collection.
Zahra Jamshidi Khezerlou, Sajad Ahmadizad, Mehdi Hedayati, Hiwa Rahmani, Azade Movahedi,
Volume 13, Issue 4 (5-2014)
Abstract
Background: The aim of this study was to compare responses of Visfatin and insulin resistance index to various resistance exercise protocols.
Methods: Ten healthy male subjects performed three resistance exercise protocols including maximal strength (three sets of 5 repetition at 85% of 1-RM with 3-min rest between sets), hyperthrophy (three sets of 10 repetition at 70% of 1-RM with 2-min rest between sets) and strength-endurance (three sets of 15 repetition at 55% of 1-RM with 1-min rest between sets) in three separate sessions. Two blood samples were taken before and after resistance exercise protocol. Responses to different resistance exercise protocols were compared by using repeated measures of ANOVA (3×2).
Results: Irrespective of resistance exercise protocol, results showed that plasma visfatin reduced significantly (P<0.05) in response to resistance exercise. Between group comparisons revealed that reductions in visfatin concentration in response to strength-endurance and hypertrophy protocols were significantly higher than maximal strength protocol (P<0.05). Analysis showed that not only glucose, insulin and insulin resistance index did not change in response to resistance exercise significantly, but also there was no significant difference among the responses to different resistance exercise protocols (P>0.05). In addition, there was no significant relationship between changes in visfatin and other parameters (P>0.05).
Conclusion: It could be concluded that performing strength-endurance and hypertrophy protocols that cause reductions in visfatin, possibly due to changes in growth hormone during these protocols, could be beneficial in reducing the hyperinsulinemia.
Hamid Asayesh, Mostafa Qorbani , Mohammad Parvaresh Masoud, Hossein Rahmani Anarki, Hossein Ansari, Morteza Mansourian, Aziz Rezapour, Farshad Sharifi, Rasoul Mohammadi,
Volume 13, Issue 6 (9-2014)
Abstract
Background: Health staffs have different attitudes and beliefs toward elders that have effect on their behaviors in health service delivery to elders. This study was done for determination of Golestan province health centers general practitioners (GPs) attitude toward elders.
Methods: In this cross sectional study, 152 general practitioners of Golestan province health centers were selected via random sampling. The Kogan's Attitudes toward Older People Scale (KAOPS) questionnaire was used as data gathering tools. Data analysis was done in SPSS 16 software using Pearson correlation coefficient, paired t-test, t-tests and one way ANOVA test.
Results: Mean (standard deviation) of participants age was 34.73 (6.26) years. Mean (standard deviation) of total score of attitude toward elder scale was 115.48 (10.22) (score range in scale 34-204). 54.2 percent of GPs have lower score than mean. Negative attitude mean score were higher than positive attitude mean score which was statistically significant (P= 0.0001).
Conclusion: According to our finding, only half of GPs had favorite attitude toward elder. Whereas negative attitudes were higher than positive attitude toward elder, designing some programs for change in attitude of heath care staffs is necessary.
Mostafa Qorbani, Mohammad Parvaresh Masoud, Ali Soleimani, Hossein Rahmani Anarki, Leila Ghanbari Afra, Hamid Asayesh,
Volume 16, Issue 4 (9-2017)
Abstract
Background: health care providers have different attitudes and belies toward elders that have effect on their behaviors in health service delivery to older adults. This study was done to determine the Golestan province health centers staffs attitude towards elders.
Methods: In this cross-sectional study, 152 general practitioners of Glestan province health centers were selected via random simple sampling. Demographic questionnaire and Kogan's Attitudes toward Older People Scale (KAOPS) was used as data gathering tools. Data analysis was done in SPSS 16 software environment with Pearson correlation coefficient, paired t-test, t-tests and one way ANOVA.
Results: mean and standard deviation of participants age was 34.48 (4.31) years. Mean and standard deviation of total score of attitude toward elder scale was 116.42±9.58 (score range in scale 34-204). Lower score than mean were observed in 49.3 percent of health care providers. Negative attitude mean score were higher than positive attitude mean and paired t-test showed the difference is significant (P< 0.001).
Conclusion: according to our finding, only half of participants had favorite attitude toward aged people. Whereas, negative attitudes to this age group were higher than positive attitudes, designing some programs for change in attitudes of heath care staffs is necessary.
Ameneh Marzban, Mehran Barzegaran, Samaneh Delavari, Hadi Marzban, Vahid Rahmanian,
Volume 17, Issue 6 (10-2018)
Abstract
consumption of medicinal plants, especially when conventional treatments are not able to control diabetes, and the patient needs insulin administration, is remarkable. The aim of this paper is the attitude and social behaviors of Bandar Abbas 's people to consume of herbal medicine in treatment of DM.
Methods: This descriptive cross-sectional study was conducted in 2017. In this study, 300 individuals aged 20 to 65 years were selected randomly from 10 locations in Bandar Abbas. The research instrument was a two-part questionnaire that evaluated demographic information and attitude. Data were analyzed by SPSS-24 software using descriptive statistics (mean, standard deviation and frequency), ANOVA, T-test Independent and Chi-Square tests.
Results: The mean and standard deviation of people's attitude toward using herbal drugs in the treatment of diabetes was 47.15±3.23. The mean score of attitude with gender variables (P = 0.002), age (P = 0.04) and education (P = 0.02) was statistically significant. The majority of people had their information on herbal medicines through their parents and relatives, and this difference was statistically significant in distributing the frequency of information sources in individuals. (P = 0.001)
Conclusion: According to the results of this research, people's attitude towards the use of herbal medicines in the treatment of diabetes was at a relatively good level, which can play a constructive role in the scientific and executive planning of the health and medical professions.
Marzieh Zamani, Vahid Rahmanian, Azam Namdar, Ameneh Marzban,
Volume 21, Issue 5 (1-2022)
Abstract
Background: Searching for health information and gaining knowledge plays an important role in the management of chronic diseases such as diabetes. The aim of this study was to investigate the role of information resources in self-management of diabetes in diabetic patients referred to health centers in Jahrom.
Methods: This study is a descriptive-analytical study that was performed on 393 patients with diabetes in Jahrom city and covered villages in 2018. Data collection tools included a form of personal information, a questionnaire based on the role of information sources in improving the disease of patients with diabetes, and information was collected through it and the results were statistically analyzed by spss24 software.
Results: The highest age range of the participants in this study was 45 to 60 years old (40.7%) and 67.9% of the patient population were women. 68.1% of patients with diabetes had information about their disease after infection. Most of their sources of information included physicians, family and friends, and other patients and the mass media, respectively. The most important reasons for not obtaining information in 31.9% of other patients were difficulty and lack of access to information resources.
Conclusion: The overall result of this study indicated the relatively high and good health literacy of the subjects. Also, the population who did not have knowledge about their disease were very eager to learn that this problem can be solved as much as possible by properly distributing and presenting educational resources and equalizing educational opportunities and equalization in affluent and deprived areas. The results of this research as well as its overall result can be used to improve the health and education system of the country and help improve and enhance the distribution of educational resources through proper training of health personnel and more cooperation of relevant organizations.
Leila Rahmani, Mohammad Rahman Rahimi, Shamseddin Ahmadi , Hassan Faraji,
Volume 24, Issue 4 (10-2024)
Abstract
Background: Glucose transporter4 (GLUT4) is the main glucose transporter in skeletal muscle. Impaired GLUT4 expression plays a role in the disorders of glycemic homeostasis. The aim of the present study was to investigate the combined effects of aerobic training and vitamin D3 supplementation on Glut4 protein levels and insulin resistance in the soleus muscle of diabetic rats with STZ and high-fat diet.
Methods: In 40 male Wistar rats type 2 diabetes was induced by 6 weeks high-fat diet followed by streptozotocin injection. Then rats were randomly divided into five groups: Healthy control (HC), Diabetic control (DC). Diabetes+Aerobic training (DAT), Diabetes+Vitamin D3 (DVD) and Diabetes+Aerobic training+ Vitamin D3 (DVDAT). The rats underwent eight weeks of aerobic training and vitamin D3 supplementation. 24h after last session of training and, the rats were anesthetized and soleus muscle was isolated for measurement of Glut4 protein concentrations and serum levels of insulin, glucose, vitamin D3 index were measured.
Results: One-way ANOVA showed that GLUT4 protein levels in DC group was significantly lower than HC group (P<0.001), but in DVDAT group was significantly higher than DC group (P<0.04) and DVD group (P<0.005). Also in DAT group was significantly higher than DVD (P<0.018). The HOMA-IR index also in DVDAT, DAT and DVD groups was significantly lower than DC group (P<0.001).
Conclusion: It seems that Eight weeks of aerobic training with vitamin D3 supplementation improves glucose metabolism in diabetic rats via increasing Glut4 protein levels and improving insulin resistance index.
