Showing 5 results for Anthropometric
Bagher Larijani, Maryam Ghodsi,
Volume 4, Issue 3 (5-2005)
Abstract
Leptin is a 16-kD protein which is secreted from white adipocytes and, its discovery has generated enormous interest in the regulation of energy balance. Leptin has been implicated in the regulation of food intake, energy expenditure, and whole-body energy balance in animals and human. Plasma leptin levels correlate with fat storages and respond to changes in energy balance. It was initially proposed that leptin serves a primary role as an anti-obesity hormone, but this role is commonly thwarted by leptin resistance. The profound effects of leptin on regulating body energy balance, make it as a prime candidate for drug therapies of obesity in humans and animals. Despite the recent achievements in unearthing the role of leptin in the pathophysiology of obesity, many important questions still remained that must be responded. More studies with follow-up designs and genetic evaluations are warranted to understand the comprehensive role of leptin in human. In this letter we have a review of known effects of leptin on human obesity up to now.
Hossein Fakhrzadeh, Maryam Ghodsi, Anahita Hamidi, Alireza Moayyeri, Ramin Heshmat, Rasool Poorebrahim, Masoumeh Noori, Bagher Larijani,
Volume 5, Issue 1 (8-2005)
Abstract
Background: It is well recognized that an increased body weight is often associated with increased blood pressure. Moreover, leptin an adipocyte-derived hormone is strongly suggested to have an important role in pathogenesis of the obesity. We aimed to evaluate the levels of serum leptin in association with obesity and hypertension in a sample of Iranian obese children.
Methods: Children from all the primary schools of a distinct of Tehran were screened for obesity. Children with a waist circumference equal to or above 90th percentile for their age and height were invited for the study. Anthropometric measurements were done and blood samples for fasting serum leptin levels were collected from 563 enrolled obese children. Multivariate linear regression analysis was used to evaluate relationship of various factors with obesity.
Results: Mean Serum leptin levels were 8.65 ±2.18 (ng/ml). Serum Leptin levels were higher in girls than boys (P=0.009). There were significant correlations between body mass index (BMI) and serum Leptin levels, child age, systolic and diastolic blood pressure. Systolic blood pressure and diastolic blood pressure lost their association with serum Leptin level in multivariate linear regression analysis.
Conclusion: BMI is independently associated with Leptin levels among obese children. This may affirm a role for this hormone in the pathogenesis of childhood obesity. It seems unlikely that plasma Leptin be a major mediator of association between obesity and hypertension. However, severe hyperleptinemia may act as a risk factor for increased blood pressure.
Neda Nazari, Hossein Fakhrzadeh, Farshad Sharifi, Seyed Masoud Arzaghi, Mahtab Alizadeh, Neda Mehrdad, Shervan Shoaei, Baharak Najafi, Mostafa Qorbani,
Volume 13, Issue 1 (1-2014)
Abstract
Introduction: The height measurements in the elderly are associated with several problems. In this study
we used a model to predict of the Iranian people aged height from age, shin length and forearm length.
Methods: A total 165 aged people ≥60 years were randomly selected based on medical record number of
about 800 eligible older people who lived in Kahrizak Charity Foundation. Standing height, shin length
and forearm length were measured. Data from 99 participants were used to creat a predicting multivariate
linear regression model for estimation of standing height of older men and women. The data of the rest
66 participants were used for models testing.
Result: The following equations were created:
Men height = 78.928+ (1.430× shin length) + (0.817×forearm length)-(0.176×age)
The height of women = 71.694+ (1.414×shin length) + (1.084× forearm length)-(0.277× age)
R2
were calculated as 0.63 for men and 0.52 for women. Error of estimation was +0.44 cm and it was -
0.16cm and +1.09cm for men and women respectively. Estimated heights were not significantly different
from standing statures.
Conclusion: height was predictable from shin length and for forearm lengths and also age with a
relatively small error in the estimation among Iranian older people. The error of model is more in women
than men.
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Volume 14, Issue 1 (1-2015)
Abstract
Background: Obesity is one of the most important risk factors for cardiovascular disease and genetic and environmental factors play important role in this risk factor. The aim of present study was to estimate the heritability of anthropometric variables in Tehran Lipid and Glucose Study (TLGS) families.
Methods: In this cross-sectional study, 529 two generation families were selected from among phase III TLGS. At least two members of the families were overweight or obese. Anthropometric variables, resting energy expenditure (REE) and body size index (BS) were determined. The heritability (h2) of variables was estimated using SOLAR software.
Results: In this study, 2460 individuals (493 fathers, 573 mothers, 720 sans, 674 daughters) participated, and the mean age of parents and offspring were 45.7±10.2 and 18.4±9.7 years respectively. In Tehran families, the sex and age adjusted heritability for anthropometric variables varied from 0.21(0.037) (hip) to 0.51(0.035) (BS) as expected, body size as a skeletal trait had the highest heritability. By considering the BS as a confounder, the REE heritability increased from 0.26 to 0.47. Therefore body size may have important role in determining the heritability of this variable.
Conclusion: genetic factors have decisive role in obesity phenotype of Tehran families.
Reza Ghadimi, Sadat Hoseini Seiyedi, Hasan Ashrafian Amiri, Seiyed Davoud Nasrollahpour Shirvani,
Volume 15, Issue 5 (7-2016)
Abstract
Background: In recent years, waist and hip circumference measurements simultaneously used as anthropometric factors to determine the prevalence of overweight and obesity in adults, in addition to Body Mass Index. Some studies have confirmed the relationship between the above mentioned factors and the hematological parameters of cardiometabolic disorders. This study aimed to determine the association between anthropometric factors and hematological factors in 25-60 years old couples of Babol, Mazandaran.
Methods: This cross-sectional descriptive study was conducted in spring 2014, on research population of 25-60 year old couples who were selected by random cluster. Data collected through a researcher-made questionnaire containing about demographic variables, underlying factors, dependent variables; its validity and reliability were confirmed. The collected data were analyzed by SPSS18 software.
Results: Men’s BMI had significant direct relationship with systolic and diastolic blood pressure, fasting blood sugar, cholesterol and triglycerides (p<0.05). Women’s BMI had a significant direct relations with systole and diastole blood pressure, fasting blood sugar and triglycerides (p<0.05). There was a significant direct relationship between men’s and women’s Waist/Hip Ratio (WHR) with systole and diastole blood pressure, fasting blood sugar, cholesterol and triglycerides (p<0.05). There was a significant direct relationship between men’s and women’s anthropometric indices (apart from the BMI) associated with serum biomarkers of cardiometabolic disorders (p<0.05).
Conclusion: The results showed that increased BMI and WHR in couples, increases the amount of cardiometabolic serum biomarkers and may directly and indirectly cause the risk of chronic diseases.
